Rv3601c - aspartate 1-decarboxylase precursor panD

Expression: Most Significant Conditions for Rv3601c

Protein Domains

Gene Information
Locus	Rv3601c
Symbol	panD
Gene Name	aspartate 1-decarboxylase precursor panD
Location	4043862 - 4044281 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:420 bp Protein:140 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	19475
Related Genes	CE0135 cg0172 jk0292 MAP0457 MAV_0552 Mkms_4847 ML0231 Mmcs_4761 MSMEG_0021 MUL_4183 Mvan_5363 nfa4070
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3601c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3601c Transcript 1
MLRTMLKSKIHRATVTCADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAI
TGERGSGVIGINGAAAHLVHPGDLVILIAYATMDDARARTYQPRIVFVDAYNKPIDMGHD
PAFVPENAGELLDPRLGVG*

Genomic Sequence

>Rv3601c
ATGTTACGGACGATGCTGAAGTCGAAGATCCACCGCGCCACGGTGACCTGCGCCGACCTG
CACTACGTCGGCTCGGTGACCATCGATGCCGACTTGATGGACGCCGCCGACCTGCTGGAA
GGCGAACAGGTAACCATCGTCGATATCGACAACGGTGCTCGACTGGTCACCTACGCGATC
ACCGGCGAACGCGGCAGTGGTGTGATTGGCATCAACGGTGCCGCCGCGCACTTGGTGCAT
CCGGGGGATCTGGTGATTCTGATTGCGTACGCGACGATGGACGACGCCCGGGCCCGCACA
TACCAGCCGCGGATCGTGTTTGTCGACGCTTACAACAAACCGATCGACATGGGCCACGAT
CCGGCATTTGTGCCCGAAAACGCGGGCGAGCTGCTAGACCCCCGGCTCGGTGTGGGATAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv0981	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. H. He, R. Hovey et al. MprAB is a stress-responsive two-component system that directly regulates expression of sigma factors SigB and SigE in Mycobacterium tuberculosis. J. Bacteriol. 2006
Term	EC:4.1.1.11 Aspartate 1-decarboxylase. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay authors,VK. Sambandamurthy,X. Wang,B. Chen,RG. Russell,S. Derrick,FM. Collins,SL. Morris,WR. Jacobs A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis. Nat. Med. 2002