Rv3858c - NADH-dependent glutamate synthase small subunit gltD

Expression: Most Significant Conditions for Rv3858c

Protein Domains

Gene Information
Locus	Rv3858c
Symbol	gltD
Gene Name	NADH-dependent glutamate synthase small subunit gltD
Location	4330039 - 4331505 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1467 bp Protein:489 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	35127
Related Genes	MAP0173 MAV_0167 Mkms_5153 ML0062 Mmcs_5065 MSMEG_6458 MT3973 MUL_5036 Mvan_5697 nfa970
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3858c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3858c Transcript 1
MADPGGFLKYTHRKLPKRRPVPLRLRDWREVYEEFDNESLRQQATRCMDCGIPFCHNGCP
LGNLIPEWNDLVRRGRWRDAIERLHATNNFPDFTGRLCPAPCEPACVLGINQDPVTIKQI
ELEIIDKAFDEGWVQPRPPRKLTGQTVAVVGSGPAGLAAAQQLTRAGHTVTVFEREDRIG
GLLRYGIPEFKMEKRHLDRRLDQMRSEGTEFRPGVNVGVDISAEKLRADFDAVVLAGGAT
AWRELPIPGRELEGVHQAMEFLPWANRVQEGDDVLDEDGQPPITAKGKKVVIIGGGDTGA
DCLGTVHRQGAIAVHQFEIMPRPPDARAESTPWPTYPLMYRVSAAHEEGGERVFSVNTEA
FVGTDGRVSALRAHEVTMLDGKFVKVEGSDFELEADLVLLAMGFVGPERAGLLTDLGVKF
TERGNVARGDDFDTSVPGVFVAGDMGRGQSLIVWAIAEGRAAAAAVDRYLMGSSALPAPV
KPTAAPLQ*

Genomic Sequence

>Rv3858c
ATGGCTGATCCGGGCGGCTTCCTCAAATACACCCACCGGAAATTGCCGAAGCGACGGCCG
GTCCCGCTGCGGCTGCGAGACTGGCGGGAAGTCTACGAGGAATTCGACAACGAGAGCCTG
CGCCAACAGGCGACCCGCTGCATGGATTGCGGCATTCCGTTCTGTCACAACGGATGTCCG
CTGGGTAACTTGATCCCGGAATGGAACGATCTGGTCCGCCGGGGCCGCTGGCGCGACGCA
ATCGAACGGCTGCACGCCACCAACAACTTCCCCGACTTCACCGGCCGGTTGTGCCCGGCT
CCGTGCGAGCCGGCGTGTGTGCTGGGCATCAACCAGGATCCGGTGACGATCAAGCAGATC
GAGCTGGAGATCATCGACAAGGCCTTCGACGAAGGATGGGTGCAACCACGTCCGCCGCGG
AAGCTGACCGGGCAAACGGTTGCTGTGGTGGGTTCGGGGCCGGCGGGTTTGGCCGCCGCC
CAGCAACTCACCCGGGCGGGTCACACCGTCACCGTTTTCGAGCGCGAAGACCGCATCGGC
GGGCTGCTGCGTTACGGCATCCCGGAATTCAAGATGGAAAAGCGGCATCTTGATCGGCGT
TTGGACCAAATGCGCTCCGAAGGAACCGAATTCCGGCCGGGCGTCAACGTCGGGGTCGAC
ATTAGCGCCGAAAAGCTGCGCGCTGATTTCGATGCGGTCGTATTGGCCGGTGGCGCAACC
GCTTGGCGCGAGCTGCCGATTCCCGGCCGCGAGCTGGAGGGCGTCCATCAGGCGATGGAG
TTTCTGCCGTGGGCCAACCGGGTGCAAGAAGGAGATGACGTCCTCGATGAGGACGGGCAG
CCGCCGATCACCGCAAAGGGCAAGAAGGTCGTCATCATCGGTGGCGGCGACACCGGGGCG
GACTGCCTGGGTACCGTGCACCGCCAGGGCGCGATCGCCGTGCACCAGTTCGAGATCATG
CCGCGTCCACCGGACGCCCGCGCCGAATCCACCCCATGGCCGACTTACCCGCTGATGTAT
CGGGTATCGGCCGCGCATGAGGAGGGTGGCGAGCGGGTGTTCTCGGTCAACACCGAGGCG
TTCGTCGGCACGGACGGGCGCGTGAGCGCGCTGCGGGCACACGAAGTGACCATGCTGGAT
GGCAAGTTCGTCAAGGTTGAGGGCTCCGACTTCGAGCTCGAAGCCGACCTGGTGTTGCTG
GCGATGGGTTTCGTCGGCCCGGAACGGGCGGGCCTGTTGACCGACCTCGGAGTGAAGTTC
ACCGAGCGTGGGAACGTGGCCCGTGGCGACGACTTCGACACCTCGGTTCCTGGTGTGTTC
GTAGCCGGTGACATGGGCCGGGGCCAGTCATTGATCGTCTGGGCGATTGCCGAGGGCCGG
GCCGCTGCCGCGGCCGTAGACCGGTACTTGATGGGTTCCAGTGCCCTGCCGGCGCCTGTT
AAGCCGACCGCTGCACCGCTTCAATAA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv3291c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv3291c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006
Term	EC:1.4.1.13 Glutamate synthase (NADPH). - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay authors,SH. Fisher Glutamate synthesis in Streptomyces coelicolor. J. Bacteriol. 1989