Rv2770c - PPE family protein

Expression: Most Significant Conditions for Rv2770c

Protein Domains

Gene Information
Locus	Rv2770c
Symbol	PPE44
Gene Name	PPE family protein
Location	3079309 - 3080457 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1149 bp Protein:383 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	11805
Related Genes	MT2840 MUL_2167
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2770c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2770c Transcript 1
MDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGP
ASLSMAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAEL
TATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLA
HQAAAVGQAGASAFARQVGLSHLISDVADAVLSFASPVMSAADTGLEAVRQFLNLDVPLF
VESAFHGLGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGVGGTALT
ADLGNASVVGRLSVPASWSTAAPATAAGAALDGTGWAVPEEDGPIAVMPPAPGMVVAANS
VGADSGPRYGVKPIVMPKHGLF*

Genomic Sequence

>Rv2770c
GTGGATTTTGGAGCTCTACCTCCGGAGGTCAATTCTGCGCGCATGTATGGCGGCGCGGGC
GCGGCAGACCTGCTGGCGGCTGCGGCTGCGTGGAACGGCATAGCTGTCGAGGTGAGCACA
GCTGCGTCCTCCGTCGGGTCGGTCATCACGCGGCTGAGCACCGAGCACTGGATGGGTCCC
GCATCGTTGTCGATGGCCGCCGCGGTGCAGCCCTATTTGGTCTGGTTGACCTGCACCGCT
GAATCCTCGGCGCTCGCGGCGGCACAGGCCATGGCGTCTGCGGCCGCCTTTGAAACGGCG
TTTGCGCTGACAGTGCCCCCGGCCGAGGTGGTTGCCAACAGAGCCCTGTTGGCTGAACTG
ACAGCGACCAACATCCTTGGGCAAAACGTGTCGGCCATCGCGGCTACCGAGGCACGCTAT
GGCGAAATGTGGGCCCAAGACGCTTCGGCCATGTACGGCTATGCGGCCGCATCCGCGGTC
GCCGCAAGACTGAACCCGCTGACCAGGCCGTCGCACATCACCAATCCGGCCGGGCTCGCA
CACCAAGCCGCCGCTGTTGGCCAAGCCGGCGCATCCGCTTTCGCGCGCCAGGTGGGTCTG
AGCCACCTGATCAGCGACGTCGCCGACGCTGTCCTGAGCTTCGCCTCCCCGGTGATGTCC
GCGGCCGATACCGGGTTGGAGGCGGTCAGGCAGTTCCTCAATCTCGATGTTCCGCTGTTC
GTAGAATCCGCGTTTCACGGCCTGGGTGGCGTGGCAGACTTTGCCACGGCCGCCATTGGC
AATATGACGCTTCTTGCCGATGCTATGGGAACCGTTGGCGGAGCCGCTCCAGGTGGCGGC
GCGGCAGCCGCGGTGGCACACGCGGTTGCCCCAGCGGGCGTCGGCGGAACAGCGCTGACC
GCCGATTTGGGCAATGCGTCCGTGGTTGGTCGCCTGTCGGTGCCGGCAAGCTGGTCTACT
GCAGCGCCGGCGACGGCAGCCGGCGCGGCCTTGGATGGCACAGGCTGGGCAGTTCCCGAG
GAGGACGGCCCGATCGCAGTGATGCCGCCTGCCCCTGGAATGGTCGTAGCCGCCAACAGT
GTTGGTGCCGACTCCGGACCACGGTACGGAGTCAAGCCGATTGTTATGCCCAAGCACGGC
CTCTTCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	PhysicalInteraction Rv2769c	active	gaat3s	2012-10-05
	Operon (Functional linkage) authors,NC. Gey van Pittius,SL. Sampson,H. Lee,Y. Kim,PD. van Helden,RM. Warren Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions. BMC Evol. Biol. 2006
Interaction	PhysicalInteraction Rv2769c	active	gaat3s	2012-10-05
	Operon (Functional linkage) authors,M. Strong,MR. Sawaya,S. Wang,M. Phillips,D. Cascio,D. Eisenberg Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A. 2006
Interaction	PhysicalInteraction Rv2769c	active	gaat3s	2012-10-05
	Operon (Functional linkage) authors,NC. Gey van Pittius,SL. Sampson,H. Lee,Y. Kim,PD. van Helden,RM. Warren Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions. BMC Evol. Biol. 2006
Interaction	PhysicalInteraction Rv2769c	active	gaat3s	2012-10-05
	Operon (Functional linkage) authors,M. Strong,MR. Sawaya,S. Wang,M. Phillips,D. Cascio,D. Eisenberg Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A. 2006