Rv1977 - conserved hypothetical protein

Expression: Most Significant Conditions for Rv1977

Protein Domains

Gene Information
Locus	Rv1977
Symbol
Gene Name	conserved hypothetical protein
Location	2219754 - 2220800 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1047 bp Protein:349 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	12246
Related Genes	Acel_1421 MSMEG_3476 MT2029 SAV5476
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1977
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1977 Transcript 1
MSQTPATTRKTFPEISSRAWEHPADRTALSALRRLKGFDQILKLMSGMLRERQHRLLYLA
SAARVGPRQFADLDALLDECVDVLDASAKPELYVMQSPIADAFTIGMGKPFTVITSGLYD
LVTHDEMRFVMGHELGHALSGHAVYRTMMMHLLRLARSFGVLPVGGWALRAIVAALLEWQ
RKSELSGDRAGLLCAQDLDTALRVEMKLAGGCRLDKLDSEAFLAQAREYETSGDMRDGVL
KLLNLELQTHPFSVLRAAALTHWVDTGGYAKVIAGEYPRRADDGNAKFADDLGAAARYYR
DGFDQSNDPLIKGIRDGFGGIVEGVGRAASNAADSLGRKITEWRQPSK*

Genomic Sequence

>Rv1977
ATGTCTCAGACACCCGCTACAACCCGCAAAACGTTTCCCGAGATCAGCTCAAGAGCGTGG
GAGCACCCCGCCGACCGGACCGCCCTTTCCGCGCTGCGCCGGCTCAAAGGCTTCGACCAG
ATCTTGAAGCTGATGTCGGGGATGTTGCGGGAACGGCAGCACCGGCTGCTGTACCTGGCC
AGCGCGGCACGGGTCGGGCCGCGGCAGTTCGCCGACCTCGACGCGCTGCTGGACGAATGC
GTGGATGTGCTGGACGCGTCGGCGAAACCCGAACTCTACGTGATGCAGTCACCAATCGCG
GATGCCTTCACCATCGGCATGGGCAAGCCATTCACCGTGATCACCTCGGGGCTGTACGAC
CTGGTGACACACGACGAGATGCGGTTCGTGATGGGCCACGAGCTCGGCCACGCACTGTCC
GGCCACGCGGTGTACCGCACGATGATGATGCATCTGCTGCGGTTGGCCCGGTCATTCGGC
GTCTTGCCGGTTGGCGGCTGGGCGCTGCGCGCAATCGTGGCTGCGCTGCTGGAATGGCAG
CGCAAATCGGAGCTGTCCGGCGATCGCGCTGGGTTGCTGTGCGCGCAGGATTTGGACACC
GCGCTCAGGGTGGAGATGAAGCTCGCTGGCGGCTGCCGGCTGGACAAGCTGGACTCGGAG
GCCTTCTTGGCTCAGGCCCGGGAATACGAGACATCCGGCGATATGCGCGACGGGGTGCTC
AAGCTGCTCAACCTGGAGCTGCAGACCCATCCGTTCTCTGTGCTGCGGGCTGCCGCCTTG
ACTCACTGGGTGGACACCGGCGGCTATGCCAAGGTGATAGCCGGCGAGTACCCGCGTCGG
GCCGACGACGGCAACGCCAAATTTGCAGACGACCTTGGCGCGGCCGCCCGGTACTACCGG
GACGGCTTCGACCAGTCCAACGACCCGCTGATCAAAGGTATCCGCGACGGATTCGGTGGC
ATCGTCGAGGGCGTGGGACGGGCAGCCTCGAACGCGGCCGATTCATTGGGCCGCAAGATC
ACCGAGTGGCGGCAGCCCTCGAAGTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Transcription Rv3676	active	jgalag	2012-10-05
	Band shift M. Stapleton, I. Haq et al. Mycobacterium tuberculosis cAMP receptor protein (Rv3676) differs from the Escherichia coli paradigm in its cAMP binding and DNA binding properties and transcription activation properties. J. Biol. Chem. 2010
Interaction	Transcription Rv3676	active	jgalag	2012-10-05
	Band shift G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	ActivatedBy Rv1975	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression authors,MC. Garcia-Pelayo,KC. Caimi,JK. Inwald,J. Hinds,F. Bigi,MI. Romano,D. van Soolingen,RG. Hewinson,A. Cataldi,SV. Gordon Microarray analysis of Mycobacterium microti reveals deletion of genes encoding PE-PPE proteins and ESAT-6 family antigens. Tuberculosis (Edinb) 2004
Interaction	RegulatedBy Rv3676	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008