Rv0081 - transcriptional regulator

Expression: Most Significant Conditions for Rv0081

Protein Domains

Gene Information
Locus	Rv0081
Symbol
Gene Name	transcriptional regulator
Location	89575 - 89919 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:345 bp Protein:115 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	31948
Related Genes	MAP0250 MAV_0248 MAV_5108 Mkms_4402 Mkms_5072 Mkms_5150 Mmcs_4316 Mmcs_4984 Mmcs_5062 MSMEG_6451 MSMEG_6832 MT0088 MT3882 MUL_4409 Mvan_5692 Mvan_5694 nfa31100 nfa4690 Rv3773c
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0081
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0081 Transcript 1
MESEPLYKLKAEFFKTLAHPARIRILELLVERDRSVGELLSSDVGLESSNLSQQLGVLRR
AGVVAARRDGNAMIYSIAAPDIAELLAVARKVLARVLSDRVAVLEDLRAGGSAT*

Genomic Sequence

>Rv0081
GTGGAGTCCGAACCGCTGTACAAGCTCAAGGCGGAGTTCTTCAAAACCCTTGCGCATCCG
GCGCGGATCAGGATTTTGGAGCTGCTGGTCGAGCGGGACCGTTCGGTCGGTGAGTTGCTG
TCCTCGGACGTCGGCCTGGAGTCGTCGAACCTGTCCCAGCAGCTGGGTGTGCTACGCCGG
GCGGGTGTTGTCGCGGCACGTCGTGACGGCAACGCGATGATCTATTCGATTGCCGCACCC
GATATCGCCGAGCTGCTGGCGGTGGCACGCAAGGTGCTGGCCAGGGTGCTCAGCGACCGG
GTGGCGGTGCTAGAGGACCTCCGCGCCGGCGGCTCGGCCACGTAA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv3133c	active	harsharohiratruefriend	2012-10-05
	GF. Black,BA. Thiel,MO. Ota,SK. Parida,R. Adegbola,WH. Boom,HM. Dockrell,KL. Franken,AH. Friggen,PC. Hill,MR. Klein,MK. Lalor,H. Mayanja,G. Schoolnik,K. Stanley,K. Weldingh,SH. Kaufmann,G. Walzl,TH. Ottenhoff,null. null Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa. Clin. Vaccine Immunol. 2009
Interaction	RegulatedBy Rv0182c	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. JH. Lee, DE. Geiman et al. Role of stress response sigma factor SigG in Mycobacterium tuberculosis. J. Bacteriol. 2008
Interaction	RegulatedBy Rv3133c	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. HD. Park, KM. Guinn et al. Rv3133c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis. Mol. Microbiol. 2003