Rv0449c - conserved hypothetical protein

Expression: Most Significant Conditions for Rv0449c

Protein Domains

Gene Information
Locus	Rv0449c
Symbol
Gene Name	conserved hypothetical protein
Location	537229 - 538548 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1320 bp Protein:440 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	24937
Related Genes	Mkms_4457 Mmcs_4370 MT0464 MT0465 MUL_1403 MUL_1404 Mvan_4926 Rv0448c
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0449c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0449c Transcript 1
MQQSLRRSVAVVGSGVAGLTAAYILSGRDRVTLYEADGRLGGHAHTHYLDNGGGPRGTDV
VGVDSAFLVHNDRTYPTLCRLFAELGVATQESEMSMSVRADDIGLEYAGALGARGLFACR
QSLRPRYLCMLAEILRFHRAAARLLREETDNAEDKPETLEAFLSRHHFSQYFVDYFITPL
VAAVWSCGGADALRYPARYLFVFLDHHGMLSVFGSPTWRTVTGGSANYVQAIAAQLDEVS
TRTPVHSLRRLPDGVLVGAGDGPSRRFDAAVVAVHPDQALLLLDEPTPAERAVLGAIAYS
TNSAQLHTDESVLPRHHRARASWNYLVTPGQHQVVVSYDISRLMRLDGGRRYLVTLGGHD
RVDPSSVIAEMTYSHPLYTPESVAAQRLLPTLGDNRVVFAGAYHGWGFHEDGAASGLRAA
RRLGADWPAAIPQEAMVAC*

Genomic Sequence

>Rv0449c
GTGCAGCAATCACTCCGACGATCGGTGGCTGTTGTCGGAAGTGGGGTCGCCGGCCTCACC
GCCGCCTACATCCTGTCTGGACGGGACCGAGTCACCCTGTACGAGGCGGACGGCCGGCTG
GGCGGTCATGCCCACACCCACTATCTGGACAACGGTGGCGGCCCCCGGGGCACCGACGTC
GTCGGCGTCGACTCGGCGTTCCTGGTGCACAACGACCGAACCTATCCAACGTTGTGCCGA
TTGTTCGCCGAACTGGGTGTGGCCACCCAGGAGTCGGAAATGTCGATGTCGGTGCGCGCC
GACGACATCGGACTCGAATATGCCGGCGCACTGGGAGCGCGCGGGCTGTTCGCTTGCCGG
CAATCGCTGCGGCCACGGTATCTGTGCATGCTTGCCGAGATTCTCCGCTTCCACCGCGCC
GCGGCTCGCCTGCTGCGTGAGGAGACCGACAACGCGGAAGACAAACCGGAGACGCTGGAA
GCCTTCCTGAGCCGGCACCACTTCTCGCAGTATTTCGTCGATTACTTCATCACACCCTTG
GTCGCCGCCGTGTGGTCCTGCGGCGGGGCCGACGCCTTGCGCTATCCGGCCCGGTATCTG
TTCGTCTTCCTCGACCATCACGGCATGCTGTCGGTGTTCGGGTCGCCAACCTGGCGTACC
GTCACCGGAGGTTCCGCCAACTACGTGCAGGCGATCGCAGCTCAGCTGGACGAGGTGTCG
ACCCGCACGCCAGTGCACTCGCTGCGCCGGCTGCCGGACGGGGTATTGGTGGGCGCGGGT
GATGGGCCGTCGCGGCGTTTCGATGCGGCCGTCGTCGCGGTCCATCCCGACCAGGCGCTG
CTGTTGCTCGACGAGCCGACACCGGCCGAGCGCGCGGTCCTGGGCGCGATCGCATACTCC
ACCAACAGCGCCCAGCTGCACACCGACGAGTCGGTCCTGCCCCGCCACCATCGCGCCCGC
GCATCCTGGAACTACCTGGTGACACCCGGGCAGCACCAGGTCGTGGTCAGCTACGACATC
AGCAGGCTAATGCGCCTCGACGGTGGCCGCCGGTATCTGGTCACCCTCGGCGGCCACGAC
CGGGTTGATCCCAGCTCGGTGATCGCCGAGATGACCTACAGCCATCCGCTGTACACACCG
GAATCGGTTGCAGCCCAACGCTTATTGCCGACGCTGGGTGACAATCGGGTGGTATTCGCC
GGCGCCTACCACGGCTGGGGATTCCACGAGGACGGCGCCGCCTCGGGTCTGCGGGCGGCC
CGGCGCCTTGGCGCCGACTGGCCGGCAGCGATCCCACAGGAGGCGATGGTCGCGTGCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Transcription Rv0445c	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) F. Veyrier, B. Saïd-Salim et al. Evolution of the mycobacterial SigK regulon. J. Bacteriol. 2008
Interaction	Transcription Rv0445c	active	sourish10	2012-10-05
	Co-expression (Functional linkage) D. Charlet, S. Mostowy et al. Reduced expression of antigenic proteins MPB70 and MPB83 in Mycobacterium bovis BCG strains due to a start codon mutation in sigK. Mol. Microbiol. 2005
Interaction	Transcription Rv0445c	active	sourish10	2012-10-05
	Co-expression (Functional linkage) F. Veyrier, B. Saïd-Salim et al. Evolution of the mycobacterial SigK regulon. J. Bacteriol. 2008