Rv0450c - transmembrane transport protein mmpL4

Expression: Most Significant Conditions for Rv0450c

Protein Domains

Gene Information
Locus	Rv0450c
Symbol	mmpL4
Gene Name	transmembrane transport protein mmpL4
Location	538588 - 541491 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:2904 bp Protein:968 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	22742
Related Genes	MAP3947 MAV_4696 ML2378 MT0466
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0450c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0450c Transcript 1
MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFVPSLEAVGQERSVSL
SPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQ
SVQDLWGDPLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTPAPPGIKA
YVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAAR
GVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEAAYYTMYR
GTAHVILGSGLTIAGATFCLSFARMPYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRF
GLFDPKRLLKVRGWRRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFI
PANQGYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAIT
RPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAE
MASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPICWSFRSIFD
ALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQ
MLEMSDNATAMGKAFDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGD
PQSPEGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLC
LIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLA
VGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASMAVSDLRVIGQ
VGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLA
MSSDRLG*

Genomic Sequence

>Rv0450c
GTGAGTACTAAATTCGCGAACGACTCCAATACCAACGCTCGCCCCGAAAAGCCATTCATC
GCCAGGATGATCCACGCCTTTGCGGTACCGATCATCCTTGGCTGGCTGGCAGTTTGCGTC
GTTGTCACCGTATTTGTCCCGTCACTGGAAGCTGTCGGCCAAGAGCGATCGGTGTCGCTG
AGTCCCAAGGATGCACCGTCGTTTGAGGCGATGGGACGTATCGGCATGGTGTTCAAGGAA
GGCGATTCCGACAGTTTCGCGATGGTCATAATAGAGGGTAACCAACCCCTTGGCGACGCT
GCCCATAAGTATTACGACGGCCTGGTTGCTCAATTGAGGGCCGATAAGAAGCACGTGCAA
AGTGTCCAAGATTTATGGGGGGACCCACTCACCGCCGCGGGCGTGCAAAGTAACGACGGC
AAGGCCGCCTATGTTCAACTGTCACTTGCCGGCAACCAAGGCACGCCGCTGGCCAACGAA
TCCGTCGAGGCAGTACGCAGCATCGTCGAAAGCACGCCCGCGCCGCCGGGCATAAAGGCC
TATGTGACCGGACCATCCGCACTCGCCGCGGATATGCACCACAGTGGCGATAGATCCATG
GCCAGGATCACCATGGTTACGGTCGCCGTGATCTTTATTATGTTGTTGCTCGTCTACCGG
TCGATAATCACCGTGGTTCTCCTGCTGATCACGGTGGGGGTCGAATTGACGGCTGCGCGC
GGAGTCGTAGCGGTTCTGGGGCATAGCGGGGCTATCGGACTTACCACCTTTGCGGTGAGC
TTGCTGACTTCGCTGGCAATCGCGGCCGGTACGGACTACGGGATATTCATCATCGGGCGC
TACCAGGAAGCCCGCCAAGCCGGCGAGGACAAAGAGGCCGCCTACTACACCATGTACCGC
GGGACCGCCCACGTGATTCTGGGCTCTGGATTGACCATCGCCGGAGCTACCTTTTGCCTG
AGCTTTGCCCGCATGCCCTACTTTCAAACCCTGGGCATCCCCTGCGCGGTGGGGATGCTA
GTCGCAGTGGCGGTCGCGTTGACGCTGGGTCCGGCCGTCCTACACGTCGGCAGCCGGTTC
GGCCTGTTCGACCCTAAGCGGCTCCTCAAAGTCCGTGGCTGGCGGCGGGTGGGTACCGTG
GTGGTTCGCTGGCCGCTGCCCGTTCTCGTCGCCACCTGCGCGATCGCCCTAGTCGGTCTG
CTCGCCCTGCCTGGATACAAAACCAGCTACAACGACCGTGACTACCTACCGGACTTCATA
CCCGCCAACCAAGGATATGCGGCCGCGGATCGTCATTTCTCTCAGGCCAGGATGAAGCCC
GAGATCCTAATGATTGAATCCGATCACGATATGCGGAATCCGGCAGATTTTCTGGTCCTG
GACAAGCTGGCTAAAGGCATCTTCCGGGTCCCGGGCATTTCCCGTGTGCAAGCAATTACC
CGGCCCGAAGGAACGACGATGGACCACACGTCGATCCCGTTCCAGATCAGCATGCAAAAT
GCCGGTCAGCTGCAGACCATAAAGTACCAGCGCGACCGGGCGAACGACATGCTGAAGCAG
GCCGACGAGATGGCCACGACGATTGCGGTGTTGACGCGGATGCATAGCTTGATGGCGGAG
ATGGCCAGTACTACCCACCGCATGGTCGGCGACACCGAAGAGATGAAGGAGATCACCGAA
GAATTACGCGACCACGTCGCGGATTTTGATGATTTCTGGAGACCAATTCGAAGCTATTTC
TACTGGGAAAAGCACTGCTACGGAATTCCGATCTGTTGGTCGTTCAGATCGATATTCGAT
GCACTGGACGGAATCGACAAGCTCAGCGAGCAAATAGGCGTCCTCTTGGGCGACTTGCGC
GAGATGGATCGCCTCATGCCACAAATGGTCGCGCAGATCCCGCCGCAGATTGAGGCCATG
GAAAACATGCGGACCATGATTCTTACCATGCACAGCACCATGACCGGAATCTTCGACCAG
ATGCTCGAAATGAGCGACAATGCCACAGCCATGGGTAAGGCTTTTGACGCCGCCAAGAAC
GACGACTCGTTCTACCTTCCACCCGAGGTTTTCAAGAACAAAGACTTCCAGCGCGCCATG
AAGTCGTTCCTGTCTTCGGACGGACACGCGGCCCGGTTTATCATCCTGCACAGGGGGGAT
CCGCAATCACCCGAGGGCATCAAAAGTATCGACGCGATTCGTACCGCGGCCGAGGAATCG
CTCAAGGGAACTCCACTAGAAGACGCCAAGATCTACCTGGCCGGCACGGCGGCCGTCTTC
CACGACATCTCCGAGGGCGCCCAATGGGACCTTCTTATCGCGGCAATTTCGTCCCTCTGT
CTCATTTTTATCATCATGCTGATCATCACACGGGCCTTTATTGCCGCCGCCGTCATTGTG
GGCACAGTCGCACTTTCACTGGGTGCCTCTTTCGGACTATCGGTGCTGCTCTGGCAGCAT
ATTCTCGCAATCCATCTGCATTGGCTCGTGCTTGCGATGTCGGTCATCGTTCTGTTGGCG
GTGGGATCTGACTACAATCTGCTCTTGGTCTCCCGGTTCAAACAGGAAATAGGAGCGGGG
CTGAAGACCGGCATCATCCGGTCGATGGGCGGCACCGGCAAGGTCGTGACCAACGCAGGG
CTGGTATTCGCCGTCACCATGGCGTCCATGGCCGTCAGCGATCTGCGGGTTATCGGACAG
GTGGGCACCACCATCGGTCTGGGTTTGCTGTTCGACACGTTGATCGTGCGATCGTTCATG
ACGCCATCCATCGCCGCACTACTGGGCCGCTGGTTCTGGTGGCCGCTGCGGGTGCGTTCC
CGGCCCGCCCGGACCCCGACCGTACCCAGCGAAACCCAGCCCGCGGGCCGGCCCTTGGCG
ATGAGCAGCGACCGCCTCGGCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv2711	active	priyadarshinipriyanka2001	2012-10-05
	G. Lamichhane, S. Tyagi et al. Designer arrays for defined mutant analysis to detect genes essential for survival of Mycobacterium tuberculosis in mouse lungs. Infect. Immun. 2005
Interaction	Regulatory Rv2711	active	priyadarshinipriyanka2001	2012-10-05
	P. Domenech, MB. Reed et al. Contribution of the Mycobacterium tuberculosis MmpL protein family to virulence and drug resistance. Infect. Immun. 2005
Interaction	Regulatory Rv2711	active	priyadarshinipriyanka2001	2012-10-05
	GM. Rodriguez, MI. Voskuil et al. ideR, An essential gene in mycobacterium tuberculosis: role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress response. Infect. Immun. 2002
Interaction	Regulatory Rv2711	active	priyadarshinipriyanka2001	2012-10-05
	authors,LR. Camacho,D. Ensergueix,E. Perez,B. Gicquel,C. Guilhot Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature-tagged transposon mutagenesis. Mol. Microbiol. 1999
Interaction	RegulatedBy Rv2711	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. GM. Rodriguez, MI. Voskuil et al. ideR, An essential gene in mycobacterium tuberculosis: role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress response. Infect. Immun. 2002