Rv0662c - conserved hypothetical protein

Expression: Most Significant Conditions for Rv0662c

Protein Domains

Gene Information
Locus	Rv0662c
Symbol
Gene Name	conserved hypothetical protein
Location	755769 - 756137 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:369 bp Protein:123 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	8898
Related Genes	MT0691
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0662c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0662c Transcript 1
MFLPNTRAYRRYNRSVWAVRGSTRPQWQPPPKFQHAKCMSMRLAHRLQILLDDECHRRIT
AVARERGVPVATVVREAIDRGLVSPAGRRKSAGRRLLDAADMSVPEPRELKQELEALRAR
RG*

Genomic Sequence

>Rv0662c
TTGTTCCTCCCTAATACGCGTGCCTATCGACGCTACAACCGCAGCGTCTGGGCCGTCCGC
GGGTCAACGCGACCGCAATGGCAGCCGCCGCCCAAATTTCAGCATGCTAAATGTATGAGC
ATGCGTCTGGCGCATCGGCTCCAGATCCTGCTCGACGACGAGTGCCACCGCCGCATCACC
GCGGTGGCGCGCGAGCGAGGCGTCCCGGTCGCAACCGTCGTGCGTGAGGCCATTGATCGA
GGCCTCGTCAGCCCCGCCGGTCGCCGCAAGTCCGCGGGCAGGCGCCTGCTCGACGCCGCC
GACATGTCCGTTCCCGAGCCGCGGGAGCTGAAGCAGGAACTCGAGGCCCTCCGGGCGCGC
CGCGGATGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Inhibits Rv0661c	active	ashwinigbhat	2012-10-05
	Gene Neighborhood (Functional linkage) authors,HR. Ramage,LE. Connolly,JS. Cox Comprehensive functional analysis of Mycobacterium tuberculosis toxin-antitoxin systems: implications for pathogenesis, stress responses, and evolution. PLoS Genet. 2009
Interaction	Inhibits Rv0661c	active	priti.priety	2012-10-05
	Gene Neighborhood (Functional linkage) authors,HR. Ramage,LE. Connolly,JS. Cox Comprehensive functional analysis of Mycobacterium tuberculosis toxin-antitoxin systems: implications for pathogenesis, stress responses, and evolution. PLoS Genet. 2009
Interaction	Inhibits Rv0661c	active	ashwinigbhat	2012-10-05
	Gene Neighborhood (Functional linkage) authors,HR. Ramage,LE. Connolly,JS. Cox Comprehensive functional analysis of Mycobacterium tuberculosis toxin-antitoxin systems: implications for pathogenesis, stress responses, and evolution. PLoS Genet. 2009
Interaction	Inhibits Rv0661c	active	priti.priety	2012-10-05
	Gene Neighborhood (Functional linkage) authors,HR. Ramage,LE. Connolly,JS. Cox Comprehensive functional analysis of Mycobacterium tuberculosis toxin-antitoxin systems: implications for pathogenesis, stress responses, and evolution. PLoS Genet. 2009
Symbol	VapB7	active	jlew	2012-03-07
	We report the heterologous toxicity of these TA loci in Escherichia coli and show that only a few of the M. tuberculosis-encoded toxins can inhibit E. coli growth and have a killing effect. This killing effect can be suppressed by coexpression of the cognate antitoxin. authors,A. Gupta Killing activity and rescue function of genome-wide toxin-antitoxin loci of Mycobacterium tuberculosis. FEMS Microbiol. Lett. 2009
Other	strand:+	active	rslayden	2012-03-05
	Conserved hypothetical protein, showing weak similarity with other hypothetical proteins from Mycobacterium tuberculosis e.g. Rv2871, Rv1241, Rv2550c, etc.
Other	stop:756137	active	rslayden	2012-03-05
	Conserved hypothetical protein, showing weak similarity with other hypothetical proteins from Mycobacterium tuberculosis e.g. Rv2871, Rv1241, Rv2550c, etc.
Other	start:755769	active	rslayden	2012-03-05
	Conserved hypothetical protein, showing weak similarity with other hypothetical proteins from Mycobacterium tuberculosis e.g. Rv2871, Rv1241, Rv2550c, etc.
Symbol	Vap BC-7	active	rslayden	2012-03-05
	Conserved hypothetical protein, showing weak similarity with other hypothetical proteins from Mycobacterium tuberculosis e.g. Rv2871, Rv1241, Rv2550c, etc.