Rv0681 - transcriptional regulator, tetR-family

Expression: Most Significant Conditions for Rv0681

Protein Domains

Gene Information
Locus	Rv0681
Symbol
Gene Name	transcriptional regulator, tetR-family
Location	780721 - 781311 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:591 bp Protein:197 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	21470
Related Genes	MAP4139 MAV_4494 Mkms_1001 Mmcs_0983 MSMEG_1397 MT0709 MUL_0762 Mvan_1278
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0681
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0681 Transcript 1
MARPAKLSRESIVEGALTFLDREGWDSLTINALATQLGTKGPSLYNHVDSLEDLRRAVRI
RVIDDIITMLNRVGAGRARDDAVLVMAGAYRSYAHHHPGRYSAFTRMPLGGDDPEYTAAT
RGAAAPVIAVLSSYGLDGEQAFYAALEFWSALHGFVLLEMTGVMDDIDTDAVFTDMVLRL
AAGMERRTTHGGTAST*

Genomic Sequence

>Rv0681
GTGGCTCGCCCGGCCAAACTGAGCCGTGAGAGCATCGTCGAGGGCGCCCTGACCTTTTTG
GATCGGGAGGGGTGGGACTCGCTGACCATCAATGCGCTGGCGACCCAGCTCGGGACCAAG
GGGCCGTCGCTGTACAACCACGTGGACAGCCTCGAGGATCTACGCCGGGCGGTGCGGATT
CGGGTGATCGACGACATCATCACGATGCTGAATAGGGTCGGTGCGGGTCGCGCACGCGAT
GACGCGGTGTTGGTCATGGCCGGTGCCTACCGCAGCTACGCCCACCACCACCCGGGTCGG
TACTCGGCGTTCACCCGGATGCCGCTGGGCGGTGACGATCCCGAATACACCGCTGCGACT
AGGGGCGCAGCCGCGCCCGTCATCGCCGTGCTGTCCTCGTACGGCCTCGACGGTGAGCAG
GCTTTCTACGCGGCGCTCGAGTTTTGGTCGGCACTGCATGGGTTTGTGTTGCTGGAAATG
ACCGGCGTCATGGACGACATCGATACCGATGCGGTGTTCACCGACATGGTGCTGCGGCTG
GCGGCGGGCATGGAAAGGCGCACCACACACGGTGGTACCGCGTCAACGTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Transcription Rv3676	active	jgalag	2012-10-05
	Band shift M. Stapleton, I. Haq et al. Mycobacterium tuberculosis cAMP receptor protein (Rv3676) differs from the Escherichia coli paradigm in its cAMP binding and DNA binding properties and transcription activation properties. J. Biol. Chem. 2010
Interaction	Transcription Rv3676	active	jgalag	2012-10-05
	Band shift G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	Transcription Rv3676	active	sudhakar_dipu	2012-10-05
	ChIP (Physical interaction) authors,S. Rodrigue,J. Brodeur,PE. Jacques,AL. Gervais,R. Brzezinski,L. Gaudreau Identification of mycobacterial sigma factor binding sites by chromatin immunoprecipitation assays. J. Bacteriol. 2007
Interaction	Transcription Rv2069	active	sudhakar_dipu	2012-10-05
	ChIP (Physical interaction) authors,S. Rodrigue,J. Brodeur,PE. Jacques,AL. Gervais,R. Brzezinski,L. Gaudreau Identification of mycobacterial sigma factor binding sites by chromatin immunoprecipitation assays. J. Bacteriol. 2007
Interaction	Signaling Rv1266c	active	sudhakar_dipu	2012-10-05
	Structural Analysis X. Zheng, KG. Papavinasasundaram et al. Novel substrates of Mycobacterium tuberculosis PknH Ser/Thr kinase. Biochem. Biophys. Res. Commun. 2007
Interaction	Signaling Rv1266c	active	sudhakar_dipu	2012-10-05
	Spectrophotometric X. Zheng, KG. Papavinasasundaram et al. Novel substrates of Mycobacterium tuberculosis PknH Ser/Thr kinase. Biochem. Biophys. Res. Commun. 2007
Interaction	RegulatedBy Rv3676	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008