Rv0754 - PE-PGRS family protein

Expression: Most Significant Conditions for Rv0754

Protein Domains

Gene Information
Locus	Rv0754
Symbol	PE_PGRS11
Gene Name	PE-PGRS family protein
Location	846159 - 847913 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1755 bp Protein:585 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	22302
Related Genes	MAP3481 MAP3868 MAV_4339 MAV_4778 Mkms_5230 Mmcs_5141 MSMEG_6545 MT0778 MT3497 MUL_0919 Mvan_5262 Rv3390
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0754
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0754 Transcript 1
MSFVIVARDALAAAAADLAQIGSAVNAGNLAAANPTTAVAAAAADEVSAALAALFGAHAR
EYQAAAAQAAAYHEQFVHRLSAAATSYAVTEVTIATSLRGALGSAPASVSDGFQAFVYGP
IHATGQQWINSPVGEALAPIVNAPTNVLLGRDLIGNGVTGTAAAPNGGPGGLLFGDGGAG
YTGGNGGSAGLIGNGGTGGAGFAGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALL
FGNGGLGGAGGAGGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHGQTPGNAAML
IDTAVPGPGLTALGQQQAQAIANALAAKGPYAGIFDSQLIRTQQTAAPLANLLGMAPQVL
PGLNEIHAGIFEDLPQISPAGLLYLVGPIAWTLGFPIVPMLAPGSTDVNGIVFNRAFTGA
VQTIYDASLANPVVAADGNITSVAYSSAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAVVV
QGNPEGGWTLVSWDGIPVGPASLPTALFVDVRELITAPQYAAYDIWESLFTGDPAAVINA
VRDGADEVGAAVVQFPHAVADDVIDATGHPYLSGLPIGLPSLIP*

Genomic Sequence

>Rv0754
ATGTCATTTGTGATCGTGGCGCGGGACGCGTTGGCGGCGGCCGCGGCGGATCTAGCGCAG
ATCGGTTCGGCAGTGAATGCGGGCAATCTGGCCGCAGCCAATCCGACGACCGCTGTGGCG
GCGGCGGCCGCCGACGAGGTATCGGCGGCACTCGCGGCGCTGTTCGGCGCGCATGCCCGG
GAGTATCAGGCGGCGGCGGCGCAGGCAGCGGCGTATCACGAGCAGTTTGTGCACCGATTG
AGCGCGGCAGCGACATCGTATGCGGTTACCGAGGTGACCATCGCGACGTCGCTCCGGGGG
GCGCTGGGCTCGGCGCCCGCGTCCGTTTCCGACGGGTTCCAAGCGTTCGTCTATGGTCCG
ATTCACGCGACCGGCCAGCAATGGATCAACAGCCCGGTCGGCGAGGCGCTCGCCCCGATT
GTCAATGCGCCGACAAACGTGCTGCTCGGCCGCGATCTGATCGGCAACGGCGTCACCGGG
ACGGCGGCAGCTCCCAACGGTGGCCCCGGCGGTTTGCTATTCGGTGACGGTGGGGCCGGC
TATACCGGCGGTAACGGTGGGAGTGCCGGGTTAATCGGCAACGGGGGTACCGGTGGCGCC
GGCTTTGCCGGCGGAGTGGGCGGCATGGGCGGCACCGGCGGCTGGTTGATGGGCAACGGC
GGCATGGGTGGCGCGGGCGGTGTCGGCGGTAACGGCGGCGCCGGGGGCCAGGCGCTGTTG
TTCGGCAACGGCGGCCTGGGCGGAGCCGGCGGGGCTGGCGGGGTCGATGGGGCTATCGGT
CGTGGCGGGTGGTTCATCGGTACCGGCGGCATGGCCACGATCGGTGGTGGCGGCAACGGG
CAGTCGATCGTCATCGACTTCGTGCGGCACGGCCAGACGCCGGGCAACGCCGCAATGTTG
ATCGACACGGCGGTGCCCGGACCCGGACTCACCGCGCTGGGCCAGCAACAGGCGCAGGCC
ATCGCCAACGCGCTCGCGGCCAAGGGCCCCTATGCCGGGATCTTCGACTCGCAGTTGATC
AGAACGCAGCAGACCGCCGCGCCGTTGGCGAACTTGCTGGGGATGGCCCCGCAGGTATTG
CCCGGGCTCAACGAGATCCATGCCGGCATCTTCGAGGACCTGCCGCAGATCAGCCCCGCG
GGCCTGCTGTATCTCGTCGGCCCGATCGCCTGGACGCTCGGATTTCCCATCGTGCCGATG
CTGGCCCCGGGCTCCACCGACGTCAACGGGATCGTCTTCAACCGAGCCTTTACCGGTGCG
GTTCAAACGATCTACGACGCTTCCTTGGCCAATCCGGTCGTGGCCGCAGACGGCAACATC
ACGTCGGTCGCTTACTCCAGCGCATTCACCATCGGGGTCGGGACGATGATGAACGTCGAC
AATCCCCATCCGCTACTGCTGCTCACCCACCCGGTGCCCAACACCGGCGCCGTCGTGGTA
CAGGGCAATCCCGAGGGCGGCTGGACGCTGGTCAGCTGGGACGGGATACCCGTCGGGCCG
GCGTCGCTGCCGACCGCGTTATTCGTCGACGTGCGCGAGCTGATCACGGCGCCGCAATAT
GCGGCCTACGACATTTGGGAGTCCCTGTTCACCGGCGATCCGGCGGCGGTCATCAACGCG
GTGCGAGACGGTGCCGATGAGGTCGGCGCGGCTGTGGTCCAGTTCCCACATGCGGTGGCT
GACGACGTGATCGACGCTACGGGCCACCCCTATCTAAGCGGCCTGCCGATCGGTCTGCCC
AGCCTGATCCCATGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	PhysicalInteraction Rv1801	active	razeeth.new	2012-10-05
	authors,R. Riley,M. Pellegrini,D. Eisenberg Identifying cognate binding pairs among a large set of paralogs: the case of PE/PPE proteins of Mycobacterium tuberculosis. PLoS Comput. Biol. 2008
Interaction	RegulatedBy Rv3676	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv3676	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006