Rv0764c - cytochrome P450 51 cyp51


Protein Domains

Gene Information
LocusRv0764c
Symbolcyp51
Gene Namecytochrome P450 51 cyp51
Location856682 - 858037 (-)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:1356 bp
Protein:452 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number20606
Related GenesMAP0598c MAV_0708 Mkms_4670 Mmcs_4582 MSMEG_5863 MT0788 MUL_0473 Mvan_5161 nfa25890
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
Search for regulators of Rv0764c
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionPhysicalInteraction Rv0763cactiveamit.srcp2012-10-05
Structural Analysis
authors,KJ. McLean,AJ. Dunford,R. Neeli,MD. Driscoll,AW. Munro Structure, function and drug targeting in Mycobacterium tuberculosis cytochrome P450 systems. Arch. Biochem. Biophys. 2007
InteractionPhysicalInteraction Rv0763cactiveamit.srcp2012-10-05
Structural Analysis
A. Bellamine, AT. Mangla et al. Characterization and catalytic properties of the sterol 14alpha-demethylase from Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A. 1999
InteractionPhysicalInteraction Rv0763cactiveamit.srcp2012-10-05
Structural Analysis
JK. Capyk, R. Kalscheuer et al. Mycobacterial cytochrome p450 125 (cyp125) catalyzes the terminal hydroxylation of c27 steroids. J. Biol. Chem. 2009
InteractionPhysicalInteraction Rv0763cactiveamit.srcp2012-10-05
Structural Analysis
KJ. McLean, AJ. Warman et al. Biophysical characterization of the sterol demethylase P450 from Mycobacterium tuberculosis, its cognate ferredoxin, and their interactions. Biochemistry 2006
InteractionPhysicalInteraction Rv0763cactiveamit.srcp2012-10-05
Structural Analysis
CJ. Jackson, DC. Lamb et al. A novel sterol 14alpha-demethylase/ferredoxin fusion protein (MCCYP51FX) from Methylococcus capsulatus represents a new class of the cytochrome P450 superfamily. J. Biol. Chem. 2002
InteractionPhysicalInteraction Rv0763cactiveamit.srcp2012-10-05
Structural Analysis
KJ. McLean, AJ. Dunford et al. CYP121, CYP51 and associated redox systems in Mycobacterium tuberculosis: towards deconvoluting enzymology of P450 systems in a human pathogen. Biochem. Soc. Trans. 2006
InteractionPhysicalInteraction Rv0763cactiveamit.srcp2012-10-05
Spectrophotometric
authors,KJ. McLean,AJ. Dunford,R. Neeli,MD. Driscoll,AW. Munro Structure, function and drug targeting in Mycobacterium tuberculosis cytochrome P450 systems. Arch. Biochem. Biophys. 2007
InteractionPhysicalInteraction Rv0763cactiveamit.srcp2012-10-05
Spectrophotometric
A. Bellamine, AT. Mangla et al. Characterization and catalytic properties of the sterol 14alpha-demethylase from Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A. 1999
InteractionPhysicalInteraction Rv0763cactiveamit.srcp2012-10-05
Spectrophotometric
JK. Capyk, R. Kalscheuer et al. Mycobacterial cytochrome p450 125 (cyp125) catalyzes the terminal hydroxylation of c27 steroids. J. Biol. Chem. 2009
InteractionPhysicalInteraction Rv0763cactiveamit.srcp2012-10-05
Spectrophotometric
KJ. McLean, AJ. Warman et al. Biophysical characterization of the sterol demethylase P450 from Mycobacterium tuberculosis, its cognate ferredoxin, and their interactions. Biochemistry 2006
InteractionPhysicalInteraction Rv0763cactiveamit.srcp2012-10-05
Spectrophotometric
CJ. Jackson, DC. Lamb et al. A novel sterol 14alpha-demethylase/ferredoxin fusion protein (MCCYP51FX) from Methylococcus capsulatus represents a new class of the cytochrome P450 superfamily. J. Biol. Chem. 2002
InteractionPhysicalInteraction Rv0763cactiveamit.srcp2012-10-05
Spectrophotometric
KJ. McLean, AJ. Dunford et al. CYP121, CYP51 and associated redox systems in Mycobacterium tuberculosis: towards deconvoluting enzymology of P450 systems in a human pathogen. Biochem. Soc. Trans. 2006