Rv0819 - conserved hypothetical protein

Expression: Most Significant Conditions for Rv0819

Protein Domains

Gene Information
Locus	Rv0819
Symbol
Gene Name	conserved hypothetical protein
Location	911736 - 912683 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:948 bp Protein:316 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	19066
Related Genes	Acel_2026 CE2468 cg2847 DIP1911 jk0376 MAP0650 MAV_0761 Mkms_4611 ML2193 Mmcs_4524 MT0841 MUL_0436 Mvan_5096 nfa5990 SAV4058
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0819
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0819 Transcript 1
MTALDWRSALTADEQRSVRALVTATTAVDGVAPVGEQVLRELGQQRTEHLLVAGSRPGGP
IIGYLNLSPPRGAGGAMAELVVHPQSRRRGIGTAMARAALAKTAGRNQFWAHGTLDPARA
TASALGLVGVRELIQMRRPLRDIPEPTIPDGVVIRTYAGTSDDAELLRVNNAAFAGHPEQ
GGWTAVQLAERRGEAWFDPDGLILAFGDSPRERPGRLLGFHWTKVHPDHPGLGEVYVLGV
DPAAQRRGLGQMLTSIGIVSLARRLGGRKTLDPAVEPAVLLYVESDNVAAVRTYQSLGFT
TYSVDTAYALAGTDN*

Genomic Sequence

>Rv0819
GTGACGGCGCTTGACTGGCGCTCCGCTCTGACCGCCGACGAGCAGCGCAGCGTGCGTGCA
CTGGTCACGGCGACAACAGCAGTCGATGGGGTAGCACCCGTGGGTGAACAGGTGCTGCGG
GAACTGGGCCAGCAACGCACCGAGCATCTGCTGGTGGCCGGTTCGCGACCGGGCGGCCCG
ATCATCGGCTACCTCAACCTCAGCCCACCCCGGGGCGCGGGTGGTGCGATGGCGGAGTTG
GTGGTGCATCCGCAGTCTCGACGGCGCGGTATCGGCACCGCCATGGCCCGCGCGGCATTG
GCCAAGACCGCCGGCCGCAACCAGTTCTGGGCGCACGGCACGCTGGATCCCGCTCGGGCG
ACCGCGTCCGCGCTGGGTCTGGTCGGCGTCCGCGAACTGATCCAGATGCGACGCCCGCTG
CGTGATATCCCCGAACCGACGATCCCCGACGGGGTGGTGATCCGCACCTACGCGGGCACG
TCCGACGACGCTGAGCTACTCCGGGTCAACAACGCCGCGTTCGCCGGACACCCGGAACAG
GGTGGGTGGACCGCGGTCCAGCTTGCCGAGCGGCGTGGCGAGGCGTGGTTCGATCCAGAC
GGCCTGATCTTGGCCTTCGGTGATTCGCCACGTGAACGGCCTGGCCGGTTGCTGGGTTTC
CATTGGACCAAAGTGCATCCCGATCACCCGGGATTGGGCGAGGTGTACGTGCTGGGCGTC
GATCCGGCGGCGCAGCGCCGCGGTCTCGGCCAGATGTTGACGTCGATCGGTATCGTCTCG
CTGGCCCGTCGGCTGGGCGGTCGGAAGACCCTCGACCCTGCGGTCGAACCCGCCGTGCTG
CTCTACGTGGAGTCGGACAATGTGGCGGCCGTGCGAACCTACCAGAGCCTGGGCTTCACC
ACCTACAGCGTCGATACCGCCTACGCGCTGGCTGGCACGGATAACTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Term	TBRXN:MSHS mycothiol synthase - ISS	active	njamshidi	2012-10-05
	see PMID: 12754249, 12930994, Cole et al text MW. Vetting, SL. Roderick et al. Crystal structure of mycothiol synthase (Rv0819) from Mycobacterium tuberculosis shows structural homology to the GNAT family of N-acetyltransferases. Protein Sci. 2003
Term	TBRXN:MSHS mycothiol synthase - ISS	active	njamshidi	2012-10-05
	see PMID: 12754249, 12930994, Cole et al text GL. Newton, T. Koledin et al. The glycosyltransferase gene encoding the enzyme catalyzing the first step of mycothiol biosynthesis (mshA). J. Bacteriol. 2003
Term	TBRXN:MSHS mycothiol synthase - IDA	active	njamshidi	2012-10-05
	see PMID: 12754249, 12930994, Cole et al text MW. Vetting, SL. Roderick et al. Crystal structure of mycothiol synthase (Rv0819) from Mycobacterium tuberculosis shows structural homology to the GNAT family of N-acetyltransferases. Protein Sci. 2003
Term	TBRXN:MSHS mycothiol synthase - IDA	active	njamshidi	2012-10-05
	see PMID: 12754249, 12930994, Cole et al text GL. Newton, T. Koledin et al. The glycosyltransferase gene encoding the enzyme catalyzing the first step of mycothiol biosynthesis (mshA). J. Bacteriol. 2003
Term	EC:2.3.1.189 Mycothiol synthase. - NR	active	extern:JZUCKER	2012-03-06
	Assay of protein purified to homogeneity MW. Vetting, SL. Roderick et al. Crystal structure of mycothiol synthase (Rv0819) from Mycobacterium tuberculosis shows structural homology to the GNAT family of N-acetyltransferases. Protein Sci. 2003
Other	EC:	active	jjmcfadden	2012-03-05
	Inferred from direct assay GL. Newton, T. Koledin et al. The glycosyltransferase gene encoding the enzyme catalyzing the first step of mycothiol biosynthesis (mshA). J. Bacteriol. 2003