Rv0867c - resuscitation-promoting factor rpfA
Protein Domains

Gene Information
LocusRv0867c
SymbolrpfA
Gene Nameresuscitation-promoting factor rpfA
Location964312 - 965535 (-)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:1224 bp
Protein:408 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number37340
Related GenesCE0894 cg0936 DIP0775 jk0416 MAP0805c MAV_0996 Mkms_4566 ML2151 Mmcs_4479 MSMEG_5700 MT0890 MT0894 MUL_0283 Mvan_5049 nfa6370 Rv0872c
Transcriptional Regulation
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Regulatory Network
Search for regulators of Rv0867c
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionTranscription Rv3676activejgalag2012-10-05
Band shift
M. Stapleton, I. Haq et al. Mycobacterium tuberculosis cAMP receptor protein (Rv3676) differs from the Escherichia coli paradigm in its cAMP binding and DNA binding properties and transcription activation properties. J. Biol. Chem. 2010
InteractionTranscription Rv3676activejgalag2012-10-05
Band shift
G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
InteractionRegulatory Rv2389cactivesourish102012-10-05
Co-expression (Functional linkage)
KJ. Downing, JC. Betts et al. Global expression profiling of strains harbouring null mutations reveals that the five rpf-like genes of Mycobacterium tuberculosis show functional redundancy. Tuberculosis (Edinburgh, Scotland) 2004
InteractionPhysicalInteraction Rv1477activegirishgene072012-10-05
Affinity purification (Physical interaction)
S. Bardarov, S. Bardarov Jr et al. Specialized transduction: an efficient method for generating marked and unmarked targeted gene disruptions in Mycobacterium tuberculosis, M. bovis BCG and M. smegmatis. Microbiology (Reading, Engl.) 2002
InteractionPhysicalInteraction Rv1477activegirishgene072012-10-05
Affinity purification (Physical interaction)
EC. Hett, MC. Chao et al. A mycobacterial enzyme essential for cell division synergizes with resuscitation-promoting factor. PLoS Pathog. 2008
InteractionPhysicalInteraction Rv1477activegirishgene072012-10-05
Affinity purification (Physical interaction)
BD. Kana, BG. Gordhan et al. The resuscitation-promoting factors of Mycobacterium tuberculosis are required for virulence and resuscitation from dormancy but are collectively dispensable for growth in vitro. Mol. Microbiol. 2008
InteractionRegulatory Rv0616cactiveakankshajain.212012-10-05
Co-expression (Functional linkage)
T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003
InteractionRegulatedBy Rv3676activeyamir.moreno2012-10-05
Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support.
G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
InteractionRegulatedBy Rv0491activeyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003
NameResuscitation-promoting factoractivemjackson2012-10-05
Peptidoglycan turnover