Rv0931c - transmembrane serine/threonine-protein kinase D pknD

Expression: Most Significant Conditions for Rv0931c

Protein Domains

Gene Information
Locus	Rv0931c
Symbol	pknD
Gene Name	transmembrane serine/threonine-protein kinase D pknD
Location	1037920 - 1039914 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1995 bp Protein:665 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	37204
Related Genes	DIP0674 MAP3387c MAV_4238 MT0958 Mvan_4693
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0931c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0931c Transcript 1
MSDAVPQVGSQFGPYQLLRLLGRGGMGEVYEAEDTRKHRVVALKLISPQYSDNAVFRARM
QREADTAGRLTEPHIVPIHDYGEINGQFFVEMRMIDGTSLRALLKQYGPLTPARAVAIVR
QIAAALDAAHANGVTHRDVKPENILVTASDFAYLVDFGIARAASDPGLTQTGTAVGTYNY
MAPERFTGDEVTYRADIYALACVLGECLTGAPPYRADSVERLIAAHLMDPAPQPSQLRPG
RVPPALDQVIAKGMAKNPAERFMSAGDLAIAAHDALTTSEQHQATTILRRGDNATLLATP
ADTGLSQSESGIAGAGTGPPTPGAARWSPGDSATVAGPLAADSRGGNWPSQTGHSPAVPN
ALQASLGHAVPPAGNKRKVWAVVGAAAIVLVAIVAAAGYLVLRPSWSPTQASGQTVLPFT
GIDFRLSPSGVAVDSAGNVYVTSEGMYGRVVKLATGSTGTTVLPFNGLYQPQGLAVDGAG
TVYVTDFNNRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQGAVYVADRGNNRVVKLAAGS
KTQTVLPFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKLEAESNNQVVLPFTDITAPWGIA
VDEAGTVYVTEHNTNQVVKLLAGSTTSTVLPFTGLNTPLAVAVDSDRTVYVADRGNDRVV
KLTS*

Genomic Sequence

>Rv0931c
GTGAGCGATGCCGTTCCGCAGGTAGGGTCGCAATTTGGGCCGTATCAGCTATTGCGGCTG
CTGGGCCGAGGCGGGATGGGCGAGGTTTATGAGGCCGAGGACACCCGCAAGCACCGGGTG
GTGGCGCTGAAGTTGATCTCGCCGCAGTACTCCGACAATGCGGTGTTTCGAGCACGGATG
CAACGCGAGGCCGACACCGCGGGACGGCTGACCGAGCCACACATCGTGCCGATCCATGAC
TACGGCGAGATCAACGGACAGTTCTTTGTCGAAATGCGCATGATCGACGGCACCTCTTTA
CGCGCCCTATTGAAACAGTATGGTCCGCTGACCCCGGCCCGAGCTGTGGCCATCGTGCGC
CAGATCGCCGCCGCTTTGGATGCCGCGCATGCCAACGGCGTAACGCACCGCGACGTAAAA
CCGGAAAACATTCTGGTCACCGCGAGCGACTTCGCCTATCTGGTCGATTTCGGTATTGCC
CGTGCCGCCTCCGACCCGGGGCTGACCCAGACCGGGACCGCCGTGGGAACCTACAACTAC
ATGGCCCCGGAGCGGTTCACCGGCGATGAGGTCACCTATCGCGCAGATATCTATGCGTTG
GCGTGCGTGTTGGGTGAGTGTTTGACCGGTGCCCCACCGTATCGGGCCGACAGCGTTGAG
CGGTTGATCGCCGCGCATCTAATGGACCCTGCCCCGCAGCCCAGCCAGCTACGGCCCGGG
CGCGTGCCGCCGGCCCTGGATCAGGTGATCGCCAAAGGCATGGCCAAAAACCCCGCGGAG
CGCTTTATGAGCGCTGGTGATCTGGCCATCGCCGCCCATGACGCACTCACCACATCCGAG
CAACACCAGGCCACGACGATTCTGCGGCGCGGTGACAACGCAACCTTGCTGGCCACTCCG
GCCGATACGGGCTTGAGCCAGTCCGAGTCCGGCATTGCCGGGGCGGGCACCGGCCCACCG
ACCCCGGGTGCTGCCCGATGGTCGCCCGGGGACTCCGCGACCGTGGCCGGACCCCTGGCA
GCGGACAGCCGCGGCGGGAACTGGCCCAGCCAAACCGGACACTCCCCTGCCGTCCCGAAT
GCGCTCCAGGCCTCCCTGGGACACGCTGTGCCGCCGGCCGGCAACAAACGGAAGGTGTGG
GCCGTCGTCGGCGCTGCCGCGATCGTACTGGTGGCCATCGTCGCCGCCGCCGGCTACCTG
GTCTTACGACCTTCGTGGTCGCCGACGCAGGCATCCGGACAGACCGTGTTGCCGTTCACC
GGCATCGACTTCCGCCTCTCGCCGAGTGGGGTGGCAGTGGACAGCGCCGGCAACGTGTAC
GTCACCAGTGAGGGCATGTACGGCCGAGTGGTCAAGTTGGCCACCGGGTCAACCGGCACG
ACGGTGTTACCGTTCAACGGGCTGTACCAGCCGCAGGGGTTGGCGGTGGACGGCGCTGGC
ACCGTATACGTCACCGATTTCAACAACCGGGTGGTGACGTTAGCGGCCGGGTCCAACAAC
CAGACCGTGCTACCGTTCGACGGCCTCAACTACCCCGAAGGTCTCGCGGTGGATACCCAG
GGTGCGGTATACGTCGCCGACCGGGGCAACAACAGGGTGGTGAAGTTGGCGGCCGGATCC
AAGACCCAGACCGTGCTGCCGTTCACCGGCCTCAACGACCCCGACGGGGTGGCCGTCGAC
AACTCCGGCAACGTCTATGTCACCGACACCGACAACAACAGGGTTGTCAAGCTAGAGGCC
GAGTCGAATAACCAGGTCGTGCTGCCATTCACGGATATCACCGCACCGTGGGGCATCGCG
GTGGACGAAGCCGGAACCGTCTACGTCACCGAGCACAACACAAACCAGGTGGTCAAACTC
CTGGCCGGGTCGACCACCTCGACAGTGCTACCGTTCACCGGCCTCAACACCCCCCTCGCG
GTGGCAGTGGACAGCGACCGGACCGTCTACGTCGCCGACCGCGGCAACGACCGAGTGGTG
AAACTCACGTCATAA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Signaling Rv0516c	active	priyadarshinipriyanka2001	2012-10-05
	spectrophotometric Analysis AE. Greenstein, JA. MacGurn et al. M. tuberculosis Ser/Thr protein kinase D phosphorylates an anti-anti-sigma factor homolog. PLoS Pathog. 2007
Interaction	Signaling Rv0020c	active	priyadarshinipriyanka2001	2012-10-05
	Affinity purification (Physical interaction) C. Grundner, LM. Gay et al. Mycobacterium tuberculosis serine/threonine kinases PknB, PknD, PknE, and PknF phosphorylate multiple FHA domains. Protein Sci. 2005
Interaction	Signaling Rv1747	active	priyadarshinipriyanka2001	2012-10-05
	Affinity purification (Physical interaction) C. Grundner, LM. Gay et al. Mycobacterium tuberculosis serine/threonine kinases PknB, PknD, PknE, and PknF phosphorylate multiple FHA domains. Protein Sci. 2005
Interaction	Signaling Rv2942	active	priyadarshinipriyanka2001	2012-10-05
	spectrophotometric Analysis J. Pérez, R. Garcia et al. Mycobacterium tuberculosis transporter MmpL7 is a potential substrate for kinase PknD. Biochem. Biophys. Res. Commun. 2006
Interaction	Regulatory Rv0516c	active	shahanup86	2012-10-05
	Affinity purification (Physical interaction) AE. Greenstein, JA. MacGurn et al. M. tuberculosis Ser/Thr protein kinase D phosphorylates an anti-anti-sigma factor homolog. PLoS Pathog. 2007
Interaction	Signaling Rv0020c	active	vmevada102	2012-10-05
	Affinity purification (Physical interaction) C. Grundner, LM. Gay et al. Mycobacterium tuberculosis serine/threonine kinases PknB, PknD, PknE, and PknF phosphorylate multiple FHA domains. Protein Sci. 2005