Rv0952 - succinyl-CoA synthetase alpha chain sucD
Protein Domains

Gene Information
LocusRv0952
SymbolsucD
Gene Namesuccinyl-CoA synthetase alpha chain sucD
Location1063140 - 1064051 (+)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:912 bp
Protein:304 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number32717
Related GenesAcel_0381 BL0733 CE2449 cg2836 MAP0897 MAV_1075 Mkms_4412 ML0156 Mmcs_4326 MSMEG_5524 MT0979 MUL_4719 Mvan_4869 nfa49900 PPA1754 SAV3451
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
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Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionRegulatedBy Rv1221activeyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
R. Manganelli, MI. Voskuil et al. The Mycobacterium tuberculosis ECF sigma factor sigmaE: role in global gene expression and survival in macrophages. Mol. Microbiol. 2001
InteractionRegulatedBy Rv3676activeyamir.moreno2012-10-05
E.coli orthology based inference. Orthologous pair regulator-target found in E.coli.
G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
InteractionRegulatedBy Rv3676activeyamir.moreno2012-10-05
E.coli orthology based inference. Orthologous pair regulator-target found in E.coli.
authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006
TermEC:6.2.1.5 Succinate--CoA ligase (ADP-forming). - NRactiveextern:JZUCKER2012-03-06
Inferred from mutant phenotype
AD. Baughn, SJ. Garforth et al. An anaerobic-type alpha-ketoglutarate ferredoxin oxidoreductase completes the oxidative tricarboxylic acid cycle of Mycobacterium tuberculosis. PLoS Pathog. 2009
TermEC:6.2.1.5 Succinate--CoA ligase (ADP-forming). - NRactiveextern:JZUCKER2012-03-06
Traceable author statement to experimental support
authors,KY. Rhee,LP. de Carvalho,R. Bryk,S. Ehrt,J. Marrero,SW. Park,D. Schnappinger,A. Venugopal,C. Nathan Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier. Trends Microbiol. 2011