Rv1039c - PPE family protein

Expression: Most Significant Conditions for Rv1039c

Protein Domains

Gene Information
Locus	Rv1039c
Symbol	PPE15
Gene Name	PPE family protein
Location	1161297 - 1162472 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1176 bp Protein:392 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	13510
Related Genes	MT1068 MUL_4621
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1039c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1039c Transcript 1
MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP
ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL
VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA
AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT
PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA
DSVTPAGLGASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGMM
PGMASAAKGTGAYAGPRYGFKPTVMPKQVVV*

Genomic Sequence

>Rv1039c
ATGGATTTCGGAGCTTTACCCCCTGAGATCAACTCCGCACGCATGTACGCCGGCGCGGGT
GCAGGACCGATGATGGCCGCCGGGGCCGCATGGAACGGCCTGGCCGCCGAGTTGGGTACG
ACGGCCGCGTCGTATGAGTCGGTGATCACCCGGCTGACCACCGAGTCGTGGATGGGTCCG
GCCTCGATGGCGATGGTCGCCGCAGCCCAGCCCTATCTGGCTTGGTTGACCTACACCGCC
GAAGCCGCTGCGCATGCCGGCTCGCAGGCCATGGCGTCGGCGGCCGCCTACGAGGCGGCC
TATGCGATGACAGTGCCGCCGGAGGTGGTCGCGGCCAACCGGGCGCTGCTGGCGGCCCTG
GTCGCGACGAACGTCCTGGGGATCAACACACCGGCAATCATGGCGACCGAAGCCCTCTAT
GCCGAGATGTGGGCTCAGGACGCTCTGGCTATGTACGGCTACGCGGCCGCTTCGGGAGCC
GCCGGGATGCTGCAACCGTTAAGCCCGCCGTCGCAGACCACCAACCCGGGCGGGCTGGCC
GCCCAGTCCGCCGCGGTCGGCTCGGCTGCCGCCACCGCCGCCGTCAACCAGGTGAGCGTA
GCGGACCTGATCAGTAGCCTGCCCAACGCGGTGAGTGGGCTCGCCTCCCCAGTCACATCG
GTTCTCGACTCGACGGGGCTGAGCGGAATCATTGCCGACATCGACGCCCTGCTCGCGACC
CCGTTCGTGGCAAACATCATCAACAGCGCAGTCAACACCGCCGCTTGGTATGTCAACGCC
GCCATCCCCACCGCGATATTCCTAGCAAATGCCCTGAACAGTGGGGCGCCGGTAGCGATC
GCCGAAGGCGCCATCGAGGCTGCCGAGGGTGCCGCCAGTGCGGCCGCCGCGGGGTTGGCG
GACTCGGTGACGCCAGCGGGGCTCGGCGCAAGTTTAGGCGAGGCCACCCTGGTCGGCCGG
CTGTCAGTGCCGGCGGCCTGGTCTACGGCCGCACCGGCGACAACCGCCGGCGCCACAGCG
CTCGAAGGCAGCGGCTGGACCGTCGCCGCCGAAGAAGCCGGCCCAGTTACCGGGATGATG
CCGGGAATGGCCTCGGCCGCCAAGGGCACCGGTGCCTATGCCGGGCCGCGGTACGGATTC
AAGCCCACTGTCATGCCCAAACAGGTCGTCGTGTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	PhysicalInteraction Rv1040c	active	raj252000	2012-10-05
	Operon (Functional linkage) authors,R. Riley,M. Pellegrini,D. Eisenberg Identifying cognate binding pairs among a large set of paralogs: the case of PE/PPE proteins of Mycobacterium tuberculosis. PLoS Comput. Biol. 2008
Interaction	PhysicalInteraction Rv1040c	active	raj252000	2012-10-05
	Operon (Functional linkage) authors,NC. Gey van Pittius,SL. Sampson,H. Lee,Y. Kim,PD. van Helden,RM. Warren Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions. BMC Evol. Biol. 2006
Interaction	PhysicalInteraction Rv2769c	active	raj252000	2012-10-05
	Co-expression (Functional linkage) authors,R. Riley,M. Pellegrini,D. Eisenberg Identifying cognate binding pairs among a large set of paralogs: the case of PE/PPE proteins of Mycobacterium tuberculosis. PLoS Comput. Biol. 2008
Interaction	RegulatedBy Rv0757	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. SB. Walters, E. Dubnau et al. The Mycobacterium tuberculosis PhoPR two-component system regulates genes essential for virulence and complex lipid biosynthesis. Mol. Microbiol. 2006