Rv1327c - glucanase glgE

Expression: Most Significant Conditions for Rv1327c

Protein Domains

Gene Information
Locus	Rv1327c
Symbol	glgE
Gene Name	glucanase glgE
Location	1492320 - 1494425 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:2106 bp Protein:702 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	28325
Related Genes	Acel_0679 BL0388 CE1324 cg1382 DIP1066 jk1329 MAP2433 MAV_1547 Mkms_3934 Mmcs_3860 MSMEG_4916 MT1369 MUL_3935 Mvan_4301 nfa10790 PPA1114 SAV2802 SAV7395 SCO5443 SCO7335
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1327c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1327c Transcript 1
MSGRAIGTETEWWVPGRVEIDDVAPVVSCGVYPAKAVVGEVVPVSAAVWREGHEAVAATL
VVRYLGVRYPHLTDRPRARVLPTPSEPQQRVKPLLIPMTSGQEPFVFHGQFTPDRVGLWT
FRVDGWGDPIHTWRHGLIAKLDAGQGETELSNDLLVGAVLLERAATGVPRGLRDPLLAAA
AALRTPGDPVTRTALALTPEIEELLADYPLRDLVTRGEQFGVWVDRPLARFGAWYEMFPR
STGGWDDDGNPVHGTFATAAAELPRIAGMGFDVVYLPPIHPIGKVHRKGRNNSPTAAPTD
VGSPWAIGSDEGGHDTVHPSLGTIDDFDDFVSAARDLGMEVALDLALQCAPDHPWAREHR
QWFTELPDGTIAYAENPPKKYQDIYPLNFDNDPEGLYDEVLRVVQHWVNHGVKFFRVDNP
HTKPPNFWAWLIAQVKTVDPDVLFLSEAFTPPARQYGLAKLGFTQSYSYFTWRTTKWELT
EFGNQIAELADYRRPNLFVNTPDILHAVLQHNGPGMFAIRAVLAATMSPAWGMYCGYELF
EHRAVREGSEEYLDSEKYELRPRDFASALDQGRSLQPFITRLNIIRRLHPAFQQLRTIHF
HHVDNDALLAYSKFDPATGDCVLVVVTLNAFGPEEATLWLDMAALGMEDYDRFWVRDEIT
GEEYQWGQANYIRIDPARAVAHIINMPAVPYESRNTLLRRR*

Genomic Sequence

>Rv1327c
GTGAGTGGCCGGGCAATCGGAACGGAAACGGAGTGGTGGGTGCCCGGTCGTGTCGAAATC
GATGACGTCGCGCCCGTCGTTTCGTGCGGCGTATATCCCGCCAAGGCGGTGGTCGGCGAG
GTGGTCCCGGTCAGCGCGGCGGTCTGGCGTGAAGGCCACGAGGCCGTCGCAGCGACGCTG
GTCGTGCGCTACCTCGGAGTGCGTTACCCACACCTCACCGACAGACCCCGGGCCAGGGTG
CTTCCGACGCCGAGCGAGCCCCAACAACGCGTCAAGCCGCTGCTGATCCCGATGACGAGC
GGCCAGGAGCCCTTCGTTTTCCACGGCCAGTTCACCCCCGACCGGGTCGGATTGTGGACC
TTCCGGGTGGATGGTTGGGGTGACCCGATCCACACCTGGCGCCATGGGCTGATAGCCAAG
CTAGATGCCGGCCAGGGAGAGACCGAGCTGTCCAACGACCTGTTGGTAGGCGCGGTGCTG
TTGGAGCGCGCGGCGACCGGTGTGCCGCGCGGGTTACGCGATCCCCTCCTGGCGGCCGCG
GCAGCGCTGCGGACCCCCGGTGACCCGGTGACCCGCACCGCGTTGGCCCTGACACCGGAA
ATCGAAGAGCTGCTGGCCGACTATCCGCTGCGGGACCTGGTCACCCGGGGCGAGCAATTC
GGCGTCTGGGTGGATCGGCCGTTGGCCCGGTTCGGCGCTTGGTATGAGATGTTTCCGCGC
TCAACCGGCGGGTGGGACGACGACGGCAACCCGGTACACGGCACCTTCGCCACCGCTGCG
GCAGAACTTCCGCGCATCGCCGGCATGGGGTTCGACGTGGTGTACCTGCCGCCGATCCAT
CCAATTGGCAAGGTGCATCGCAAGGGTCGCAACAACTCGCCCACCGCCGCACCGACAGAC
GTGGGATCGCCGTGGGCGATCGGTAGCGATGAGGGCGGTCACGATACCGTTCATCCCAGC
CTGGGCACCATCGACGACTTCGACGACTTCGTCTCCGCGGCACGCGATCTGGGCATGGAG
GTCGCGCTGGACCTGGCGCTGCAATGCGCACCGGATCATCCGTGGGCCCGCGAACACCGG
CAGTGGTTCACCGAGCTGCCGGACGGCACCATCGCCTACGCGGAGAATCCACCGAAGAAG
TACCAGGACATCTATCCGCTCAACTTCGACAACGATCCCGAGGGCCTGTACGACGAAGTG
CTGCGCGTGGTGCAACATTGGGTTAACCACGGCGTCAAGTTCTTTCGCGTCGACAATCCC
CACACCAAACCACCCAACTTCTGGGCCTGGCTGATCGCGCAGGTGAAGACCGTCGACCCC
GACGTGCTGTTCCTGTCCGAGGCTTTCACCCCGCCCGCCCGCCAGTACGGGCTGGCCAAG
CTCGGCTTCACGCAGTCCTACAGCTATTTCACCTGGCGCACGACCAAGTGGGAGCTCACC
GAATTCGGCAACCAGATAGCCGAACTCGCCGACTACCGTCGGCCCAACCTGTTCGTCAAC
ACCCCGGACATCCTGCACGCGGTGCTGCAGCACAACGGTCCAGGCATGTTCGCCATCCGC
GCGGTGCTGGCCGCCACCATGAGCCCAGCCTGGGGGATGTACTGCGGTTATGAGCTTTTC
GAGCACCGTGCGGTGCGCGAGGGCAGCGAGGAGTACCTGGACTCGGAGAAGTACGAATTG
CGTCCCCGCGACTTTGCCAGCGCGCTGGACCAGGGTAGATCTTTGCAGCCGTTCATCACA
CGGCTCAATATAATTCGCCGGCTGCACCCGGCGTTTCAACAGTTGCGTACCATTCATTTT
CACCACGTTGACAACGACGCGTTGCTGGCCTACAGCAAGTTCGACCCGGCCACCGGCGAC
TGCGTGTTGGTGGTGGTGACACTCAACGCATTTGGTCCTGAAGAAGCTACGCTGTGGTTG
GACATGGCGGCGTTGGGCATGGAGGACTACGACCGGTTTTGGGTGCGCGACGAGATAACC
GGCGAAGAATACCAATGGGGGCAAGCCAATTACATCCGCATCGACCCAGCACGGGCAGTC
GCCCACATCATCAACATGCCAGCCGTGCCCTACGAGAGCCGAAACACGCTGCTGCGCAGG
AGGTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Name	alpha-1,4-glucan:maltose-1-P maltosyltransferase	active	mjackson	2012-10-05
	Other (lipo)polysaccharides [Methylglucose lipolysaccharides, glycogen and capsular alpha-1,4 glucan]
Name	alpha-1,4-glucan:maltose-1-P maltosyltransferase	active	mjackson	2012-10-05
	Other (lipo)polysaccharides [Methylglucose lipolysaccharides, glycogen and capsular alpha-1,4 glucan]
Term	EC:2.4.1.21 Starch synthase. - NR	active	extern:JZUCKER	2012-03-06
	Assay of protein purified to homogeneity from a heterlogous host R. Kalscheuer,K. Syson,U. Veeraraghavan,B. Weinrick,KE. Biermann,Z. Liu,JC. Sacchettini,G. Besra,S. Bornemann,WR. Jacobs Self-poisoning of Mycobacterium tuberculosis by targeting GlgE in an alpha-glucan pathway. Nature chemical biology 2010
Other	TBPWY:(MGLP and alpha-1,4 glucans)	active	mjackson	2012-03-05
	alpha-1,4-glucan:maltose-1-P maltosyltransferase (phenotypic [mycobacterial recombinant strains]; enzymatic) R. Kalscheuer,K. Syson,U. Veeraraghavan,B. Weinrick,KE. Biermann,Z. Liu,JC. Sacchettini,G. Besra,S. Bornemann,WR. Jacobs Self-poisoning of Mycobacterium tuberculosis by targeting GlgE in an alpha-glucan pathway. Nature chemical biology 2010
Other	TBPWY:(MGLP and alpha-1,4 glucans)	active	mjackson	2012-03-05
	alpha-1,4-glucan:maltose-1-P maltosyltransferase (phenotypic [mycobacterial recombinant strains]; enzymatic) authors,AD. Elbein,I. Pastuszak,AJ. Tackett,T. Wilson,YT. Pan Last step in the conversion of trehalose to glycogen: a mycobacterial enzyme that transfers maltose from maltose 1-phosphate to glycogen. J. Biol. Chem. 2010