Rv1364c - conserved hypothetical protein

Expression: Most Significant Conditions for Rv1364c

Protein Domains

Gene Information
Locus	Rv1364c
Symbol
Gene Name	conserved hypothetical protein
Location	1535683 - 1537644 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1962 bp Protein:654 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	26880
Related Genes	cg1179 MAP2361 MAP2511 MAP2512 MAV_1410 MAV_1619 ML1750 ML1752 MT1397 MT1400 MT1410 MUL_3853 Mvan_2109 Rv1354c Rv1357c
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1364c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1364c Transcript 1
MAAEMDWDKTVGAAEDVRRIFEHIPAILVGLEGPDHRFVAVNAAYRGFSPLLDTVGQPAR
EVYPELEGQQIYEMLDRVYQTGEPQSGSEWRLQTDYDGSGVEERYFDFVVTPRRRADGSI
EGVQLIVDDVTSRVRARQAAEARVEELSERYRNVRDSATVMQQALLAASVPVVPGADIAA
EYLVAAEDTAAGGDWFDALALGDRLVLVVGDVVGHGVEAAAVMSQLRTALRMQISAGYTV
VEALEAVDRFHKQVPGSKSATMCVGSLDFTSGEFQYCTAGHPPPLLVTADASARYVEPTG
AGPLGSGTGFPVRSEVLNIGDAILFYTDGLIERPGRPLEASTAEFADLAASIASGSGGFV
LDAPARPIDRLCSDTLELLLRSTGYNDDVTLLAMQRRAPTPPLHITLDATINAARTVRAQ
LREWLAEIGADHSDIADIVHAISEFVENAVEHGYATDVSKGIVVAAALAGDGNVRASVID
RGQWKDHRDGARGRGRGLAMAEALVSEARIMHGAGGTTATLTHRLSRPARFVTDTMVRRA
AFQQTIDSEFVSLVESGRIVVRGDVDSTTAATLDRQIAVESRSGIAPVTIDLSAVTHLGS
AGVGALAAACDRARKQGTECVLVAPPGSPAHHVLSLVQLPVVGADTEDIFAQE*

Genomic Sequence

>Rv1364c
ATGGCGGCCGAAATGGACTGGGACAAAACGGTCGGTGCGGCCGAGGATGTACGACGCATT
TTCGAGCACATCCCTGCGATTCTGGTTGGCCTCGAGGGGCCTGACCATCGCTTTGTCGCA
GTGAACGCGGCCTATCGCGGCTTCAGTCCATTGCTTGACACCGTGGGACAGCCCGCTCGG
GAGGTCTATCCCGAACTGGAGGGTCAGCAGATCTACGAAATGTTGGACCGGGTCTATCAA
ACCGGTGAGCCGCAATCAGGATCGGAGTGGCGACTACAAACTGATTACGACGGTTCCGGA
GTTGAGGAACGATACTTCGACTTTGTCGTCACACCGCGCCGCCGGGCGGACGGATCGATC
GAGGGCGTGCAGCTCATTGTGGACGACGTCACCAGCCGAGTGCGAGCCCGGCAGGCGGCC
GAGGCGCGCGTGGAGGAACTGTCCGAGCGCTATCGCAATGTGCGCGATTCAGCCACCGTT
ATGCAGCAGGCGTTGCTGGCCGCGTCGGTGCCCGTGGTTCCCGGCGCCGACATAGCCGCC
GAGTACCTGGTCGCCGCCGAGGATACCGCGGCCGGCGGCGACTGGTTCGACGCGCTGGCC
CTCGGGGATCGGTTGGTGCTCGTCGTTGGCGACGTCGTGGGCCACGGCGTGGAGGCCGCA
GCGGTCATGTCGCAATTACGTACGGCGTTACGCATGCAGATCTCGGCGGGGTACACGGTC
GTCGAGGCGCTTGAGGCAGTGGACCGCTTCCATAAACAGGTACCTGGATCGAAATCGGCC
ACCATGTGTGTCGGCTCGCTCGACTTCACCTCGGGCGAATTCCAGTACTGCACAGCCGGA
CACCCGCCACCGCTGCTGGTGACCGCGGACGCGAGTGCGCGGTATGTCGAACCAACCGGC
GCGGGTCCGCTCGGCAGCGGAACCGGATTTCCAGTGCGCAGTGAAGTGCTCAACATCGGC
GACGCGATCCTCTTTTACACTGACGGCCTGATCGAGCGGCCCGGTCGGCCGCTCGAGGCC
AGCACCGCCGAATTTGCCGACCTAGCGGCCAGCATCGCCAGCGGCAGTGGCGGCTTTGTG
CTCGACGCCCCGGCACGGCCCATCGACCGACTCTGTTCGGACACACTTGAATTGCTGCTG
CGGTCCACCGGCTACAACGACGATGTGACCCTGCTTGCGATGCAACGCCGGGCGCCAACG
CCGCCGCTGCACATAACGCTGGATGCGACGATCAACGCGGCACGAACCGTTCGAGCCCAG
CTTCGTGAGTGGCTGGCAGAGATCGGCGCCGACCACTCCGACATCGCCGATATCGTGCAC
GCGATCTCCGAATTCGTCGAGAACGCGGTCGAACACGGATACGCCACGGACGTCTCCAAG
GGCATCGTTGTCGCGGCCGCGCTGGCCGGCGACGGCAACGTGCGGGCATCGGTAATCGAC
CGGGGCCAATGGAAGGACCACCGCGACGGCGCCCGTGGCCGTGGGCGCGGCCTGGCGATG
GCCGAGGCCCTAGTGTCGGAGGCGCGCATCATGCATGGCGCCGGCGGAACGACTGCCACA
CTTACGCATCGCCTGTCGCGGCCGGCGCGGTTTGTCACCGACACGATGGTTCGCCGGGCA
GCTTTCCAACAAACCATCGACAGCGAATTCGTCTCCCTAGTTGAATCCGGCCGCATCGTT
GTCCGGGGCGACGTCGATTCGACCACCGCAGCCACATTGGACCGCCAGATCGCCGTCGAA
AGCCGTTCTGGCATAGCACCCGTGACGATCGACCTCAGTGCCGTCACCCACCTTGGTTCG
GCCGGCGTCGGCGCCCTCGCTGCCGCTTGTGACCGGGCACGCAAACAGGGGACCGAGTGC
GTGCTGGTGGCCCCACCCGGCAGCCCGGCGCACCATGTCTTGTCGCTGGTCCAGCTGCCC
GTTGTCGGCGCCGACACCGAGGACATCTTCGCCCAGGAGTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv3286c	active	hibeeluck	2012-10-05
	Co-expression (Functional linkage) authors,J. Beaucher,S. Rodrigue,PE. Jacques,I. Smith,R. Brzezinski,L. Gaudreau Novel Mycobacterium tuberculosis anti-sigma factor antagonists control sigmaF activity by distinct mechanisms. Mol. Microbiol. 2002
Interaction	Transcription Rv3286c	active	hibeeluck	2012-10-05
	Co-expression (Functional linkage) authors,J. Beaucher,S. Rodrigue,PE. Jacques,I. Smith,R. Brzezinski,L. Gaudreau Novel Mycobacterium tuberculosis anti-sigma factor antagonists control sigmaF activity by distinct mechanisms. Mol. Microbiol. 2002
Interaction	Regulatory Rv3286c	active	hibeeluck	2012-10-05
	Co-expression (Functional linkage) EP. Williams, JH. Lee et al. Mycobacterium tuberculosis SigF regulates genes encoding cell wall-associated proteins and directly regulates the transcriptional regulatory gene phoY1. J. Bacteriol. 2007
Interaction	Transcription Rv3286c	active	hibeeluck	2012-10-05
	Co-expression (Functional linkage) EP. Williams, JH. Lee et al. Mycobacterium tuberculosis SigF regulates genes encoding cell wall-associated proteins and directly regulates the transcriptional regulatory gene phoY1. J. Bacteriol. 2007
Interaction	Regulatory Rv3286c	active	hibeeluck	2012-10-05
	Co-expression (Functional linkage) S. Dhandayuthapani Stress response of genes encoding putative stress signaling molecules of Mycobacterium tuberculosis. Front. Biosci. 2007
Interaction	Transcription Rv3286c	active	hibeeluck	2012-10-05
	Co-expression (Functional linkage) S. Dhandayuthapani Stress response of genes encoding putative stress signaling molecules of Mycobacterium tuberculosis. Front. Biosci. 2007
Interaction	Signaling Rv1904	active	kaveri.verma	2012-10-05
	yeast two-hybrid system(functional linkage) BK. Parida, T. Douglas et al. Interactions of anti-sigma factor antagonists of Mycobacterium tuberculosis in the yeast two-hybrid system. Tuberculosis (Edinburgh, Scotland) null
Interaction	Regulatory Rv1904	active	jgalag	2012-10-05
	Yeast two-hybrid (Physical interaction) BK. Parida, T. Douglas et al. Interactions of anti-sigma factor antagonists of Mycobacterium tuberculosis in the yeast two-hybrid system. Tuberculosis (Edinburgh, Scotland) null
Interaction	Regulatory Rv3287c	active	swetha.r	2012-10-05
	authors,MS. Li,SJ. Waddell,IM. Monahan,JA. Mangan,SL. Martin,MJ. Everett,PD. Butcher Increased transcription of a potential sigma factor regulatory gene Rv1364c in Mycobacterium bovis BCG while residing in macrophages indicates use of alternative promoters. FEMS Microbiol. Lett. 2004
Interaction	Regulatory Rv3286c	active	swetha.r	2012-10-05
	authors,MS. Li,SJ. Waddell,IM. Monahan,JA. Mangan,SL. Martin,MJ. Everett,PD. Butcher Increased transcription of a potential sigma factor regulatory gene Rv1364c in Mycobacterium bovis BCG while residing in macrophages indicates use of alternative promoters. FEMS Microbiol. Lett. 2004
Interaction	Regulatory Rv3287c	active	swetha.r	2012-10-05
	authors,RK. Jaiswal,G. Manjeera,B. Gopal Role of a PAS sensor domain in the Mycobacterium tuberculosis transcription regulator Rv1364c. Biochemical and biophysical research communications 2010
Interaction	Regulatory Rv3286c	active	swetha.r	2012-10-05
	authors,RK. Jaiswal,G. Manjeera,B. Gopal Role of a PAS sensor domain in the Mycobacterium tuberculosis transcription regulator Rv1364c. Biochemical and biophysical research communications 2010
Interaction	Regulatory Rv3287c	active	swetha.r	2012-10-05
	P. Sachdeva, A. Narayan et al. Loss of kinase activity in Mycobacterium tuberculosis multidomain protein Rv1364c. FEBS J. 2008
Interaction	Regulatory Rv3286c	active	swetha.r	2012-10-05
	P. Sachdeva, A. Narayan et al. Loss of kinase activity in Mycobacterium tuberculosis multidomain protein Rv1364c. FEBS J. 2008