Rv1383 - carbamoyl-phosphate synthase small chain carA

Expression: Most Significant Conditions for Rv1383

Protein Domains

Gene Information
Locus	Rv1383
Symbol	carA
Gene Name	carbamoyl-phosphate synthase small chain carA
Location	1555971 - 1557101 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1131 bp Protein:377 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	30272
Related Genes	Acel_1299 BL0067 CE1730 cg1814 DIP1332 jk1023 MAP1118 MAV_3390 Mkms_2413 ML0535 Mmcs_2366 MSMEG_3046 MT1427 MUL_1783 Mvan_2663 nfa36200 PPA0999 SAV6866
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1383
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1383 Transcript 1
MSKAVLVLEDGRVFTGRPFGATGQALGEAVFSTGMSGYQETLTDPSYHRQIVVATAPQIG
NTGWNGEDSESRGERIWVAGYAVRDPSPRASNWRATGTLEDELIRQRIVGIAGIDTRAVV
RHLRSRGSMKAGVFSDGALAEPADLIARVRAQQSMLGADLAGEVSTAEPYVVEPDGPPGV
SRFTVAALDLGIKTNTPRNFARRGIRCHVLPASTTFEQIAELNPHGVFLSNGPGDPATAD
HVVALTREVLGAGIPLFGICFGNQILGRALGLSTYKMVFGHRGINIPVVDHATGRVAVTA
QNHGFALQGEAGQSFATPFGPAVVSHTCANDGVVEGVKLVDGRAFSVQYHPEAAAGPHDA
EYLFDQFVELMAGEGR*

Genomic Sequence

>Rv1383
TTGAGCAAAGCCGTATTGGTCCTCGAAGACGGCCGGGTGTTCACCGGCAGGCCGTTCGGC
GCGACCGGACAAGCGCTCGGGGAGGCCGTGTTTTCCACCGGCATGTCCGGTTATCAGGAG
ACGCTGACCGATCCCAGCTATCACCGTCAGATCGTGGTGGCCACCGCGCCGCAGATCGGC
AACACCGGCTGGAACGGCGAGGACTCCGAAAGCCGAGGGGAGCGGATCTGGGTCGCCGGT
TACGCGGTGCGCGACCCGTCGCCGCGCGCGTCCAACTGGCGCGCCACCGGCACGTTGGAA
GACGAACTCATCCGCCAGCGCATCGTCGGGATCGCCGGCATCGACACCCGGGCCGTGGTG
CGCCATCTGCGCAGCCGCGGGTCGATGAAGGCGGGGGTGTTCTCCGACGGGGCGCTGGCC
GAGCCTGCCGACTTGATCGCGCGGGTGCGAGCACAACAGTCGATGCTGGGCGCCGATCTG
GCCGGCGAGGTCAGCACCGCGGAGCCGTATGTCGTCGAACCCGACGGGCCACCGGGTGTT
TCGAGGTTCACCGTGGCCGCCCTAGATCTTGGTATCAAGACCAACACTCCGCGTAACTTC
GCCCGGCGCGGGATTCGCTGCCATGTGCTGCCGGCATCGACCACCTTCGAGCAGATCGCC
GAACTCAACCCGCATGGCGTGTTCTTGTCCAACGGCCCCGGCGACCCGGCCACCGCCGAT
CACGTCGTCGCGCTTACCCGCGAGGTGCTGGGCGCCGGAATCCCGTTGTTCGGCATCTGT
TTCGGCAACCAGATCCTGGGCCGCGCGCTGGGCCTGTCGACCTACAAGATGGTGTTTGGG
CACCGCGGCATCAACATCCCGGTCGTCGACCACGCCACCGGTCGGGTGGCGGTGACCGCG
CAAAACCATGGCTTCGCCCTTCAGGGGGAGGCGGGCCAATCCTTCGCCACCCCGTTCGGT
CCCGCGGTGGTCAGCCACACCTGCGCCAACGACGGTGTGGTCGAAGGCGTCAAGCTCGTT
GACGGGCGGGCGTTTTCGGTGCAATACCACCCGGAAGCCGCCGCCGGCCCGCACGATGCC
GAGTACCTGTTCGACCAGTTCGTGGAGCTGATGGCAGGGGAGGGCCGCTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv1379	active	yamir.moreno	2012-10-05
	Protein structure based inferences. the regulation is infered after the observation of protein structure. KA. Kantardjieff, C. Vasquez et al. Structure of pyrR (Rv1379) from Mycobacterium tuberculosis: a persistence gene and protein drug target. Acta Crystallogr. D Biol. Crystallogr. 2005
Interaction	RegulatedBy Rv1657	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv1657	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006
Term	EC:6.3.5.5 Carbamoyl-phosphate synthase (glutamine-hydrolyzing). - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay authors,P. Vaishnav,S. Randev,S. Jatiani,S. Aggarwal,H. Keharia,PR. Vyas,G. Nareshkumar,G. Archana Characterization of carbamoyl phosphate synthetase of Streptomyces spp. Indian J. Exp. Biol. 2000