Rv1473 - macrolide-transport ATP-binding protein ABC transporter

Expression: Most Significant Conditions for Rv1473

Protein Domains

Gene Information
Locus	Rv1473
Symbol
Gene Name	macrolide-transport ATP-binding protein ABC transporter
Location	1660656 - 1662284 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1629 bp Protein:543 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	35534
Related Genes	CE1678 cg1753 DIP1289 jk0977 MAP1198 MAV_3306 Mkms_2491 ML1816 Mmcs_2446 MSMEG_3140 MT1519 MUL_1481 Mvan_2742 nfa34880 PPA1538 SAV6426
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1473
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1473 Transcript 1
MITATDLEVRAGARILLAPDGPDLRVQPGDRIGLVGRNGAGKTTTLRILAGEVEPYAGSV
TRAGEIGYLPQDPKVGDLDVLARDRVLSARGLDVLLTDLEKQQALMAEVADEDERDRAIR
RYGQLEERFVALGGYGAESEAGRICASLGLPERVLTQRLRTLSGGQRRRVELARILFAAS
ESGAGNSTTLLLDEPTNHLDADSLGWLRDFLRLHTGGLVVISHNVDLVADVVNKVWFLDA
VRGQVDVYNMGWQRYVDARATDEQRRIRERANAERKAAALRAQAAKLGAKATKAVAAQNM
LRRADRMMAALDEERVADKVARIKFPTPAACGRTPLVANGLGKTYGSLEVFTGVDLAIDR
GSRVVILGLNGAGKTTLLRLLAGVEQPDTGVLEPGYGLRIGYFAQEHDTLDNDATVWENV
RHAAPDAGEQDLRGLLGAFMFTGPQLEQPAGTLSGGEKTRLALAGLVASTANVLLLDEPT
NNLDPASREQVLDALRSYRGAVVLVTHDPGAAAALGPQRVVLLPDGTEDYWSDEYRDLIE
LA*

Genomic Sequence

>Rv1473
GTGATCACAGCTACGGACCTCGAGGTCCGCGCTGGCGCGCGCATCCTGCTCGCACCCGAC
GGCCCCGACCTGCGTGTGCAGCCCGGCGATCGTATCGGGCTGGTCGGACGTAACGGTGCC
GGCAAGACCACCACGCTGCGCATTCTGGCGGGGGAGGTCGAACCCTATGCCGGGTCGGTT
ACCCGTGCCGGCGAAATCGGCTACCTGCCACAGGATCCCAAAGTTGGCGATCTCGACGTG
CTGGCCCGTGACCGGGTGCTGTCCGCCCGCGGACTGGACGTCCTGCTCACTGATCTGGAG
AAGCAGCAGGCGTTGATGGCCGAGGTCGCCGACGAGGACGAGCGTGACCGCGCCATCCGC
CGTTACGGTCAGCTCGAGGAGCGATTCGTCGCGCTGGGCGGCTATGGCGCCGAAAGCGAA
GCCGGCCGCATCTGCGCCAGCCTAGGCTTGCCCGAGCGGGTGCTGACCCAGCGGCTGCGT
ACCCTTTCCGGAGGTCAGCGCCGCCGGGTGGAACTAGCCCGCATTTTGTTCGCCGCGTCC
GAGAGTGGCGCTGGAAATTCCACCACCTTGTTGCTCGACGAGCCGACTAACCACCTCGAC
GCTGATTCGCTGGGCTGGCTGCGGGACTTCCTGCGCTTGCATACGGGCGGGCTGGTGGTC
ATCAGCCACAACGTGGACCTGGTGGCCGATGTCGTCAATAAAGTGTGGTTCCTGGATGCC
GTGCGCGGCCAGGTCGATGTTTACAACATGGGCTGGCAGCGCTACGTCGACGCTCGGGCC
ACCGACGAGCAACGTCGCATCCGGGAACGCGCTAACGCCGAACGCAAGGCGGCCGCGCTG
CGTGCACAGGCCGCCAAGTTGGGCGCCAAGGCCACCAAAGCCGTTGCGGCCCAGAACATG
TTGCGCCGCGCCGATCGGATGATGGCCGCACTCGACGAGGAGCGAGTCGCCGACAAGGTG
GCCCGGATCAAGTTCCCCACCCCGGCGGCGTGTGGACGCACACCGCTGGTGGCCAACGGT
CTGGGCAAGACGTATGGCTCGCTGGAAGTCTTCACCGGTGTCGACTTGGCCATCGACCGC
GGCTCGCGGGTGGTCATACTCGGACTCAACGGTGCCGGCAAGACCACGCTGCTGCGATTG
CTGGCCGGTGTCGAGCAGCCCGACACCGGAGTGCTGGAACCCGGATACGGTTTACGGATC
GGCTATTTCGCGCAGGAGCACGACACGCTCGACAACGATGCCACCGTTTGGGAGAACGTC
CGGCACGCGGCACCGGATGCCGGCGAACAGGACCTGCGCGGCCTGCTGGGTGCGTTCATG
TTCACCGGTCCGCAGCTCGAGCAGCCGGCCGGCACGCTCTCCGGCGGTGAGAAGACCCGG
CTCGCGCTGGCCGGCTTGGTGGCCTCCACCGCGAATGTGCTGCTGCTCGATGAACCGACC
AACAATCTCGATCCGGCCTCGCGCGAGCAGGTGCTCGACGCGCTGCGCAGCTACCGAGGT
GCGGTGGTGCTGGTGACGCATGATCCCGGGGCGGCCGCGGCGCTCGGTCCCCAACGGGTG
GTGCTGTTGCCCGACGGCACCGAGGACTACTGGTCCGACGAGTATCGAGATCTCATCGAG
CTGGCCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv3197A	active	priti.priety	2012-10-05
	Co-expression (Functional linkage) authors,F. Doucet-Populaire,K. Buriánková,J. Weiser,JL. Pernodet Natural and acquired macrolide resistance in mycobacteria. Curr Drug Targets Infect Disord 2002
Interaction	Regulatory Rv3197A	active	priti.priety	2012-10-05
	Co-expression (Functional linkage) RP. Morris, L. Nguyen et al. Ancestral antibiotic resistance in Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A. 2005
Interaction	Regulatory Rv3197A	active	priti.priety	2012-10-05
	Co-expression (Functional linkage) authors,M. Braibant,P. Gilot,J. Content The ATP binding cassette (ABC) transport systems of Mycobacterium tuberculosis. FEMS Microbiol. Rev. 2000