Rv1477 - invasion-associated protein

Expression: Most Significant Conditions for Rv1477

Protein Domains

Gene Information
Locus	Rv1477
Symbol
Gene Name	invasion-associated protein
Location	1666990 - 1668408 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1419 bp Protein:473 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	36048
Related Genes	MAP1203 MAP1204 MAV_3300 MAV_3301 Mkms_2496 Mkms_2497 ML1811 ML1812 Mmcs_2451 Mmcs_2452 MSMEG_3145 MSMEG_3146 MT1524 MT1525 MUL_1486 MUL_1487 Mvan_2747 Mvan_2748 nfa34810 Rv1478
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1477
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1477 Transcript 1
MRRNRRGSPARPAARFVRPAIPSALSVALLVCTPGLATADPQTDTIAALIADVAKANQRL
QDLSDEVQAEQESVNKAMVDVETARDNAAAAEDDLEVSQRAVKDANAAIAAAQHRFDTFA
AATYMNGPSVSYLSASSPDEIIATVTAAKTLSASSQAVMANLQRARTERVNTESAARLAK
QKADKAAADAKASQDAAVAALTETRRKFDEQREEVQRLAAERDAAQARLQAARLVAWSSE
GGQGAPPFRMWDPGSGPAGGRAWDGLWDPTLPMIPSANIPGDPIAVVNQVLGISATSAQV
TANMGRKFLEQLGILQPTDTGITNAPAGSAQGRIPRVYGRQASEYVIRRGMSQIGVPYSW
GGGNAAGPSKGIDSGAGTVGFDCSGLVLYSFAGVGIKLPHYSGSQYNLGRKIPSSQMRRG
DVIFYGPNGSQHVTIYLGNGQMLEAPDVGLKVRVAPVRTAGMTPYVVRYIEY*

Genomic Sequence

>Rv1477
ATGAGACGGAATCGCCGTGGCTCGCCAGCGCGACCGGCCGCACGGTTTGTCCGTCCGGCA
ATTCCGTCGGCTTTGAGTGTGGCCCTGCTGGTATGCACACCGGGGCTGGCTACCGCCGAT
CCACAGACGGACACCATCGCCGCGCTGATTGCCGACGTCGCCAAGGCCAACCAGCGCCTG
CAAGACCTGAGCGACGAGGTTCAGGCCGAACAGGAAAGCGTTAACAAGGCGATGGTCGAC
GTGGAAACCGCTCGGGACAACGCTGCCGCGGCCGAAGACGACCTGGAGGTCAGCCAGCGC
GCGGTTAAGGACGCCAACGCGGCGATCGCCGCGGCTCAGCACCGGTTCGACACCTTCGCG
GCGGCCACCTACATGAACGGTCCCTCGGTCAGCTACCTCAGCGCGAGCAGCCCCGACGAG
ATCATTGCCACTGTGACCGCCGCCAAGACCCTTAGCGCCAGTTCCCAAGCGGTGATGGCC
AACCTGCAGCGGGCCCGGACCGAGCGGGTGAACACGGAGTCGGCGGCGCGGCTAGCCAAG
CAGAAGGCTGATAAGGCCGCCGCCGACGCAAAGGCCAGCCAGGATGCCGCGGTGGCGGCG
CTCACCGAGACCCGGCGGAAGTTCGATGAACAGCGCGAGGAGGTCCAACGCCTGGCCGCC
GAGCGCGATGCGGCTCAAGCCCGACTGCAGGCGGCCAGGTTGGTTGCCTGGTCCTCGGAG
GGTGGTCAGGGTGCGCCGCCGTTCCGGATGTGGGATCCCGGATCGGGCCCTGCCGGTGGG
CGTGCATGGGATGGCTTGTGGGACCCCACGCTGCCCATGATCCCCAGCGCCAACATCCCC
GGCGACCCGATCGCGGTAGTGAACCAGGTGTTGGGGATCTCGGCAACGTCAGCGCAGGTC
ACCGCCAATATGGGGCGCAAGTTCCTGGAGCAGCTGGGCATCTTGCAGCCCACCGATACC
GGCATCACCAACGCTCCGGCGGGCTCGGCCCAGGGCCGGATTCCGCGAGTTTATGGGCGC
CAGGCTTCTGAATACGTGATCCGCCGCGGCATGTCACAGATCGGGGTGCCCTATTCCTGG
GGCGGCGGCAATGCCGCGGGCCCGAGCAAGGGCATCGACTCCGGGGCCGGCACCGTCGGC
TTCGACTGCTCAGGCCTGGTGTTGTACTCGTTTGCTGGGGTGGGCATCAAGCTGCCGCAC
TACTCGGGTTCGCAGTACAACCTGGGCCGCAAGATCCCGTCCTCGCAGATGCGCCGCGGC
GACGTCATCTTCTACGGCCCGAACGGTAGCCAGCACGTGACGATCTACCTCGGCAACGGC
CAGATGCTCGAGGCGCCCGACGTCGGTTTGAAGGTGCGGGTTGCGCCCGTGCGCACGGCT
GGCATGACCCCGTATGTGGTCCGATACATCGAGTACTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	PhysicalInteraction Rv2450c	active	singhpankaj2116	2012-10-05
	Co-expression (Functional linkage) authors,GV. Mukamolova,AS. Kaprelyants,DI. Young,M. Young,DB. Kell A bacterial cytokine. Proc. Natl. Acad. Sci. U.S.A. 1998
Interaction	PhysicalInteraction Rv2450c	active	singhpankaj2116	2012-10-05
	Co-expression (Functional linkage) EC. Hett, MC. Chao et al. A partner for the resuscitation-promoting factors of Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	PhysicalInteraction Rv2450c	active	singhpankaj2116	2012-10-05
	Co-expression (Functional linkage) BD. Kana, BG. Gordhan et al. The resuscitation-promoting factors of Mycobacterium tuberculosis are required for virulence and resuscitation from dormancy but are collectively dispensable for growth in vitro. Mol. Microbiol. 2008
Interaction	PhysicalInteraction Rv2450c	active	richasinha4u	2012-10-05
	Yeast two-hybrid (Physical interaction) EC. Hett, MC. Chao et al. A partner for the resuscitation-promoting factors of Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	PhysicalInteraction Rv2450c	active	richasinha4u	2012-10-05
	Yeast two-hybrid (Physical interaction) authors,JM. Tufariello,WR. Jacobs,J. Chan Individual Mycobacterium tuberculosis resuscitation-promoting factor homologues are dispensable for growth in vitro and in vivo. Infect. Immun. 2004
Interaction	PhysicalInteraction Rv2450c	active	richasinha4u	2012-10-05
	Yeast two-hybrid (Physical interaction) BD. Kana, BG. Gordhan et al. The resuscitation-promoting factors of Mycobacterium tuberculosis are required for virulence and resuscitation from dormancy but are collectively dispensable for growth in vitro. Mol. Microbiol. 2008
Interaction	PhysicalInteraction Rv2450c	active	richasinha4u	2012-10-05
	Yeast two-hybrid (Physical interaction) KJ. Downing, JC. Betts et al. Global expression profiling of strains harbouring null mutations reveals that the five rpf-like genes of Mycobacterium tuberculosis show functional redundancy. Tuberculosis (Edinburgh, Scotland) 2004
Interaction	Activates Rv2450c	active	vijayachitra	2012-10-05
	Yeast two-hybrid (Physical interaction) EC. Hett, MC. Chao et al. A partner for the resuscitation-promoting factors of Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	Activates Rv1009	active	vijayachitra	2012-10-05
	Yeast two-hybrid (Physical interaction) EC. Hett, MC. Chao et al. A partner for the resuscitation-promoting factors of Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	PhysicalInteraction Rv1009	active	harsharohiratruefriend	2012-10-05
	yeast two hybrid BD. Kana, BG. Gordhan et al. The resuscitation-promoting factors of Mycobacterium tuberculosis are required for virulence and resuscitation from dormancy but are collectively dispensable for growth in vitro. Mol. Microbiol. 2008
Interaction	PhysicalInteraction Rv1009	active	harsharohiratruefriend	2012-10-05
	yeast two hybrid EC. Hett, MC. Chao et al. A partner for the resuscitation-promoting factors of Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	PhysicalInteraction Rv1009	active	harsharohiratruefriend	2012-10-05
	yeast two hybrid KJ. Downing, VV. Mischenko et al. Mutants of Mycobacterium tuberculosis lacking three of the five rpf-like genes are defective for growth in vivo and for resuscitation in vitro. Infect. Immun. 2005
Interaction	PhysicalInteraction Rv1009	active	harsharohiratruefriend	2012-10-05
	yeast two hybrid JM. Tufariello, K. Mi et al. Deletion of the Mycobacterium tuberculosis resuscitation-promoting factor Rv1009 gene results in delayed reactivation from chronic tuberculosis. Infect. Immun. 2006
Interaction	PhysicalInteraction Rv0867c	active	girishgene07	2012-10-05
	Affinity purification (Physical interaction) S. Bardarov, S. Bardarov Jr et al. Specialized transduction: an efficient method for generating marked and unmarked targeted gene disruptions in Mycobacterium tuberculosis, M. bovis BCG and M. smegmatis. Microbiology (Reading, Engl.) 2002
Interaction	PhysicalInteraction Rv0867c	active	girishgene07	2012-10-05
	Affinity purification (Physical interaction) EC. Hett, MC. Chao et al. A mycobacterial enzyme essential for cell division synergizes with resuscitation-promoting factor. PLoS Pathog. 2008
Interaction	PhysicalInteraction Rv0867c	active	girishgene07	2012-10-05
	Affinity purification (Physical interaction) BD. Kana, BG. Gordhan et al. The resuscitation-promoting factors of Mycobacterium tuberculosis are required for virulence and resuscitation from dormancy but are collectively dispensable for growth in vitro. Mol. Microbiol. 2008
Name	Peptidoglycan hydrolase (L,D-peptidase, NLP/P60 family member)	active	mjackson	2012-10-05
	Peptidoglycan turnover
Symbol	ripA	active	mjackson	2012-10-05
	Peptidoglycan turnover