Rv1511 - GDP-D-mannose dehydratase gmdA

Expression: Most Significant Conditions for Rv1511

Protein Domains

Gene Information
Locus	Rv1511
Symbol	gmdA
Gene Name	GDP-D-mannose dehydratase gmdA
Location	1703074 - 1704096 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1023 bp Protein:341 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	36091
Related Genes	MT1561 MT1562 Mvan_4914 Rv1512 SAV730
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1511
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1511 Transcript 1
MKRALITGITGQDGSYLAELLLAKGYEVHGLIRRASTFNTSRIDHLYVDPHQPGARLFLH
YGDLIDGTRLVTLLSTIEPDEVYNLAAQSHVRVSFDEPVHTGDTTGMGSMRLLEAVRLSR
VHCRFYQASSSEMFGASPPPQNELTPFYPRSPYGAAKVYSYWATRNYREAYGLFAVNGIL
FNHESPRRGETFVTRKITRAVARIKAGIQSEVYMGNLDAVRDWGYAPEYVEGMWRMLQTD
EPDDFVLATGRGFTVREFARAAFEHAGLDWQQYVKFDQRYLRPTEVDSLIGDATKAAELL
GWRASVHTDELARIMVDADMAALECEGKPWIDKPMIAGRT*

Genomic Sequence

>Rv1511
GTGAAGCGAGCGCTCATCACCGGAATCACCGGCCAGGACGGCTCGTATCTCGCCGAACTG
CTGCTGGCCAAGGGGTATGAGGTTCACGGGCTCATCCGGCGCGCTTCGACGTTCAACACC
TCGCGGATCGATCACCTCTACGTCGACCCGCACCAACCGGGCGCGCGGCTGTTTCTGCAC
TATGGTGACCTGATCGACGGAACCCGGTTGGTGACCCTGCTGAGCACCATCGAACCCGAC
GAGGTGTACAACCTGGCGGCGCAGTCACACGTGCGGGTGAGCTTCGACGAACCCGTGCAC
ACCGGTGACACCACCGGCATGGGATCCATGCGACTGCTGGAAGCCGTTCGGCTCTCTCGG
GTGCACTGCCGCTTCTATCAGGCGTCCTCGTCGGAGATGTTCGGCGCCTCGCCGCCACCG
CAGAACGAGCTGACGCCGTTCTACCCGCGGTCACCGTATGGCGCCGCCAAGGTCTATTCG
TACTGGGCGACCCGCAATTATCGCGAAGCGTACGGATTGTTCGCCGTTAACGGCATCTTG
TTCAATCACGAATCACCGCGGCGCGGTGAGACGTTCGTGACCCGAAAGATCACCAGGGCC
GTGGCACGCATCAAGGCCGGTATCCAGTCCGAGGTCTATATGGGCAATCTGGATGCGGTC
CGCGACTGGGGGTACGCGCCCGAATACGTCGAAGGCATGTGGCGGATGCTGCAGACCGAC
GAGCCCGACGACTTCGTTTTGGCGACCGGGCGCGGTTTCACCGTGCGTGAGTTCGCGCGG
GCCGCGTTCGAGCATGCCGGTTTGGACTGGCAGCAGTACGTGAAATTCGACCAACGCTAT
CTGCGGCCCACCGAGGTGGATTCGCTGATCGGCGACGCGACCAAGGCTGCCGAATTGCTG
GGCTGGAGGGCTTCGGTGCACACTGACGAGTTGGCTCGGATCATGGTCGACGCGGACATG
GCGGCGCTGGAGTGCGAAGGCAAGCCGTGGATCGACAAGCCGATGATCGCCGGCCGGACA
TGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv1395	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv3286c	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. EP. Williams, JH. Lee et al. Mycobacterium tuberculosis SigF regulates genes encoding cell wall-associated proteins and directly regulates the transcriptional regulatory gene phoY1. J. Bacteriol. 2007