Rv1528c - polyketide synthase associated protein papA4

Expression: Most Significant Conditions for Rv1528c

Protein Domains

Gene Information
Locus	Rv1528c
Symbol	papA4
Gene Name	polyketide synthase associated protein papA4
Location	1728953 - 1729450 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:498 bp Protein:166 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	8988
Related Genes	MT1579
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1528c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1528c Transcript 1
MTQLPQPTWRWWQQRETEQVQSSHIDGEIVGALIPDLAVLHSEDASRAAVGREKHRCSLD
PLGGGFRSRRASMPAGALLLSAVIAIQLDRMNARVFGDGWIGAQACMWVNKFHEESTVTA
LSPSSPIAQGSIARHPETMQSAYVRIAEGGSRDVAPAAQLQRRRP*

Genomic Sequence

>Rv1528c
GTGACTCAGCTTCCACAACCAACCTGGCGCTGGTGGCAGCAAAGAGAGACGGAGCAGGTG
CAGTCCAGCCACATCGACGGAGAAATAGTCGGCGCGTTGATCCCTGACCTGGCGGTGCTG
CACAGCGAGGATGCCTCACGCGCGGCCGTGGGAAGGGAAAAGCATAGATGCTCGTTGGAT
CCTCTAGGTGGCGGCTTCCGTTCCCGTCGTGCCTCGATGCCGGCCGGCGCGCTTCTGCTG
TCTGCGGTCATCGCAATACAACTGGACCGGATGAATGCCAGAGTATTCGGCGATGGCTGG
ATCGGCGCGCAAGCGTGCATGTGGGTCAACAAGTTTCACGAGGAGAGCACCGTCACCGCG
TTGTCCCCCAGTAGTCCGATCGCGCAGGGCTCGATCGCGCGGCATCCAGAGACGATGCAA
TCGGCGTACGTGCGCATCGCCGAGGGCGGATCGCGCGATGTCGCCCCAGCCGCCCAGCTT
CAGCGACGACGGCCTTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv3223c	active	sharanya123	2012-10-05
	Co-expression (Functional linkage) R. Manganelli, MI. Voskuil et al. Role of the extracytoplasmic-function sigma factor sigma(H) in Mycobacterium tuberculosis global gene expression. Mol. Microbiol. 2002
Interaction	Regulatory Rv3223c	active	sharanya123	2012-10-05
	Co-expression (Functional linkage) K. Bhatt, SS. Gurcha et al. Two polyketide-synthase-associated acyltransferases are required for sulfolipid biosynthesis in Mycobacterium tuberculosis. Microbiology (Reading, Engl.) 2007
Interaction	Regulatory Rv3223c	active	sharanya123	2012-10-05
	Co-expression (Functional linkage) G. Etienne, W. Malaga et al. Identification of the polyketide synthase involved in the biosynthesis of the surface-exposed lipooligosaccharides in mycobacteria. J. Bacteriol. 2009
Interaction	RegulatedBy Rv0757	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. SB. Walters, E. Dubnau et al. The Mycobacterium tuberculosis PhoPR two-component system regulates genes essential for virulence and complex lipid biosynthesis. Mol. Microbiol. 2006