Rv1552 - fumarate reductase flavoprotein subunit frdA
Protein Domains

Gene Information
LocusRv1552
SymbolfrdA
Gene Namefumarate reductase flavoprotein subunit frdA
Location1757681 - 1759432 (+)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:1752 bp
Protein:584 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
Search Google Scholar
Orthologs
Orthogroup Number34189
Related GenesMSMEG_1693 MT1603 MT1604 Rv1553
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
Search for regulators of Rv1552
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionTranscription Rv3676activejgalag2012-10-05
Band shift
M. Stapleton, I. Haq et al. Mycobacterium tuberculosis cAMP receptor protein (Rv3676) differs from the Escherichia coli paradigm in its cAMP binding and DNA binding properties and transcription activation properties. J. Biol. Chem. 2010
InteractionTranscription Rv3676activejgalag2012-10-05
Band shift
G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
InteractionPhysicalInteraction Rv1554activevijayachitra2012-10-05
qPCR
AH. Li, WL. Lam et al. Characterization of genes differentially expressed within macrophages by virulent and attenuated Mycobacterium tuberculosis identifies candidate genes involved in intracellular growth. Microbiology (Reading, Engl.) 2008
InteractionPhysicalInteraction Rv1553activeashwinigbhat2012-10-05
qPCR
AH. Li, WL. Lam et al. Characterization of genes differentially expressed within macrophages by virulent and attenuated Mycobacterium tuberculosis identifies candidate genes involved in intracellular growth. Microbiology (Reading, Engl.) 2008
InteractionPhysicalInteraction Rv1555activeashwinigbhat2012-10-05
qPCR
AH. Li, WL. Lam et al. Characterization of genes differentially expressed within macrophages by virulent and attenuated Mycobacterium tuberculosis identifies candidate genes involved in intracellular growth. Microbiology (Reading, Engl.) 2008
InteractionPhysicalInteraction Rv1554activeashwinigbhat2012-10-05
qPCR
AH. Li, WL. Lam et al. Characterization of genes differentially expressed within macrophages by virulent and attenuated Mycobacterium tuberculosis identifies candidate genes involved in intracellular growth. Microbiology (Reading, Engl.) 2008
InteractionPhysicalInteraction Rv1553activeashwinigbhat2012-10-05
qPCR
AH. Li, WL. Lam et al. Characterization of genes differentially expressed within macrophages by virulent and attenuated Mycobacterium tuberculosis identifies candidate genes involved in intracellular growth. Microbiology (Reading, Engl.) 2008
InteractionRegulatory Rv3676activeashwinigbhat2012-10-05
Electrophoretic mobility shift assay (EMSA)
authors,Y. Akhter,S. Yellaboina,A. Farhana,A. Ranjan,N. Ahmed,SE. Hasnain Genome scale portrait of cAMP-receptor protein (CRP) regulons in mycobacteria points to their role in pathogenesis. Gene 2008
InteractionRegulatory Rv3676activeashwinigbhat2012-10-05
Electrophoretic mobility shift assay (EMSA)
Y. Akhter, S. Tundup et al. Novel biochemical properties of a CRP/FNR family transcription factor from Mycobacterium tuberculosis. Int. J. Med. Microbiol. 2007
InteractionRegulatedBy Rv3676activeyamir.moreno2012-10-05
Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support.
G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
TermEC:1.3.99.1 Succinate dehydrogenase. - NRactiveextern:JZUCKER2012-03-06
Traceable author statement to experimental support
authors,KY. Rhee,LP. de Carvalho,R. Bryk,S. Ehrt,J. Marrero,SW. Park,D. Schnappinger,A. Venugopal,C. Nathan Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier. Trends Microbiol. 2011