Rv2126c - PE-PGRS family protein

Expression: Most Significant Conditions for Rv2126c

Protein Domains

Gene Information
Locus	Rv2126c
Symbol	PE_PGRS37
Gene Name	PE-PGRS family protein
Location	2387202 - 2387972 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:771 bp Protein:257 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	26036
Related Genes	MUL_2957
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2126c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2126c Transcript 1
MIGDGANGGPGQPGGPGGLLYGNGGHGGAGAAGQDRGAGNSAGLIGNGGAGGAGGNGGIG
GAGAPGGLGGDGGKGGFADEFTGGFAQGGRGGFGGNGNTGASGGMGGAGGAGGAGGAGGL
LIGDGGAGGAGGIGGAGGVGGGGGAGGTGGGGVASAFGGGNAFGGRGGDGGDGGDGGTGG
AGGARGAGGAGGAGGWLSGHSGAHGAMGSGGEGGAGGGGGARGEAGAGGGTSTGTNPGKA
GAPGTQGDSGDPGPPG*

Genomic Sequence

>Rv2126c
TTGATCGGCGACGGCGCTAACGGCGGGCCGGGCCAGCCCGGTGGGCCGGGTGGATTGCTG
TATGGCAATGGCGGGCACGGTGGGGCGGGTGCCGCCGGTCAGGACCGTGGGGCCGGCAAC
AGTGCGGGATTGATCGGTAACGGCGGGGCCGGCGGCGCCGGTGGCAATGGCGGCATCGGA
GGCGCCGGCGCTCCCGGCGGCCTCGGTGGCGACGGCGGGAAAGGTGGGTTCGCCGACGAA
TTCACTGGGGGCTTTGCCCAAGGTGGCCGCGGTGGCTTCGGCGGCAACGGGAATACCGGA
GCCTCTGGCGGCATGGGTGGTGCCGGCGGCGCGGGCGGGGCTGGCGGGGCCGGCGGGCTG
CTGATCGGTGACGGCGGGGCTGGCGGTGCCGGCGGCATTGGCGGTGCCGGCGGTGTGGGC
GGTGGGGGAGGGGCCGGCGGGACCGGTGGCGGCGGCGTTGCCAGCGCCTTTGGGGGTGGT
AACGCCTTCGGTGGCCGCGGCGGTGACGGCGGCGATGGTGGCGATGGTGGCACCGGCGGC
GCCGGAGGTGCCCGCGGTGCCGGTGGCGCGGGCGGGGCGGGCGGCTGGCTCAGTGGCCAC
TCGGGCGCCCACGGCGCCATGGGCAGCGGCGGCGAGGGCGGGGCCGGCGGCGGCGGCGGT
GCGCGCGGCGAGGCTGGTGCCGGCGGTGGTACGTCGACAGGCACGAATCCCGGCAAAGCC
GGCGCTCCGGGCACTCAGGGTGATTCCGGCGATCCTGGGCCGCCCGGCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Symbol	PE_PGRS38	active	jlew	2012-03-07
	promising new capreomycin target. We employed the data mining to construct an interaction topology of M. tuberculosis genes response to capreomycin. Dampening the virulence factors and respiratory of M. tuberculosis might be the new targets of CPM beyond Rv1364c, pe_pgrs38, pe_pgrs51 which are the salient nodes of the network and represent most promising new capreomycin targets meriting further exploration. authors,F. Zheng,J. Xie The interaction topology of Mycobacterium tuberculosis genes response to capreomycin and novel clues for more drug targets. J. Cell. Biochem. 2011