Rv2196 - ubiquinol-cytochrome C reductase qcrB cytochrome B subunit

Expression: Most Significant Conditions for Rv2196

Protein Domains

Gene Information
Locus	Rv2196
Symbol	qcrB
Gene Name	ubiquinol-cytochrome C reductase qcrB cytochrome B subunit
Location	2459678 - 2461327 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1650 bp Protein:550 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	28883
Related Genes	CE2082 cg2403 DIP1624 jk0722 MAP1935 MAV_2296 Mkms_3356 ML0879 Mmcs_3294 MSMEG_4263 MT2252 MUL_3553 Mvan_3560 nfa17290
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2196
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2196 Transcript 1
MSPKLSPPNIGEVLARQAEDIDTRYHPSAALRRQLNKVFPTHWSFLLGEIALYSFVVLLI
TGVYLTLFFDPSMVDVTYNGVYQPLRGVEMSRAYQSALDISFEVRGGLFVRQIHHWAALM
FAAAIMVHLARIFFTGAFRRPRETNWVIGSLLLILAMFEGYFGYSLPDDLLSGLGLRAAL
SSITLGMPVIGTWLHWALFGGDFPGTILIPRLYALHILLLPGIILALIGLHLALVWFQKH
TQFPGPGRTEHNVVGVRVMPVFAFKSGAFFAAIVGVLGLMGGLLQINPIWNLGPYKPSQV
SAGSQPDFYMMWTEGLARIWPPWEFYFWHHTIPAPVWVAVIMGLVFVLLPAYPFLEKRFT
GDYAHHNLLQRPRDVPVRTAIGAMAIAFYMVLTLAAMNDIIALKFHISLNATTWIGRIGM
VILPPFVYFITYRWCIGLQRSDRSVLEHGVETGIIKRLPHGAYIELHQPLGPVDEHGHPI
PLQYQGAPLPKRMNKLGSAGSPGSGSFLFADSAAEDAALREAGHAAEQRALAALREHQDS
IMGSPDGEH*

Genomic Sequence

>Rv2196
ATGAGTCCGAAACTGAGTCCGCCGAACATTGGTGAGGTCCTGGCCCGCCAAGCCGAAGAC
ATCGACACCCGGTATCACCCCTCGGCGGCGCTGCGTCGTCAGCTCAACAAGGTCTTCCCG
ACCCACTGGTCGTTCTTGCTCGGCGAGATCGCTCTGTACAGCTTCGTGGTCCTGCTGATC
ACCGGCGTGTATTTGACGCTGTTTTTCGATCCGTCCATGGTCGACGTCACCTACAACGGT
GTCTATCAACCGCTGCGGGGCGTCGAGATGTCGCGTGCCTACCAGTCCGCGCTGGACATT
TCCTTCGAGGTGCGCGGTGGCCTGTTCGTGCGCCAGATCCATCACTGGGCCGCTTTGATG
TTCGCGGCGGCAATCATGGTGCACCTGGCACGCATCTTTTTCACCGGAGCGTTCCGGCGG
CCCCGCGAGACCAACTGGGTGATCGGTTCGCTGTTGTTGATCCTGGCGATGTTCGAGGGC
TATTTCGGCTACTCACTGCCTGACGACCTGCTGTCGGGACTCGGTCTGCGCGCGGCACTC
TCGTCGATCACGCTGGGTATGCCGGTAATCGGGACCTGGCTGCACTGGGCGCTGTTTGGC
GGTGACTTCCCCGGCACCATCTTGATCCCCAGGCTCTACGCCCTGCACATTTTACTGTTG
CCGGGGATCATCTTGGCGCTGATCGGGCTGCATCTGGCGTTGGTGTGGTTCCAGAAGCAC
ACCCAGTTCCCCGGCCCGGGCCGCACCGAGCACAACGTCGTCGGCGTGCGGGTGATGCCG
GTGTTCGCGTTCAAGTCCGGCGCATTTTTCGCGGCTATCGTCGGTGTTCTGGGCCTGATG
GGCGGCCTGCTGCAGATCAACCCGATCTGGAATCTGGGGCCCTACAAGCCATCACAGGTG
TCGGCGGGCTCGCAGCCAGACTTCTACATGATGTGGACCGAGGGTCTGGCCCGGATCTGG
CCGCCGTGGGAGTTCTACTTCTGGCATCACACCATTCCCGCCCCGGTCTGGGTCGCCGTG
ATCATGGGCCTGGTTTTCGTCCTGCTACCCGCCTACCCATTCCTGGAGAAGCGGTTTACC
GGCGACTACGCGCATCACAACCTGTTGCAGCGGCCACGGGACGTTCCGGTGCGCACCGCG
ATCGGCGCCATGGCGATCGCCTTCTATATGGTGCTCACTCTCGCGGCGATGAACGACATC
ATCGCGTTGAAGTTCCATATTTCGCTGAATGCAACCACGTGGATTGGCCGCATCGGCATG
GTGATTCTGCCGCCGTTCGTCTACTTCATCACATATCGGTGGTGTATCGGATTGCAGCGC
AGCGATCGGTCGGTGCTCGAGCACGGCGTCGAGACCGGCATCATCAAGCGGCTGCCCCAT
GGCGCCTACATCGAGCTGCATCAGCCCCTCGGCCCGGTCGACGAGCATGGCCACCCGATA
CCGCTTCAGTATCAGGGAGCGCCGCTGCCCAAGCGAATGAACAAGCTGGGCTCGGCCGGA
TCGCCGGGTAGTGGCAGTTTTCTGTTCGCCGACTCCGCGGCAGAGGATGCGGCGCTGCGC
GAGGCAGGGCACGCCGCCGAACAACGTGCCCTTGCCGCACTGCGCGAACACCAGGACAGC
ATCATGGGTTCGCCAGACGGCGAGCACTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	PhysicalInteraction Rv2200c	active	ashwinigbhat	2012-10-05
	Coexpression BD. Kana, EA. Weinstein et al. Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis. J. Bacteriol. 2001
Interaction	PhysicalInteraction Rv2200c	active	priti.priety	2012-10-05
	Coexpression BD. Kana, EA. Weinstein et al. Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis. J. Bacteriol. 2001
Interaction	PhysicalInteraction Rv3043c	active	ashwinigbhat	2012-10-05
	BD. Kana, EA. Weinstein et al. Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis. J. Bacteriol. 2001
Interaction	PhysicalInteraction Rv2200c	active	ashwinigbhat	2012-10-05
	BD. Kana, EA. Weinstein et al. Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis. J. Bacteriol. 2001
Interaction	PhysicalInteraction Rv2193	active	ashwinigbhat	2012-10-05
	BD. Kana, EA. Weinstein et al. Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis. J. Bacteriol. 2001
Interaction	PhysicalInteraction Rv3043c	active	priti.priety	2012-10-05
	BD. Kana, EA. Weinstein et al. Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis. J. Bacteriol. 2001
Interaction	PhysicalInteraction Rv2200c	active	priti.priety	2012-10-05
	BD. Kana, EA. Weinstein et al. Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis. J. Bacteriol. 2001
Interaction	PhysicalInteraction Rv2193	active	priti.priety	2012-10-05
	BD. Kana, EA. Weinstein et al. Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis. J. Bacteriol. 2001
Interaction	Operon Rv2195	active	harsharohiratruefriend	2012-10-05
	Coexpression BD. Kana, EA. Weinstein et al. Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis. J. Bacteriol. 2001
Interaction	Operon Rv2194	active	harsharohiratruefriend	2012-10-05
	Coexpression BD. Kana, EA. Weinstein et al. Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis. J. Bacteriol. 2001
Interaction	Operon Rv2195	active	harsharohiratruefriend	2012-10-05
	Coexpression BD. Kana, EA. Weinstein et al. Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis. J. Bacteriol. 2001
Interaction	Operon Rv2194	active	harsharohiratruefriend	2012-10-05
	Coexpression BD. Kana, EA. Weinstein et al. Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis. J. Bacteriol. 2001
Interaction	PhysicalInteraction Rv2193	active	ashwinigbhat	2012-10-05
	Coexpression BD. Kana, EA. Weinstein et al. Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis. J. Bacteriol. 2001
Interaction	PhysicalInteraction Rv2193	active	priti.priety	2012-10-05
	Coexpression BD. Kana, EA. Weinstein et al. Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis. J. Bacteriol. 2001
Interaction	RegulatedBy Rv1221	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. R. Manganelli, MI. Voskuil et al. The Mycobacterium tuberculosis ECF sigma factor sigmaE: role in global gene expression and survival in macrophages. Mol. Microbiol. 2001