Rv2276 - cytochrome P450 121 cyp121

Expression: Most Significant Conditions for Rv2276

Protein Domains

Gene Information
Locus	Rv2276
Symbol	cyp121
Gene Name	cytochrome P450 121 cyp121
Location	2547749 - 2548939 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1191 bp Protein:397 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	22287
Related Genes	MT2336
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2276
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2276 Transcript 1
MTATVLLEVPFSARGDRIPDAVAELRTREPIRKVRTITGAEAWLVSSYALCTQVLEDRRF
SMKETAAAGAPRLNALTVPPEVVNNMGNIADAGLRKAVMKAITPKAPGLEQFLRDTANSL
LDNLITEGAPADLRNDFADPLATALHCKVLGIPQEDGPKLFRSLSIAFMSSADPIPAAKI
NWDRDIEYMAGILENPNITTGLMGELSRLRKDPAYSHVSDELFATIGVTFFGAGVISTGS
FLTTALISLIQRPQLRNLLHEKPELIPAGVEELLRINLSFADGLPRLATADIQVGDVLVR
KGELVLVLLEGANFDPEHFPNPGSIELDRPNPTSHLAFGRGQHFCPGSALGRRHAQIGIE
ALLKKMPGVDLAVPIDQLVWRTRFQRRIPERLPVLW*

Genomic Sequence

>Rv2276
ATGACCGCGACCGTTCTGCTCGAGGTCCCGTTCTCTGCACGTGGGGATCGGATTCCTGAC
GCCGTCGCAGAATTACGAACCCGCGAGCCTATCCGCAAGGTACGGACCATTACCGGCGCC
GAAGCCTGGCTCGTCTCCTCGTATGCACTGTGCACACAGGTGCTCGAGGATCGGCGTTTT
TCCATGAAGGAAACCGCCGCTGCCGGCGCCCCCCGCCTGAACGCGCTGACTGTTCCACCC
GAAGTGGTCAACAACATGGGAAACATCGCCGACGCGGGACTGCGCAAGGCGGTGATGAAA
GCGATCACACCCAAGGCACCCGGGTTGGAGCAATTCCTACGAGACACCGCGAACTCGCTG
CTGGACAACCTGATTACCGAGGGCGCACCAGCCGATCTGCGCAATGACTTCGCCGACCCG
CTGGCCACTGCCCTGCACTGCAAGGTTCTGGGCATCCCGCAAGAAGACGGCCCGAAGCTG
TTCCGTAGCTTGAGTATCGCTTTCATGAGTTCGGCCGACCCGATCCCCGCCGCGAAGATC
AACTGGGATCGCGACATCGAATACATGGCCGGAATTCTGGAAAACCCAAACATCACGACC
GGCCTCATGGGTGAGCTCAGCCGCCTCCGGAAAGATCCCGCCTACTCGCACGTCTCCGAC
GAACTATTCGCGACCATCGGCGTCACTTTCTTCGGTGCCGGCGTCATCTCAACCGGCAGC
TTCCTCACCACCGCGCTGATATCGCTGATACAACGCCCGCAACTTCGGAACTTGTTGCAC
GAGAAGCCGGAACTGATCCCGGCCGGTGTAGAGGAACTGCTGCGGATCAATCTCTCCTTC
GCCGACGGGTTACCGCGCCTGGCCACCGCCGACATCCAGGTCGGCGACGTGCTGGTCCGC
AAGGGGGAGCTGGTGCTGGTGCTGCTCGAGGGCGCCAACTTCGATCCCGAGCACTTCCCT
AACCCGGGCAGCATCGAACTCGACCGGCCCAACCCCACCTCGCACCTCGCGTTCGGCCGC
GGCCAACACTTCTGTCCTGGATCAGCTCTCGGTCGCCGCCACGCACAGATCGGCATCGAA
GCGCTGTTGAAAAAGATGCCCGGCGTCGACCTGGCTGTGCCCATCGACCAATTGGTCTGG
CGCACCCGATTCCAAAGACGCATCCCCGAACGCCTTCCGGTGCTCTGGTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv1221	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. PA. Fontán, V. Aris et al. Mycobacterium tuberculosis Sigma Factor E Regulon Modulates the Host Inflammatory Response. J. Infect. Dis. 2008