Rv2374c - heat shock protein transcriptional repressor hrcA

Expression: Most Significant Conditions for Rv2374c

Protein Domains

Gene Information
Locus	Rv2374c
Symbol	hrcA
Gene Name	heat shock protein transcriptional repressor hrcA
Location	2654062 - 2655093 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1032 bp Protein:344 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	890
Related Genes	Acel_0783 BL0718 CE2190 cg2516 DIP1721 jk0600 MAP2163c MAV_2022 Mkms_3523 ML0624 Mmcs_3460 MSMEG_4505 MT2443 MUL_3627 Mvan_3837 nfa14250 PPA0915 SAV5569
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2374c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2374c Transcript 1
MGSADERRFEVLRAIVADFVATQEPIGSKSLVERHNLGVSSATVRNDMAVLEAEGYITQP
HTSSGRVPTEKGYREFVDRLEDVKPLSSAERRAIQSFLESGVDLDDVLRRAVRLLAQLTR
QVAVVQYPTLSTSTVRHLEVIALTPARLLMVVITDSGRVDQRIVELGDVIDDHQLAQLRE
ILGQALEGKKLSAASVAVADLASQLGGAGGLGDAVGRAATVLLESLVEHTEERLLLGGTA
NLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETASEQMVGTSMVST
AYGTAHTVYGGMGVVGPTRMDYPGTIASVAAVALYIGDVLGAR*

Genomic Sequence

>Rv2374c
ATGGGAAGCGCCGACGAGCGTCGCTTTGAGGTGCTGCGTGCCATCGTCGCCGACTTCGTT
GCAACCCAGGAACCGATCGGCTCCAAATCCCTGGTGGAACGCCATAACCTGGGAGTCTCG
TCGGCCACAGTCCGCAATGACATGGCGGTGCTGGAAGCCGAAGGCTATATCACTCAGCCA
CACACCAGTTCCGGACGCGTGCCCACGGAGAAGGGCTACCGCGAGTTCGTCGACCGGCTC
GAGGACGTCAAACCCCTATCGTCGGCCGAGCGCCGGGCGATCCAGAGCTTCCTTGAATCC
GGTGTCGATCTCGACGACGTGCTGCGCCGTGCCGTGCGATTGCTGGCGCAGCTGACCCGC
CAGGTGGCCGTCGTGCAGTACCCGACGTTGTCAACGTCGACCGTTCGCCACTTGGAGGTG
ATCGCGCTGACACCGGCCCGGCTGCTGATGGTGGTCATCACCGACTCCGGCCGGGTTGAT
CAGCGCATCGTCGAACTCGGCGATGTCATCGACGATCACCAGCTAGCCCAGCTGCGTGAA
ATACTCGGCCAGGCGCTGGAAGGCAAGAAGCTTTCAGCGGCTTCGGTGGCGGTCGCCGAC
CTCGCCAGCCAGCTGGGCGGCGCCGGCGGATTGGGCGACGCCGTGGGCCGCGCGGCGACC
GTATTGCTGGAGTCGCTAGTGGAGCACACCGAGGAACGCCTTTTGCTGGGCGGTACCGCC
AACCTAACCCGCAACGCTGCGGACTTCGGTGGTTCACTGCGGTCAATATTGGAAGCACTT
GAGGAGCAGGTGGTGGTGTTGCGGCTGCTGGCGGCTCAGCAGGAAGCCGGCAAGGTGACG
GTTCGCATAGGTCATGAGACGGCGTCTGAGCAGATGGTGGGCACCTCGATGGTGTCGACG
GCCTACGGTACCGCCCATACCGTCTACGGCGGTATGGGTGTGGTGGGCCCCACCCGGATG
GACTATCCGGGAACTATCGCCAGCGTGGCTGCGGTTGCTCTTTATATCGGCGACGTCCTG
GGTGCTCGATGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv0353	active	chirupolo	2012-10-05
	Co Expression (Functional linkage) GR. Stewart, L. Wernisch et al. Dissection of the heat-shock response in Mycobacterium tuberculosis using mutants and microarrays. Microbiology (Reading, Engl.) 2002
Interaction	Regulates Rv3418c	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	Regulates Rv0991c	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	Regulates Rv0440	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	Regulates Rv0439c	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008