Rv2502c - acetyl-/propionyl-CoA carboxylase beta subunit accD1

Expression: Most Significant Conditions for Rv2502c

Protein Domains

Gene Information
Locus	Rv2502c
Symbol	accD1
Gene Name	acetyl-/propionyl-CoA carboxylase beta subunit accD1
Location	2816885 - 2818474 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1590 bp Protein:530 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	25739
Related Genes	jk1551 MAP2314c MAV_1670 Mkms_3704 Mmcs_3631 MSMEG_4717 MT2577 Mvan_4091 nfa50370 SAV5278
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2502c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2502c Transcript 1
MTTPSIAIAPSFADEHRRLVAELNNKLAAAALGGNERARKRHVSRGKLLPRERVDRLLDP
GSPFLELAPLAAGGMYGDESPGAGIITGIGRVSGRQCVIVANDATVKGGTYYPMTVKKHL
RAQEVALQNMLPCIYLVDSGGAFLPRQDEVFPDREHFGRIFYNQATMSAKGIPQVAAVLG
SCTAGGAYVPAMSDEAVIVREQGTIFLGGPPLVKAATGEIVSAEELGGGDLHSRTSGVTD
HLADDDEDALRIVRAIADTFGPCEPAQWDVRRSVEPKYPQAELYDVVPPDPRVPYDVHEV
VVRIVDGSEFSEFKAKYGKTLVTAFARVHGHPVGIVANNGVLFSESALKGAHFIELCDKR
KIPLLFLQNIAGFMVGRDYEAGGIAKHGAKMVTAVACARVPKLTVVIGGSYGAGNYSMCG
RAYSPRFLWMWPNARISVMGGEQAASVLATVRGEQLSAAGTPWSPDEEEAFKAPIRAQYE
DQGNPYYSTARLWDDGIIDPADTRTVVGLALSLCAHAPLDQVGYGVFRM*

Genomic Sequence

>Rv2502c
GTGACCACCCCGTCGATAGCAATAGCCCCCTCGTTCGCCGACGAGCACCGCCGGCTGGTG
GCGGAATTGAACAATAAGCTCGCCGCCGCCGCCCTGGGCGGCAACGAACGCGCCCGGAAA
CGCCACGTCAGCCGCGGCAAGCTGTTGCCCCGCGAACGGGTGGACCGCCTGCTCGACCCG
GGCAGCCCTTTCCTCGAGCTGGCTCCGCTGGCCGCTGGCGGCATGTACGGCGACGAATCC
CCGGGCGCGGGAATCATCACCGGGATCGGCCGGGTATCCGGACGCCAGTGCGTGATCGTC
GCCAACGACGCGACGGTCAAGGGCGGTACCTACTACCCGATGACGGTCAAGAAGCACCTG
CGCGCCCAGGAGGTCGCGCTGCAGAATATGCTGCCGTGCATCTATCTGGTCGACTCCGGC
GGCGCCTTCCTGCCCCGCCAAGACGAGGTGTTTCCCGACCGCGAGCATTTCGGGCGGATC
TTCTACAACCAGGCGACGATGAGCGCCAAGGGCATTCCGCAGGTGGCGGCGGTTCTCGGC
TCCTGCACGGCGGGTGGCGCTTATGTGCCGGCGATGAGTGACGAGGCCGTCATCGTCCGT
GAGCAGGGCACGATCTTCCTCGGCGGTCCGCCACTGGTGAAGGCGGCCACCGGCGAGATC
GTCTCGGCCGAGGAACTTGGCGGTGGCGACTTGCACTCGCGCACGTCCGGTGTCACCGAC
CATCTGGCTGACGACGACGAGGACGCGCTGCGGATCGTGCGCGCGATCGCGGACACCTTC
GGCCCGTGCGAACCCGCCCAATGGGATGTGCGCCGTTCGGTCGAGCCCAAGTACCCGCAG
GCCGAGCTCTACGATGTGGTGCCCCCGGATCCCCGGGTCCCTTACGACGTTCATGAGGTC
GTCGTGCGGATTGTTGACGGCAGCGAATTCAGCGAGTTCAAGGCTAAATACGGCAAGACT
CTGGTGACTGCGTTTGCACGCGTCCACGGCCACCCGGTCGGGATCGTCGCCAACAACGGC
GTGTTGTTCAGCGAATCCGCGCTCAAGGGAGCGCATTTCATCGAGCTGTGCGACAAACGC
AAGATTCCGCTGCTGTTCCTGCAGAACATCGCCGGCTTCATGGTCGGCCGCGACTACGAG
GCCGGCGGAATCGCCAAGCATGGCGCCAAGATGGTCACCGCGGTGGCCTGCGCGCGGGTG
CCCAAGTTGACCGTGGTGATCGGCGGATCCTATGGTGCGGGTAACTATTCGATGTGCGGA
CGCGCGTACTCGCCCCGGTTCCTGTGGATGTGGCCGAACGCGCGGATCTCGGTGATGGGC
GGTGAGCAGGCCGCGTCCGTGTTGGCGACCGTGCGCGGCGAGCAGCTGTCCGCGGCCGGC
ACACCCTGGTCACCCGACGAGGAGGAAGCGTTCAAGGCGCCCATCCGAGCGCAGTACGAA
GACCAGGGTAACCCCTACTATTCAACTGCCCGGCTGTGGGATGACGGTATCATAGACCCT
GCGGACACCAGAACGGTTGTTGGGCTTGCCCTTTCGTTGTGTGCCCACGCTCCGCTGGAT
CAGGTTGGCTACGGCGTCTTCCGGATGTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Name	Probable acetyl-/propionyl-CoA carboxylase (beta subunit), annotated in TB database to be involved in mycocerosate biosynthesis	active	mjackson	2012-10-05
	Claisen-type condensation
Term	EC:6.4.1.4 Methylcrotonoyl-CoA carboxylase. - NR	active	extern:JZUCKER	2012-03-06
	Traceable author statement to experimental support authors,KY. Rhee,LP. de Carvalho,R. Bryk,S. Ehrt,J. Marrero,SW. Park,D. Schnappinger,A. Venugopal,C. Nathan Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier. Trends Microbiol. 2011