Rv2558 - conserved hypothetical protein

Expression: Most Significant Conditions for Rv2558

Protein Domains

Gene Information
Locus	Rv2558
Symbol
Gene Name	conserved hypothetical protein
Location	2877831 - 2878541 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:711 bp Protein:237 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	4060
Related Genes	MAP1074c MAP1075c MAV_3433 Mkms_2391 Mmcs_2344 MT2634 MT2635 MUL_1752 Mvan_4767 Rv2557
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2558
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2558 Transcript 1
MPGSAGWRKVFGGTGGATGALPRHGRGSIVYARSTTIEAQPLSVDIGIAHVRDVVMPALQ
EIDGCVGVSLLVDRQSGRCIATSAWETLEAMRASVERVAPIRDRAALMFAGSARVEEWDI
ALLHRDHPSHEGACVRATWLKVVPDQLGRSLEFYRTSVLPELESLDGFCSASLMVDHPAC
RRAVSCSTFDSMDAMARNRDRASELRSRRVRELGAEVLDVAEFELAIAHLRVPELV*

Genomic Sequence

>Rv2558
TTGCCAGGCTCAGCCGGTTGGAGGAAGGTATTTGGTGGGACCGGTGGCGCCACCGGGGCG
CTGCCCCGACACGGGAGGGGGTCGATCGTGTACGCACGCTCAACCACCATTGAGGCGCAA
CCTCTGTCGGTCGACATTGGAATCGCGCATGTTCGTGACGTCGTCATGCCCGCTTTGCAG
GAGATCGACGGGTGTGTCGGGGTGTCGCTGTTGGTCGACCGGCAATCCGGCCGGTGCATC
GCCACCAGCGCCTGGGAGACCTTGGAGGCGATGCGCGCCAGCGTCGAGCGGGTGGCACCC
ATCCGCGACCGCGCCGCGCTGATGTTCGCCGGTAGTGCCCGGGTCGAGGAATGGGACATC
GCCCTGTTGCACCGCGACCACCCGTCGCATGAGGGGGCATGCGTGCGCGCCACCTGGCTC
AAAGTGGTGCCAGACCAGCTCGGTCGGTCCCTGGAGTTCTACCGCACGTCCGTACTTCCC
GAGCTGGAGAGTCTGGACGGGTTCTGCAGCGCCAGCCTGATGGTCGACCACCCCGCTTGC
CGGCGTGCGGTGTCGTGCTCGACGTTCGACAGCATGGACGCGATGGCCCGCAACCGCGAC
CGGGCGAGCGAGCTGCGCAGCAGGCGCGTCCGGGAATTGGGAGCCGAGGTCCTCGACGTC
GCCGAATTCGAACTGGCGATCGCACATCTACGGGTACCCGAGCTGGTCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv2557	active	gaurisd10	2012-10-05
	Structural Analysis A. Luthra, SS. Malik et al. Cloning, purification and comparative structural analysis of two hypothetical proteins from Mycobacterium tuberculosis found in the human granuloma during persistence and highly up-regulated under carbon-starvation conditions. Protein Expr. Purif. 2008
Interaction	Regulatory Rv2557	active	gaurisd10	2012-10-05
	Structural Analysis G. Fenhalls, L. Stevens et al. In situ detection of Mycobacterium tuberculosis transcripts in human lung granulomas reveals differential gene expression in necrotic lesions. Infect. Immun. 2002
Interaction	Regulatory Rv2557	active	gaurisd10	2012-10-05
	Structural Analysis BG. Gordhan, DA. Smith et al. The carbon starvation-inducible genes Rv2557 and Rv2558 of Mycobacterium tuberculosis are not required for long-term survival under carbon starvation and for virulence in SCID mice. Tuberculosis (Edinburgh, Scotland) 2006
Interaction	Regulatory Rv2557	active	gaurisd10	2012-10-05
	Spectrophotometric A. Luthra, SS. Malik et al. Cloning, purification and comparative structural analysis of two hypothetical proteins from Mycobacterium tuberculosis found in the human granuloma during persistence and highly up-regulated under carbon-starvation conditions. Protein Expr. Purif. 2008
Interaction	Regulatory Rv2557	active	gaurisd10	2012-10-05
	Spectrophotometric G. Fenhalls, L. Stevens et al. In situ detection of Mycobacterium tuberculosis transcripts in human lung granulomas reveals differential gene expression in necrotic lesions. Infect. Immun. 2002
Interaction	Regulatory Rv2557	active	gaurisd10	2012-10-05
	Spectrophotometric BG. Gordhan, DA. Smith et al. The carbon starvation-inducible genes Rv2557 and Rv2558 of Mycobacterium tuberculosis are not required for long-term survival under carbon starvation and for virulence in SCID mice. Tuberculosis (Edinburgh, Scotland) 2006
Interaction	Regulatory Rv2557	active	gaurisd10	2012-10-05
	Structural Analysis A. Luthra, SS. Malik et al. Cloning, purification and comparative structural analysis of two hypothetical proteins from Mycobacterium tuberculosis found in the human granuloma during persistence and highly up-regulated under carbon-starvation conditions. Protein Expr. Purif. 2008
Interaction	Regulatory Rv2557	active	gaurisd10	2012-10-05
	Structural Analysis G. Fenhalls, L. Stevens et al. In situ detection of Mycobacterium tuberculosis transcripts in human lung granulomas reveals differential gene expression in necrotic lesions. Infect. Immun. 2002
Interaction	Regulatory Rv2557	active	gaurisd10	2012-10-05
	Structural Analysis BG. Gordhan, DA. Smith et al. The carbon starvation-inducible genes Rv2557 and Rv2558 of Mycobacterium tuberculosis are not required for long-term survival under carbon starvation and for virulence in SCID mice. Tuberculosis (Edinburgh, Scotland) 2006
Interaction	Regulatory Rv2557	active	gaurisd10	2012-10-05
	Spectrophotometric A. Luthra, SS. Malik et al. Cloning, purification and comparative structural analysis of two hypothetical proteins from Mycobacterium tuberculosis found in the human granuloma during persistence and highly up-regulated under carbon-starvation conditions. Protein Expr. Purif. 2008
Interaction	Regulatory Rv2557	active	gaurisd10	2012-10-05
	Spectrophotometric G. Fenhalls, L. Stevens et al. In situ detection of Mycobacterium tuberculosis transcripts in human lung granulomas reveals differential gene expression in necrotic lesions. Infect. Immun. 2002
Interaction	Regulatory Rv2557	active	gaurisd10	2012-10-05
	Spectrophotometric BG. Gordhan, DA. Smith et al. The carbon starvation-inducible genes Rv2557 and Rv2558 of Mycobacterium tuberculosis are not required for long-term survival under carbon starvation and for virulence in SCID mice. Tuberculosis (Edinburgh, Scotland) 2006