Rv2623 - conserved hypothetical protein
Protein Domains

Gene Information
LocusRv2623
SymbolTB31.7
Gene Nameconserved hypothetical protein
Location2949593 - 2950486 (+)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:894 bp
Protein:298 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number35089
Related Genescg1595 MAP3179c MAV_4010 Mkms_4202 Mkms_5069 Mmcs_4127 Mmcs_4981 MSMEG_5245 MT2698 MT3220 MUL_2424 MUL_3267 Mvan_2549 Rv3134c
Transcriptional Regulation
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Regulatory Network
Search for regulators of Rv2623
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionTranscription Rv3133cactivesourish102012-10-05
Co-expression (Functional linkage)
MA. Florczyk, LA. McCue et al. A family of acr-coregulated Mycobacterium tuberculosis genes shares a common DNA motif and requires Rv3133c (dosR or devR) for expression. Infect. Immun. 2003
InteractionTranscription Rv3133cactivesourish102012-10-05
Co-expression (Functional linkage)
authors,M. Seki,I. Honda,I. Fujita,I. Yano,S. Yamamoto,A. Koyama Whole genome sequence analysis of Mycobacterium bovis bacillus Calmette-Guérin (BCG) Tokyo 172: a comparative study of BCG vaccine substrains. Vaccine 2009
InteractionTranscription Rv3133cactivesourish102012-10-05
Co-expression (Functional linkage)
JE. Drumm, K. Mi et al. Mycobacterium tuberculosis universal stress protein Rv2623 regulates bacillary growth by ATP-Binding: requirement for establishing chronic persistent infection. PLoS Pathog. 2009
InteractionRegulatedBy Rv0348activeyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
B. Abomoelak, EA. Hoye et al. mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2009
InteractionRegulatedBy Rv0981activeyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
H. He, R. Hovey et al. MprAB is a stress-responsive two-component system that directly regulates expression of sigma factors SigB and SigE in Mycobacterium tuberculosis. J. Bacteriol. 2006
InteractionRegulatedBy Rv3133cactiveyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
HD. Park, KM. Guinn et al. Rv3133c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis. Mol. Microbiol. 2003