Rv2687c - antibiotic-transport membrane leucine and valine rich protein ABC transporter

Expression: Most Significant Conditions for Rv2687c

Protein Domains

Gene Information
Locus	Rv2687c
Symbol
Gene Name	antibiotic-transport membrane leucine and valine rich protein ABC transporter
Location	3004035 - 3004748 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:714 bp Protein:238 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	6523
Related Genes	Mkms_2249 Mmcs_2203 MSMEG_1503 MT2761 MUL_3325 Mvan_0775
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2687c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2687c Transcript 1
MTRLVPALRLELTLQVRQKFLHAAVFSGLIWLAVLLPMPVSLRPVAEPYVLVGDIAIIGF
FFVGGTVFFEKQERTIGAIVSTPLRFWEYLAAKLTVLLAISLFVAVVVATIVHGLGYHLL
PLVAGIVLGTLLMLLVGFSSSLPFASVTDWFLAAVIPLAIMLAPPVVHYSGLWPNPVLYL
IPTQGPLLLLGAAFDQVSLAPWQVGYAVVYPIVCAAGLCRAAKALFGRYVVQRSGVL*

Genomic Sequence

>Rv2687c
ATGACCCGGTTGGTGCCTGCGCTGCGGCTCGAGCTGACGCTACAGGTGCGGCAGAAGTTC
TTGCATGCCGCCGTTTTCTCCGGACTGATTTGGCTGGCAGTGCTGCTGCCGATGCCGGTC
AGCCTGCGCCCGGTCGCCGAACCCTATGTCCTGGTGGGTGATATCGCGATCATCGGGTTC
TTCTTCGTCGGCGGGACCGTGTTCTTCGAGAAGCAGGAGCGCACGATCGGCGCGATCGTC
TCGACGCCGCTGCGGTTCTGGGAGTACCTGGCTGCCAAACTAACTGTGCTGCTGGCGATC
TCGCTGTTCGTTGCGGTTGTCGTGGCCACCATCGTTCACGGGCTTGGTTACCACCTGCTG
CCGCTGGTGGCCGGCATCGTGCTGGGCACACTGCTGATGCTGCTGGTCGGCTTCAGTTCC
TCGTTGCCGTTCGCCTCGGTGACCGATTGGTTCCTGGCGGCGGTCATCCCGCTCGCGATC
ATGCTGGCGCCGCCGGTGGTGCACTACTCCGGCCTGTGGCCCAACCCGGTGCTTTACCTC
ATCCCCACCCAGGGGCCGCTGCTCTTGCTCGGCGCGGCGTTCGATCAGGTGAGCTTGGCG
CCCTGGCAGGTCGGGTATGCGGTGGTCTACCCAATCGTGTGTGCGGCGGGATTGTGCCGG
GCGGCCAAGGCGCTATTCGGCCGTTATGTCGTGCAAAGATCGGGTGTGCTGTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	PhysicalInteraction Rv2688c	active	shahanup86	2012-10-05
	Operon (Functional linkage) MR. Pasca, P. Guglierame et al. Rv2686c-Rv2687c-Rv2688c, an ABC fluoroquinolone efflux pump in Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 2004
Interaction	PhysicalInteraction Rv2688c	active	shahanup86	2012-10-05
	Operon (Functional linkage) MR. Pasca, P. Guglierame et al. Rv2686c-Rv2687c-Rv2688c, an ABC fluoroquinolone efflux pump in Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 2004
Interaction	PhysicalInteraction Rv2686c	active	shahanup86	2012-10-05
	Operon (Functional linkage) MR. Pasca, P. Guglierame et al. Rv2686c-Rv2687c-Rv2688c, an ABC fluoroquinolone efflux pump in Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 2004
Interaction	PhysicalInteraction Rv2686c	active	anshula.arora1990	2012-10-05
	operon(functional linkage) MR. Pasca, P. Guglierame et al. Rv2686c-Rv2687c-Rv2688c, an ABC fluoroquinolone efflux pump in Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 2004
Interaction	Regulatory Rv0616c	active	akankshajain.21	2012-10-05
	Co-expression (Functional linkage) T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003
Interaction	RegulatedBy Rv0491	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003