Rv3050c - transcriptional regulator, asnC-family

Expression: Most Significant Conditions for Rv3050c

Protein Domains

Gene Information
Locus	Rv3050c
Symbol
Gene Name	transcriptional regulator, asnC-family
Location	3411217 - 3411957 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:741 bp Protein:247 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	20872
Related Genes	MAP3099c MAP3105 MAV_3917 MAV_3923 Mkms_1860 Mkms_1871 Mkms_1874 ML1733 Mmcs_1813 Mmcs_1824 Mmcs_1827 MSMEG_1015 MSMEG_1029 MSMEG_2295 MSMEG_2309 MT3136 MT3141 MUL_1879 MUL_3399 Mvan_2038 Mvan_2056 nfa43110 Rv3055
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3050c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3050c Transcript 1
MVRIPRPHPSAKPGVKVDARSERWREHRKKVRNEIVDAAFRAIDRLGPELSVRQIAEEAG
TAKPKIYRHFTDKSDLLEAIGMRLRDMLWAAIFPSLDLATDSAREVIRRSVEEYVNLVDQ
HPNVLRVFIQGRSAKQSEATVRTLNEGREITLAMAEMFNNELREMELNRAALELAAFAAF
GSAASATEWWLGPEPDSPRRMPREQFVAHLTTIMMGVIVGTAEALGIAVDPDQPIHDAVP
NNPAVR*

Genomic Sequence

>Rv3050c
GTGGTCAGAATCCCCCGACCCCACCCCAGTGCAAAGCCGGGGGTGAAAGTCGACGCCCGC
AGTGAACGGTGGCGTGAGCACCGCAAGAAGGTGCGCAACGAAATCGTCGACGCGGCGTTC
CGCGCTATCGACCGGCTGGGCCCCGAGCTGAGTGTGCGCCAAATCGCCGAAGAGGCCGGC
ACCGCCAAGCCCAAGATCTATCGGCATTTCACCGACAAGTCCGATTTGCTCGAGGCTATC
GGGATGCGACTGCGTGACATGCTGTGGGCGGCGATCTTCCCGTCGCTCGACTTAGCCACC
GACTCTGCCCGCGAAGTTATCCGGCGCAGCGTCGAGGAGTACGTCAACCTCGTCGACCAG
CACCCCAACGTGCTGCGGGTGTTCATTCAGGGCCGCTCGGCAAAGCAGTCCGAGGCGACG
GTACGCACCCTCAACGAAGGCCGGGAGATCACGCTGGCCATGGCCGAGATGTTCAACAAC
GAGCTGCGCGAGATGGAGCTGAATCGAGCCGCGCTCGAACTCGCCGCATTCGCGGCGTTC
GGATCGGCCGCATCGGCAACCGAGTGGTGGTTGGGCCCCGAACCCGACAGCCCGCGCCGC
ATGCCGCGTGAGCAGTTCGTGGCGCATCTGACCACCATCATGATGGGCGTGATCGTCGGC
ACCGCCGAAGCGCTGGGCATCGCGGTCGACCCTGACCAACCGATCCACGACGCGGTACCC
AACAATCCCGCCGTGCGTTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Transcription Rv3676	active	jgalag	2012-10-05
	Band shift M. Stapleton, I. Haq et al. Mycobacterium tuberculosis cAMP receptor protein (Rv3676) differs from the Escherichia coli paradigm in its cAMP binding and DNA binding properties and transcription activation properties. J. Biol. Chem. 2010
Interaction	Transcription Rv3676	active	jgalag	2012-10-05
	Band shift G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	RegulatedBy Rv1221	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. PA. Fontán, V. Aris et al. Mycobacterium tuberculosis Sigma Factor E Regulon Modulates the Host Inflammatory Response. J. Infect. Dis. 2008
Interaction	RegulatedBy Rv3676	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008