Rv3084 - acetyl-hydrolase/esterase lipR

Expression: Most Significant Conditions for Rv3084

Protein Domains

Gene Information
Locus	Rv3084
Symbol	lipR
Gene Name	acetyl-hydrolase/esterase lipR
Location	3449997 - 3450923 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:927 bp Protein:309 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	34831
Related Genes	BL0582 cg1320 MT3169 MT3181 Mvan_1822 Rv3097c
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3084
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3084 Transcript 1
MNLRKNVIRSVLRGARPLFASRRLGIAGRRVLLATLTAGARAPKGTRFQRVSIAGVPVQR
VQPPHAATSGTLIYLHGGAYALGSARGYRGLAAQLAAAAGMTALVPDYTRAPHAHYPVAL
EEMAAVYTRLLDDGLDPKTTVIAGDSAGGGLTLALAMALRDRGIQAPAALGLICPWADLA
VDIEATRPALRDPLILPSMCTEWAPRYVGSSDPRLPGISPVYGDMSGLPPIVMQTAGDDP
ICVDADKIETACAASKTSIEHRRFAGMWHDFHLQVSLLPEARDAIADLGARLRGHLHQSQ
GQPRGVVK*

Genomic Sequence

>Rv3084
ATGAACCTGCGCAAAAACGTCATCCGGTCCGTATTACGTGGTGCCCGGCCACTGTTCGCT
TCCCGCCGGCTGGGTATTGCCGGCCGTCGAGTCCTGCTGGCGACGCTGACGGCCGGCGCG
CGCGCCCCCAAGGGCACCCGCTTTCAGCGCGTCAGCATCGCCGGTGTCCCGGTCCAGCGG
GTGCAACCCCCCCATGCGGCAACCAGCGGGACGCTGATCTACCTGCACGGCGGTGCCTAC
GCCCTGGGCAGCGCCCGGGGCTACCGCGGCCTGGCCGCCCAGCTCGCGGCGGCGGCCGGA
ATGACGGCGCTGGTCCCCGACTACACCCGCGCACCGCACGCCCACTATCCAGTGGCCCTC
GAAGAGATGGCTGCGGTGTACACCCGCTTGCTCGACGACGGGCTCGACCCGAAAACGACC
GTCATCGCCGGTGATTCGGCTGGCGGAGGGTTGACCCTGGCGCTGGCCATGGCGCTGCGC
GATCGCGGCATCCAGGCCCCGGCCGCACTCGGCCTGATCTGCCCGTGGGCCGATCTCGCC
GTCGACATCGAAGCGACGCGACCGGCGCTGCGCGATCCGCTCATTCTTCCGTCGATGTGC
ACCGAATGGGCGCCGCGCTACGTAGGGTCCTCCGATCCGCGGCTGCCCGGTATCTCCCCG
GTCTACGGCGACATGAGCGGCCTGCCGCCCATCGTCATGCAGACCGCGGGCGACGATCCG
ATCTGCGTTGACGCGGACAAGATCGAAACCGCCTGCGCCGCTTCGAAAACAAGCATCGAG
CATCGCCGGTTCGCGGGCATGTGGCACGACTTCCATCTGCAGGTCAGTCTGCTCCCCGAA
GCCCGCGACGCGATCGCCGACCTCGGGGCAAGGCTGCGCGGCCACCTCCACCAATCGCAG
GGACAACCACGGGGAGTAGTCAAATGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Transcription Rv3088	active	sourish10	2012-10-05
	Operon (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3085	active	sourish10	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Activation Rv3080c	active	sourish10	2012-10-05
	Structural Analysis P. Kumar, D. Kumar et al. The Mycobacterium tuberculosis protein kinase K modulates activation of transcription from the promoter of mycobacterial monooxygenase operon through phosphorylation of the transcriptional regulator VirS. J. Biol. Chem. 2009
Interaction	Activation Rv3080c	active	sourish10	2012-10-05
	Spectrophotometric P. Kumar, D. Kumar et al. The Mycobacterium tuberculosis protein kinase K modulates activation of transcription from the promoter of mycobacterial monooxygenase operon through phosphorylation of the transcriptional regulator VirS. J. Biol. Chem. 2009
Interaction	Transcription Rv3082c	active	sourish10	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3089	active	sourish10	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3088	active	sourish10	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3087	active	sourish10	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3086	active	sourish10	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3085	active	sourish10	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3083	active	sourish10	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3083	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3082c	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3082c	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) P. Kumar, D. Kumar et al. The Mycobacterium tuberculosis protein kinase K modulates activation of transcription from the promoter of mycobacterial monooxygenase operon through phosphorylation of the transcriptional regulator VirS. J. Biol. Chem. 2009
Interaction	Transcription Rv3082c	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) A. Singh, R. Gupta et al. Requirement of the mymA operon for appropriate cell wall ultrastructure and persistence of Mycobacterium tuberculosis in the spleens of guinea pigs. J. Bacteriol. 2005
Interaction	Activation Rv3080c	active	priyadarshinipriyanka2001	2012-10-05
	Affinity purification (Physical interaction) P. Kumar, D. Kumar et al. The Mycobacterium tuberculosis protein kinase K modulates activation of transcription from the promoter of mycobacterial monooxygenase operon through phosphorylation of the transcriptional regulator VirS. J. Biol. Chem. 2009
Interaction	RegulatedBy Rv3082c	active	yamir.moreno	2012-10-05
	LacZ-promoter fusion. expression levels of LacZ- regulated promoter fusion measured and compared between wild-type and trans-element mutation (knockout, over expression etc.). Gfp-promoter fusion. expression levels of gfp-regulated promoter fusion measured and compared between wild-type and trans-element mutation (knockout, over expression etc.). A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	RegulatedBy Rv3082c	active	yamir.moreno	2012-10-05
	LacZ-promoter fusion. expression levels of LacZ- regulated promoter fusion measured and compared between wild-type and trans-element mutation (knockout, over expression etc.). Gfp-promoter fusion. expression levels of gfp-regulated promoter fusion measured and compared between wild-type and trans-element mutation (knockout, over expression etc.). A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003