Rv3328c - alternative RNA polymerase sigma factor sigJ

Expression: Most Significant Conditions for Rv3328c

Protein Domains

Gene Information
Locus	Rv3328c
Symbol	sigJ
Gene Name	alternative RNA polymerase sigma factor sigJ
Location	3713394 - 3714332 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:939 bp Protein:313 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	27403
Related Genes	MAP3446c MAV_4301 Mkms_1240 Mmcs_1223 MSMEG_1666 MT3411 MT3431 MUL_2678 Mvan_1575 Rv3312c
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3328c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3328c Transcript 1
MEVSEFEALRQHLMSVAYRLTGTVADAEDIVQEAWLRWDSPDTVIADPRAWLTTVVSRLG
LDKLRSAAHRRETYTGTWLPEPVVTGLDATDPLAAVVAAEDARFAAMVVLERLRPDQRVA
FVLHDGFAVPFAEVAEVLGTSEAAARQLASRARKAVTAQPALISGDPDPAHNEVVGRLMA
AMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKVVRFILGLVQRYGPGLFGAN
QLALVNGELGAYTAGLPGVDGYRAMAPRITAITVRDGKVCALWDIANPDKFTGSPLKERR
AQPTGRGRHHRN*

Genomic Sequence

>Rv3328c
ATGGAGGTTTCCGAATTCGAGGCACTGCGACAGCATCTCATGTCGGTCGCCTACAGGCTG
ACCGGCACGGTCGCCGATGCTGAGGACATCGTGCAGGAGGCCTGGCTGCGCTGGGACTCA
CCGGACACCGTGATCGCCGACCCGCGGGCCTGGCTGACCACCGTGGTGAGCCGGCTGGGT
CTGGACAAGTTGAGGTCGGCGGCGCACCGGCGGGAGACCTACACCGGCACCTGGCTGCCC
GAACCGGTGGTCACCGGCTTGGACGCGACCGATCCGTTGGCCGCCGTGGTGGCCGCCGAG
GACGCCAGGTTCGCGGCCATGGTGGTGCTGGAGCGGCTGCGCCCCGATCAGCGGGTCGCG
TTCGTGCTGCACGACGGGTTCGCCGTGCCGTTTGCCGAAGTGGCCGAGGTGCTGGGAACC
AGCGAGGCCGCCGCGCGCCAGCTGGCGTCGCGGGCCCGCAAGGCCGTCACGGCGCAGCCC
GCCCTGATATCGGGGGATCCGGATCCGGCCCACAACGAGGTGGTCGGCCGGCTGATGGCC
GCCATGGCCGCTGGTGACCTGGACACGGTGGTGTCGCTGCTGCATCCCGACGTGACGTTT
ACCGGCGATTCGAATGGCAAGGCGCCCACAGCGGTACGGGCCGTCCGCGGATCCGACAAG
GTGGTCCGGTTCATACTCGGGCTGGTCCAGCGTTACGGCCCGGGGCTCTTCGGCGCGAAT
CAGCTGGCGCTGGTCAACGGAGAGCTCGGCGCCTACACGGCGGGCTTACCCGGGGTCGAC
GGGTATCGGGCGATGGCGCCGCGGATCACCGCGATAACCGTGCGCGACGGAAAGGTGTGC
GCGCTGTGGGATATCGCCAATCCCGACAAGTTCACCGGCTCTCCGCTGAAGGAACGTCGG
GCGCAGCCCACGGGACGCGGCAGGCATCACCGGAATTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv1189	active	dreamsbeyondinfinity	2012-10-05
	Co-expression (Functional linkage) R. Manganelli,E. Dubnau,S. Tyagi,FR. Kramer,I. Smith Differential expression of 10 sigma factor genes in Mycobacterium tuberculosis. Mol. Microbiol. 1999
Interaction	Regulatory Rv1189	active	dreamsbeyondinfinity	2012-10-05
	Co-expression (Functional linkage) A. Waagmeester, J. Thompson et al. Identifying sigma factors in Mycobacterium smegmatis by comparative genomic analysis. Trends Microbiol. 2005
Interaction	Regulatory Rv1189	active	dreamsbeyondinfinity	2012-10-05
	Co-expression (Functional linkage) J. Pendzich, W. Maksymowicz-Mazur et al. [Quantitative analysis of sigma genes expression in Mycobacterium tuberculosis cultures exposed to rifampicin and isoniazid] Wiad. Lek. 2004
Interaction	Regulatory Rv1189	active	dreamsbeyondinfinity	2012-10-05
	Co-expression (Functional linkage) D. Homerova, L. Halgasova et al. Cascade of extracytoplasmic function sigma factors in Mycobacterium tuberculosis: identification of a sigmaJ-dependent promoter upstream of sigI. FEMS Microbiol. Lett. 2008
Interaction	Regulatory Rv0871	active	girishgene07	2012-10-05
	Co-expression (Functional linkage) K. Weldingh, A. Hansen et al. High resolution electroelution of polyacrylamide gels for the purification of single proteins from Mycobacterium tuberculosis culture filtrate. Scand. J. Immunol. 2000
Interaction	Regulatory Rv0871	active	girishgene07	2012-10-05
	Co-expression (Functional linkage) Y. Hu & AR. Coates Increased levels of sigJ mRNA in late stationary phase cultures of Mycobacterium tuberculosis detected by DNA array hybridisation. FEMS Microbiol. Lett. 2001
Interaction	Regulates Rv1094	active	yamir.moreno	2012-10-05
	One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. . M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009