Rv3339c - isocitrate dehydrogenase icd1
Protein Domains

Gene Information
LocusRv3339c
Symbolicd1
Gene Nameisocitrate dehydrogenase icd1
Location3724615 - 3725844 (-)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:1230 bp
Protein:410 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number32545
Related GenesAcel_0388 BL1499 MAP3455c MAV_4311 MT3442 nfa9230
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
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Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
TermEC:1.1.1.42 Isocitrate dehydrogenase (NADP(+)). - NRactiveextern:JZUCKER2012-03-06
Inferred from mutant phenotype
S. Banerjee, A. Nandyala et al. Comparison of Mycobacterium tuberculosis isocitrate dehydrogenases (ICD-1 and ICD-2) reveals differences in coenzyme affinity, oligomeric state, pH tolerance and phylogenetic affiliation. BMC Biochem. 2005
TermEC:4.1.1.- Lyases. Carbon-carbon lyases. Carboxy-lyases. - NRactiveextern:JZUCKER2012-03-06
Inferred from mutant phenotype
S. Banerjee, A. Nandyala et al. Comparison of Mycobacterium tuberculosis isocitrate dehydrogenases (ICD-1 and ICD-2) reveals differences in coenzyme affinity, oligomeric state, pH tolerance and phylogenetic affiliation. BMC Biochem. 2005
TermEC:1.1.1.- Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. - NRactiveextern:JZUCKER2012-03-06
Inferred from mutant phenotype
S. Banerjee, A. Nandyala et al. Comparison of Mycobacterium tuberculosis isocitrate dehydrogenases (ICD-1 and ICD-2) reveals differences in coenzyme affinity, oligomeric state, pH tolerance and phylogenetic affiliation. BMC Biochem. 2005
TermEC:1.1.1.42 Isocitrate dehydrogenase (NADP(+)). - NRactiveextern:JZUCKER2012-03-06
Traceable author statement to experimental support
authors,KY. Rhee,LP. de Carvalho,R. Bryk,S. Ehrt,J. Marrero,SW. Park,D. Schnappinger,A. Venugopal,C. Nathan Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier. Trends Microbiol. 2011
TermEC:4.1.1.- Lyases. Carbon-carbon lyases. Carboxy-lyases. - NRactiveextern:JZUCKER2012-03-06
Traceable author statement to experimental support
authors,KY. Rhee,LP. de Carvalho,R. Bryk,S. Ehrt,J. Marrero,SW. Park,D. Schnappinger,A. Venugopal,C. Nathan Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier. Trends Microbiol. 2011
TermEC:1.1.1.- Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. - NRactiveextern:JZUCKER2012-03-06
Traceable author statement to experimental support
authors,KY. Rhee,LP. de Carvalho,R. Bryk,S. Ehrt,J. Marrero,SW. Park,D. Schnappinger,A. Venugopal,C. Nathan Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier. Trends Microbiol. 2011