Rv3526 - oxidoreductase

Expression: Most Significant Conditions for Rv3526

Protein Domains

Gene Information
Locus	Rv3526
Symbol
Gene Name	oxidoreductase
Location	3962439 - 3963599 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1161 bp Protein:387 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	20239
Related Genes	MAV_0633 Mkms_4728 Mmcs_4640 MSMEG_5925 MUL_4089 Mvan_5225
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3526
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3526 Transcript 1
MSTDTSGVGVREIDAGALPTRYARGWHCLGVAKDYLEGKPHGVEAFGTKLVVFADSHGDL
KVLDGYCRHMGGDLSEGTVKGDEVACPFHDWRWGGDGRCKLVPYARRTPRMARTRSWTTD
VRSGLLFVWHDHEGNPPDPAVRIPEIPEAASDEWTDWRWNRILIEGSNCRDIIDNVTDMA
HFFYIHFGLPTYFKNVFEGHIASQYLHNVGRPDVDDLGTSYGEAHLDSEASYFGPSFMIN
WLHNRYGNYKSESILINCHYPVTQNSFVLQWGVIVEKPKGMSEEMTDKLSRVFTEGVSKG
FLQDVEIWKHKTRIDNPLLVEEDGAVYQLRRWYEQFYVDVADIKPEMVERFEIEVDTKRA
NEFWNAEVEKNLKSREVSDDVPAEQH*

Genomic Sequence

>Rv3526
GTGAGTACCGACACGAGTGGGGTCGGTGTTCGGGAGATCGATGCCGGCGCCTTGCCGACC
AGGTATGCGCGTGGCTGGCATTGCCTGGGCGTCGCGAAGGACTATTTGGAAGGGAAGCCA
CACGGGGTAGAGGCGTTCGGCACCAAGCTGGTTGTGTTCGCTGATTCCCACGGGGACCTG
AAAGTCCTCGACGGCTACTGCCGGCACATGGGCGGCGACCTGTCCGAGGGCACCGTCAAA
GGCGACGAGGTCGCTTGCCCGTTCCACGACTGGCGCTGGGGTGGCGACGGCCGCTGCAAA
TTGGTGCCGTATGCCAGGCGCACACCCAGAATGGCGCGCACTCGGTCGTGGACGACCGAT
GTGCGCAGCGGGCTGCTGTTTGTCTGGCACGACCATGAGGGCAATCCACCCGACCCCGCG
GTCCGGATCCCCGAGATTCCCGAGGCGGCCAGCGACGAGTGGACCGACTGGCGGTGGAAC
CGCATCCTCATCGAAGGGTCCAACTGCCGCGACATCATCGACAACGTCACCGATATGGCG
CACTTCTTCTACATCCACTTCGGTTTGCCGACGTACTTCAAGAACGTCTTCGAGGGCCAC
ATCGCCTCGCAGTATCTGCACAACGTGGGCCGGCCCGATGTCGACGATCTGGGGACGTCT
TACGGTGAGGCGCATCTGGATTCGGAGGCGTCTTACTTCGGGCCGTCGTTCATGATCAAC
TGGCTGCACAACCGCTACGGCAACTACAAGTCCGAGTCGATCCTGATCAACTGCCACTAC
CCGGTGACCCAGAACTCGTTCGTCCTGCAATGGGGCGTCATCGTCGAAAAGCCCAAGGGT
ATGAGCGAAGAGATGACCGACAAGTTGTCGCGGGTGTTCACCGAGGGCGTCAGCAAGGGC
TTCTTGCAGGATGTCGAGATCTGGAAGCACAAGACCCGCATCGACAACCCGCTGCTGGTT
GAAGAGGACGGCGCCGTGTATCAGCTGCGCCGCTGGTATGAACAGTTTTATGTCGACGTA
GCCGACATAAAACCAGAGATGGTGGAGCGCTTCGAGATCGAGGTCGACACCAAGCGCGCC
AACGAGTTCTGGAATGCCGAGGTAGAGAAGAACTTGAAATCGAGAGAAGTTTCCGACGAC
GTGCCCGCCGAGCAACACTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv3574	active	jgalag	2012-10-05
	Co-expression (Functional linkage) SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	RegulatedBy Rv3574	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Term	EC:1.14.13.- Oxidoreductases. Acting on paired donors, with incorporation or reduction of With NADH or NADPH as one donor, and incorporation of one atom - NR	active	nsampson	2012-03-05
	Assay of protein purified to homogeneity from a heterlogous host JK. Capyk,I. D'Angelo,NC. Strynadka,LD. Eltis Characterization of 3-ketosteroid 9{alpha}-hydroxylase, a Rieske oxygenase in the cholesterol degradation pathway of Mycobacterium tuberculosis. J. Biol. Chem. 2009
Name	3-ketosteroid hydroxylase, oxygenase	active	cstolte	2011-01-03
	Capyk (2009) - KshA catalyzes the addition of oxygen molecules (oxygenase) while KshB provides reducing equivilants (reductase). KshA was not saturated with KshB even at 10-fold excess of B promoter over A.
Symbol	KshA	active	cstolte	2011-01-03
	Capyk (2009) - KshA catalyzes the addition of oxygen molecules (oxygenase) while KshB provides reducing equivilants (reductase). KshA was not saturated with KshB even at 10-fold excess of B promoter over A.
Name	3-ketosteroid hydroxylase, oxygenase	active	jgalag	2010-09-02
	Capyk (2009) - KshA catalyzes the addition of oxygen molecules (oxygenase) while KshB provides reducing equivilants (reductase). KshA was not saturated with KshB even at 10-fold excess of B promoter over A.
Symbol	KshA	active	jgalag	2010-09-02
	Capyk (2009) - KshA catalyzes the addition of oxygen molecules (oxygenase) while KshB provides reducing equivilants (reductase). KshA was not saturated with KshB even at 10-fold excess of B promoter over A.