Rv3537 - dehydrogenase
Protein Domains

Gene Information
LocusRv3537
Symbol
Gene Namedehydrogenase
Location3975369 - 3977060 (+)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:1692 bp
Protein:564 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number19070
Related GenesMAP0530c MAV_0624 Mkms_4750 Mmcs_4662 MSMEG_5941 MT3641 MUL_4098 Mvan_5237 nfa4630 SAV1595
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
Search for regulators of Rv3537
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionRegulatory Rv3574activepriyadarshinipriyanka20012012-10-05
Co-expression (Functional linkage)
SL. Kendall,P. Burgess,R. Balhana,M. Withers,A. Ten Bokum,JS. Lott,C. Gao,I. Uhia Castro,NG. Stoker Cholesterol utilisation in mycobacteria is controlled by two TetR-type transcriptional regulators; kstR and kstR2. Microbiology (Reading, England) 2010
InteractionRegulatory Rv3574activepriyadarshinipriyanka20012012-10-05
Co-expression (Functional linkage)
SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
InteractionRegulatedBy Rv3416activeyamir.moreno2012-10-05
One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. .
M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
InteractionRegulatedBy Rv3414cactiveyamir.moreno2012-10-05
One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. .
M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
InteractionRegulatedBy Rv2021cactiveyamir.moreno2012-10-05
One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. .
M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
InteractionRegulatedBy Rv1956activeyamir.moreno2012-10-05
One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. .
M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
InteractionRegulatedBy Rv0491activeyamir.moreno2012-10-05
One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. .
M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
InteractionRegulatedBy Rv0117activeyamir.moreno2012-10-05
One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. .
M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
InteractionRegulatedBy Rv3574activeyamir.moreno2012-10-05
M.smegmatis orthology based inference. Orthologous pair regulator-target found in M.smegmatis.
SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
TermEC:1.3.99.4 3-oxosteroid 1-dehydrogenase. - NRactiveextern:JZUCKER2012-03-06
Assay of protein purified to homogeneity from its native host
J. Knol, K. Bodewits et al. 3-Keto-5alpha-steroid Delta(1)-dehydrogenase from Rhodococcus erythropolis SQ1 and its orthologue in Mycobacterium tuberculosis H37Rv are highly specific enzymes that function in cholesterol catabolism. Biochem. J. 2008
TermEC:1.3.99.4 3-oxosteroid 1-dehydrogenase. - NRactivensampson2012-03-05
Assay of protein purified to homogeneity from a heterlogous host
authors,JK. Capyk,I. Casabon,R. Gruninger,NC. Strynadka,LD. Eltis Activity of 3-ketosteroid 9±-hydroxylase (KshAB) indicates cholesterol side chain and ring degradation occur simultaneously in Mycobacterium tuberculosis. J. Biol. Chem. 2011
Name3-ketosteroid delta(1)-dehydrogenaseactivecstolte2011-01-03
Knol (2008)
SymbolKstDactivecstolte2011-01-03
Knol (2008)
Name3-ketosteroid delta(1)-dehydrogenaseactivejgalag2010-09-02
Knol (2008)
SymbolKstDactivejgalag2010-09-02
Knol (2008)