Rv3539 - PPE family protein

Expression: Most Significant Conditions for Rv3539

Protein Domains

Gene Information
Locus	Rv3539
Symbol	PPE63
Gene Name	PPE family protein
Location	3978059 - 3979498 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1440 bp Protein:480 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	12705
Related Genes	MAP2234 MAV_1760 ML1232 MT1221 MT3643 Rv1184c
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3539
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3539 Transcript 1
MADFLTLSPEVNSARMYAGGGPGSLSAAAAAWDELAAELWLAAASFESVCSGLADRWWQG
PSSRMMAAQAARHTGWLAAAATQAEGAASQAQTMALAYEAAFAATVHPALVAANRALVAW
LAGSNVFGQNTPAIAAAEAIYEQMWAQDVVAMLNYHAVASAVGARLRPWQQLLHELPRRL
GGEHSDSTNTELANPSSTTTRITVPGASPVHAATLLPFIGRLLAARYAELNTAIGTNWFP
GTTPEVVSYPATIGVLSGSLGAVDANQSIAIGQQMLHNEILAATASGQPVTVAGLSMGSM
VIDRELAYLAIDPNAPPSSALTFVELAGPERGLAQTYLPVGTTIPIAGYTVGNAPESQYN
TSVVYSQYDIWADPPDRPWNLLAGANALMGAAYFHDLTAYAAPQQGIEIAAVTSSLGGTT
TTYMIPSPTLPLLLPLKQIGVPDWIVGGLNNVLKPLVDAGYSQYAPTAGPYFSHGNLVW*

Genomic Sequence

>Rv3539
ATGGCGGATTTCTTGACGTTGTCACCAGAGGTGAATTCGGCCCGGATGTACGCGGGTGGG
GGGCCCGGGTCGCTATCGGCGGCCGCGGCGGCCTGGGATGAGTTGGCCGCCGAACTGTGG
TTGGCGGCGGCCTCGTTCGAGTCGGTGTGCTCCGGCCTGGCGGACCGTTGGTGGCAAGGG
CCGTCGTCTCGGATGATGGCGGCGCAGGCCGCCCGCCATACGGGGTGGCTGGCCGCGGCG
GCCACCCAGGCAGAGGGAGCAGCCAGCCAGGCTCAGACGATGGCGCTGGCCTATGAAGCG
GCGTTCGCCGCAACCGTACACCCGGCGCTGGTCGCGGCGAACCGCGCCCTCGTGGCCTGG
TTGGCGGGGTCGAATGTGTTCGGGCAGAACACCCCGGCGATTGCGGCCGCCGAGGCCATC
TACGAGCAGATGTGGGCTCAGGATGTTGTCGCGATGTTGAACTACCATGCGGTGGCCTCG
GCGGTCGGGGCGCGGTTGCGGCCGTGGCAGCAGTTGCTGCATGAGCTGCCCAGGCGGTTG
GGCGGCGAACACTCCGACAGCACAAACACGGAACTCGCTAACCCGAGTTCAACGACGACA
CGCATTACCGTCCCCGGCGCATCTCCGGTGCATGCAGCGACGTTACTGCCGTTCATCGGA
AGGCTACTGGCGGCGCGTTATGCCGAGCTGAACACCGCGATCGGCACGAACTGGTTTCCG
GGCACCACGCCAGAAGTGGTGAGCTATCCGGCCACCATCGGGGTCCTTAGCGGCTCTCTT
GGCGCCGTCGATGCCAACCAGTCCATCGCTATCGGTCAGCAGATGTTGCACAACGAGATC
CTGGCCGCCACGGCCTCCGGTCAGCCGGTGACGGTGGCCGGACTGTCGATGGGCAGCATG
GTCATCGACCGCGAACTTGCCTATCTGGCCATCGACCCCAACGCGCCACCCTCGAGCGCG
CTCACATTCGTCGAGCTCGCCGGCCCGGAACGCGGTCTTGCCCAGACCTACCTGCCCGTT
GGCACCACCATTCCAATCGCGGGGTACACCGTGGGGAATGCGCCCGAGAGCCAGTACAAC
ACCAGCGTGGTTTATAGCCAGTACGATATCTGGGCCGATCCGCCCGACCGTCCGTGGAAC
CTGTTGGCCGGCGCCAACGCACTGATGGGCGCGGCTTACTTTCACGATCTGACCGCCTAC
GCCGCACCACAACAGGGGATAGAGATCGCCGCTGTCACGAGTTCACTGGGCGGAACCACG
ACAACGTACATGATTCCGTCGCCCACGCTGCCGTTGCTGTTGCCACTGAAGCAGATCGGT
GTCCCAGACTGGATCGTCGGCGGGCTGAACAACGTGCTGAAGCCGCTCGTCGACGCGGGC
TACTCACAGTACGCCCCCACCGCCGGCCCTTATTTCAGCCACGGCAACCTGGTGTGGTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv0109	active	prabhakarsmail	2012-10-05
	Co-expression (Functional linkage) authors,R. Riley,M. Pellegrini,D. Eisenberg Identifying cognate binding pairs among a large set of paralogs: the case of PE/PPE proteins of Mycobacterium tuberculosis. PLoS Comput. Biol. 2008
Interaction	RegulatedBy Rv1221	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008