Rv3610c - membrane-bound ell division protein ftsH

Expression: Most Significant Conditions for Rv3610c

Protein Domains

Gene Information
Locus	Rv3610c
Symbol	ftsH
Gene Name	membrane-bound ell division protein ftsH
Location	4050601 - 4052883 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:2283 bp Protein:761 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	24787
Related Genes	Acel_0204 BL1682 CE2542 cg2984 DIP2002 jk0278 MAP0448 MAV_0542 Mkms_4856 ML0222 Mmcs_4770 MSMEG_6105 MT3714 MUL_4192 Mvan_5372 nfa3980 PPA0260 SAV4666
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3610c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3610c Transcript 1
MNRKNVTRTITAIAVVVLLGWSFFYFSDDTRGYKPVDTSVAITQINGDNVKSAQIDDREQ
QLRLILKKGNNETDGSEKVITKYPTGYAVDLFNALSAKNAKVSTVVNQGSILGELLVYVL
PLLLLVGLFVMFSRMQGGARMGFGFGKSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKD
FLQNPSRYQALGAKIPKGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVG
ASRVRDLFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFGDRA
GVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLRVHSKGKPMAADADLDGL
AKRTVGMTGADLANVINEAALLTARENGTVITGPALEEAVDRVIGGPRRKGRIISEQEKK
ITAYHEGGHTLAAWAMPDIEPIYKVTILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFA
MGGRAAEELVFREPTTGAVSDIEQATKIARSMVTEFGMSSKLGAVKYGSEHGDPFLGRTM
GTQPDYSHEVAREIDEEVRKLIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRPELES
IFADVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPQPVPEPAFKAAIAQATQ
AAEAARSDAGQTGHGANGSPAGTHRSGDRQYGSTQPDYGAPAGWHAPGWPPRSSHRPSYS
GEPAPTYPGQPYPTGQADPGSDESSAEQDDEVSRTKPAHG*

Genomic Sequence

>Rv3610c
ATGAACCGGAAAAACGTGACTCGCACCATAACAGCGATCGCCGTCGTGGTGCTGCTCGGC
TGGTCGTTCTTTTACTTCAGCGACGACACCCGCGGCTACAAGCCCGTTGATACCTCGGTG
GCGATAACACAGATCAACGGCGACAACGTCAAGAGCGCACAGATCGACGATCGCGAGCAA
CAGCTGCGGCTGATCCTGAAGAAGGGTAACAACGAGACCGACGGGTCCGAGAAGGTCATC
ACCAAGTACCCCACCGGGTACGCCGTCGACCTGTTCAACGCGCTCAGCGCCAAAAACGCG
AAGGTCAGCACGGTCGTCAACCAGGGCAGCATCCTGGGCGAGCTGCTGGTCTACGTGCTG
CCGCTGCTGTTGCTGGTGGGGCTGTTCGTGATGTTCTCCCGCATGCAAGGCGGCGCCCGG
ATGGGCTTCGGGTTCGGCAAGTCACGCGCCAAGCAACTGAGCAAGGACATGCCCAAGACC
ACCTTCGCCGACGTCGCAGGTGTCGACGAGGCGGTCGAGGAGCTCTACGAGATCAAGGAC
TTCCTGCAGAACCCCAGCAGGTACCAAGCGCTGGGCGCCAAGATCCCCAAAGGCGTGCTG
CTCTACGGGCCGCCGGGAACCGGTAAGACGTTGCTGGCTCGTGCGGTGGCCGGCGAAGCC
GGAGTGCCGTTCTTCACCATCTCCGGCTCCGACTTCGTCGAAATGTTCGTCGGCGTCGGC
GCATCCCGTGTCAGAGACCTGTTCGAGCAGGCCAAGCAGAACAGCCCGTGCATCATCTTC
GTCGACGAGATCGACGCCGTCGGCCGACAAAGAGGCGCCGGGCTGGGCGGCGGTCACGAC
GAGCGTGAGCAGACCCTCAACCAGTTGCTAGTCGAAATGGACGGTTTTGGCGATCGCGCC
GGCGTCATCCTGATCGCGGCCACCAACCGGCCCGACATCCTGGACCCGGCGCTGTTGCGG
CCGGGCCGCTTCGACCGCCAGATCCCGGTATCCAACCCCGATCTGGCGGGTCGGCGGGCG
GTGCTGCGCGTGCACTCCAAGGGCAAGCCGATGGCCGCGGACGCCGACCTCGACGGACTG
GCCAAGCGGACCGTCGGCATGACCGGAGCCGACCTGGCCAACGTCATCAACGAGGCGGCG
CTGCTGACCGCCCGGGAGAACGGCACCGTCATCACCGGTCCCGCCCTCGAGGAAGCGGTG
GACCGGGTGATCGGCGGCCCGCGCCGCAAAGGCCGGATCATCAGCGAGCAGGAGAAGAAG
ATCACCGCCTATCACGAGGGCGGGCACACCCTGGCCGCTTGGGCGATGCCCGATATCGAG
CCGATTTATAAGGTGACGATCCTGGCGCGCGGGCGTACCGGCGGGCACGCGGTGGCGGTG
CCGGAAGAAGACAAGGGCCTGCGGACCCGCTCGGAAATGATCGCGCAACTGGTGTTCGCG
ATGGGTGGGCGCGCCGCCGAAGAACTGGTGTTTCGTGAGCCGACCACCGGCGCGGTGTCC
GACATCGAGCAGGCCACCAAGATAGCGCGCTCAATGGTCACCGAATTTGGAATGAGCTCC
AAGCTGGGCGCGGTCAAATACGGCTCCGAACACGGCGACCCGTTCCTCGGACGTACCATG
GGCACCCAGCCGGACTACTCCCACGAGGTCGCCCGCGAGATCGACGAAGAGGTCCGCAAG
CTTATCGAGGCGGCGCATACCGAAGCGTGGGAAATCCTGACCGAATACCGCGACGTGCTG
GACACTTTGGCCGGCGAGCTGCTGGAAAAGGAGACCCTGCACCGACCCGAGCTGGAAAGC
ATCTTCGCTGACGTCGAAAAGCGGCCGCGGCTCACCATGTTCGACGACTTCGGTGGCCGG
ATCCCGTCGGACAAACCGCCCATCAAGACACCCGGCGAGCTCGCGATCGAACGCGGCGAA
CCTTGGCCCCAGCCGGTCCCCGAGCCGGCGTTCAAGGCGGCGATTGCGCAGGCTACCCAA
GCCGCTGAGGCCGCCCGGTCCGACGCCGGCCAAACCGGGCACGGCGCCAACGGTTCGCCC
GCCGGCACCCACCGGTCCGGTGACCGCCAGTACGGCTCCACCCAGCCTGACTACGGTGCC
CCGGCGGGCTGGCATGCGCCGGGATGGCCCCCAAGGTCATCTCATCGGCCCAGCTATAGC
GGTGAACCGGCACCGACGTATCCGGGTCAGCCCTACCCGACCGGTCAAGCCGATCCGGGT
TCCGATGAGTCCTCGGCGGAGCAGGATGACGAGGTCAGTCGGACCAAGCCGGCCCACGGC
TGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Translation Rv2150c	active	shahanup86	2012-10-05
	Affinity purification (Physical interaction) G. Anilkumar, R. Srinivasan et al. Genomic organization and in vivo characterization of proteolytic activity of FtsH of Mycobacterium smegmatis SN2. Microbiology (Reading, Engl.) 2004
Interaction	Translation Rv0732	active	shahanup86	2012-10-05
	Affinity purification (Physical interaction) G. Anilkumar, R. Srinivasan et al. Genomic organization and in vivo characterization of proteolytic activity of FtsH of Mycobacterium smegmatis SN2. Microbiology (Reading, Engl.) 2004
Interaction	Translation Rv2150c	active	shahanup86	2012-10-05
	Affinity purification (Physical interaction) authors,G. Anilkumar,R. Srinivasan,SP. Anand,P. Ajitkumar Bacterial cell division protein FtsZ is a specific substrate for the AAA family protease FtsH. Microbiology (Reading, Engl.) 2001
Interaction	Translation Rv0732	active	shahanup86	2012-10-05
	Affinity purification (Physical interaction) authors,G. Anilkumar,R. Srinivasan,SP. Anand,P. Ajitkumar Bacterial cell division protein FtsZ is a specific substrate for the AAA family protease FtsH. Microbiology (Reading, Engl.) 2001
Interaction	Translation Rv2150c	active	shahanup86	2012-10-05
	Affinity purification (Physical interaction) authors,R. Srinivasan,H. Rajeswari,P. Ajitkumar Analysis of degradation of bacterial cell division protein FtsZ by the ATP-dependent zinc-metalloprotease FtsH in vitro. Microbiol. Res. 2008
Interaction	Translation Rv0732	active	shahanup86	2012-10-05
	Affinity purification (Physical interaction) authors,R. Srinivasan,H. Rajeswari,P. Ajitkumar Analysis of degradation of bacterial cell division protein FtsZ by the ATP-dependent zinc-metalloprotease FtsH in vitro. Microbiol. Res. 2008
Interaction	Translation Rv2150c	active	shahanup86	2012-10-05
	Affinity purification (Physical interaction) G. Anilkumar, MM. Chauhan et al. Cloning and expression of the gene coding for FtsH protease from Mycobacterium tuberculosis H37Rv. Gene 1998
Interaction	Translation Rv0732	active	shahanup86	2012-10-05
	Affinity purification (Physical interaction) G. Anilkumar, MM. Chauhan et al. Cloning and expression of the gene coding for FtsH protease from Mycobacterium tuberculosis H37Rv. Gene 1998
Interaction	Translation Rv2150c	active	shahanup86	2012-10-05
	Affinity purification (Physical interaction) authors,C. Herman,D. Thévenet,R. D'Ari,P. Bouloc Degradation of sigma 32, the heat shock regulator in Escherichia coli, is governed by HflB. Proc. Natl. Acad. Sci. U.S.A. 1995
Interaction	Translation Rv0732	active	shahanup86	2012-10-05
	Affinity purification (Physical interaction) authors,C. Herman,D. Thévenet,R. D'Ari,P. Bouloc Degradation of sigma 32, the heat shock regulator in Escherichia coli, is governed by HflB. Proc. Natl. Acad. Sci. U.S.A. 1995
Interaction	Translation Rv2150c	active	shahanup86	2012-10-05
	Affinity purification (Physical interaction) authors,H. Zheng,L. Lu,B. Wang,S. Pu,X. Zhang,G. Zhu,W. Shi,L. Zhang,H. Wang,S. Wang,G. Zhao,Y. Zhang Genetic basis of virulence attenuation revealed by comparative genomic analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv. PLoS ONE 2008
Interaction	Translation Rv0732	active	shahanup86	2012-10-05
	Affinity purification (Physical interaction) authors,H. Zheng,L. Lu,B. Wang,S. Pu,X. Zhang,G. Zhu,W. Shi,L. Zhang,H. Wang,S. Wang,G. Zhao,Y. Zhang Genetic basis of virulence attenuation revealed by comparative genomic analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv. PLoS ONE 2008
Interaction	Translation Rv2150c	active	shahanup86	2012-10-05
	Affinity purification (Physical interaction) R. Srinivasan, G. Anilkumar et al. Functional characterization of AAA family FtsH protease of Mycobacterium tuberculosis. FEMS Microbiol. Lett. 2006
Interaction	Translation Rv0732	active	shahanup86	2012-10-05
	Affinity purification (Physical interaction) R. Srinivasan, G. Anilkumar et al. Functional characterization of AAA family FtsH protease of Mycobacterium tuberculosis. FEMS Microbiol. Lett. 2006
Name	Quality control membrane protease	active	mjackson	2012-10-05
	Cell division
Name	Quality control membrane protease	active	mjackson	2012-10-05
	Cell division