Rv3634c - UDP-glucose 4-epimerase galE1

Expression: Most Significant Conditions for Rv3634c

Protein Domains

Gene Information
Locus	Rv3634c
Symbol	galE1
Gene Name	UDP-glucose 4-epimerase galE1
Location	4072667 - 4073611 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:945 bp Protein:315 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	35594
Related Genes	CE0333 cg0391 MAP0430 MAV_0524 Mkms_4875 ML0204 Mmcs_4789 MSMEG_6142 MT3736 MUL_4210 Mvan_5389
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3634c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3634c Transcript 1
MRALVTGAAGFIGSTLVDRLLADGHSVVGLDNFATGRATNLEHLADNSAHVFVEADIVTA
DLHAILEQHRPEVVFHLAAQIDVRRSVADPQFDAAVNVIGTVRLAEAARQTGVRKIVHTS
SGGSIYGTPPEYPTPETAPTDPASPYAAGKVAGEIYLNTFRHLYGLDCSHIAPANVYGPR
QDPHGEAGVVAIFAQALLSGKPTRVFGDGTNTRDYVFVDDVVDAFVRVSADVGGGLRFNI
GTGKETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDIGLAERVLGWRPQIELADG
VRRTVEYFRHKHTD*

Genomic Sequence

>Rv3634c
GTGCGCGCACTGGTCACTGGGGCGGCCGGATTCATCGGCTCGACGTTAGTCGACCGGTTG
CTGGCAGATGGTCATTCGGTGGTGGGATTGGACAACTTCGCGACCGGCCGGGCGACCAAC
CTCGAGCATCTGGCCGACAACTCCGCACACGTCTTCGTCGAAGCCGACATTGTGACCGCC
GATCTACACGCCATCCTCGAGCAGCACCGGCCCGAGGTGGTATTTCACCTGGCGGCCCAG
ATCGATGTCCGCCGTTCGGTGGCTGACCCGCAATTCGACGCCGCGGTCAATGTCATCGGC
ACGGTGCGCCTAGCCGAGGCCGCGCGGCAGACCGGTGTCCGCAAGATCGTGCACACCTCC
TCGGGAGGATCGATCTATGGCACCCCGCCGGAGTATCCAACCCCTGAGACAGCGCCCACC
GATCCGGCCTCGCCGTATGCCGCGGGCAAAGTGGCCGGCGAAATCTACCTGAACACCTTT
CGACATCTCTACGGCCTGGACTGCTCGCATATCGCACCGGCTAACGTCTACGGTCCTCGC
CAGGACCCACACGGTGAAGCGGGTGTGGTAGCGATCTTCGCGCAGGCGCTGCTCTCGGGC
AAACCCACCAGGGTGTTCGGCGACGGCACCAATACGCGCGACTATGTGTTTGTCGACGAC
GTGGTCGACGCGTTTGTCCGGGTGTCCGCGGACGTCGGCGGTGGGCTGCGCTTCAACATC
GGCACCGGTAAGGAAACGTCGGACCGCCAACTGCATTCGGCGGTGGCCGCGGCTGTCGGC
GGGCCCGACGACCCTGAGTTCCACCCGCCGCGGCTAGGCGATCTTAAGCGGTCCTGCCTT
GACATCGGCTTAGCCGAACGGGTTTTGGGCTGGCGTCCGCAGATCGAGTTGGCCGACGGC
GTGCGTCGCACGGTCGAGTACTTCCGGCACAAGCACACTGATTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv1221	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. PA. Fontán, V. Aris et al. Mycobacterium tuberculosis Sigma Factor E Regulon Modulates the Host Inflammatory Response. J. Infect. Dis. 2008
Interaction	RegulatedBy Rv3676	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv3676	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006
Name	UDP-Glucose-4-epimerase: formation of UDP-Galactopyranosem, the first step in the formation of UDP-Galactofuranose the donor of galactofuranosyl residues	active	mjackson	2012-10-05
	UDP-Galactofuranose synthesis
Term	EC:5.1.3.2 UDP-glucose 4-epimerase. - NR	active	extern:JZUCKER	2012-03-06
	Assay of protein purified to homogeneity from its native host A. Weston,RJ. Stern,RE. Lee,PM. Nassau,D. Monsey,SL. Martin,MS. Scherman,GS. Besra,K. Duncan,MR. McNeil Biosynthetic origin of mycobacterial cell wall galactofuranosyl residues. Tuber. Lung Dis. 1997
Term	GO:0009226 nucleotide-sugar biosynthetic process - NR	active	mmcneil	2012-03-05
	UDP-Glucose-4-epimerase: formation of UDP-Galp the first step in the formation of UDP-Galf the donor of galactofuranosyl residues. Standard pathway; enzymatic evidence A. Weston,RJ. Stern,RE. Lee,PM. Nassau,D. Monsey,SL. Martin,MS. Scherman,GS. Besra,K. Duncan,MR. McNeil Biosynthetic origin of mycobacterial cell wall galactofuranosyl residues. Tuber. Lung Dis. 1997