Rv3783 - O-antigen/lipopolysaccharide transport membrane protein ABC transporter rfbD

Expression: Most Significant Conditions for Rv3783

Protein Domains

Gene Information
Locus	Rv3783
Symbol	rfbD
Gene Name	O-antigen/lipopolysaccharide transport membrane protein ABC transporter rfbD
Location	4229258 - 4230100 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:843 bp Protein:281 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	32475
Related Genes	BL0208 CE0178 cg0249 DIP0175 jk2036 MAP0239c MAV_0236 Mkms_5081 ML0112 Mmcs_4993 MSMEG_6369 MT3892 MUL_0090 Mvan_5620 nfa2190 SAV5081
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3783
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3783 Transcript 1
MTFMDAQASFQTQSRTLARVRGDLVDGFRRHELWLHLGWQDIKQRYRRSVLGPFWITIAT
GTTAVAMGGLYSKLFRLELSEHLPYVTLGLIVWNLINAAILDGAEVFVANEGLIKQLPAP
LSVHVYRLVWRQMIFFAHNIVIYFVIAIIFPKPWSWADLSFLPALALIFLNCVWVSLCFG
ILATRYRDIGPLLFSVVQLLFFMTPIIWNDETLRRQGAGRWSSIVELNPLLHYLDIVRAP
LLGAHQELRHWLVVLVLTVVGWMLAAFAMRQYRARVPYWV*

Genomic Sequence

>Rv3783
ATGACATTCATGGATGCTCAAGCTAGCTTCCAGACACAGTCGCGGACACTGGCCCGCGTC
CGAGGCGATCTGGTCGACGGGTTCCGCCGCCACGAGCTGTGGCTGCACCTGGGCTGGCAG
GACATCAAGCAGCGGTACCGCCGCTCGGTGCTGGGGCCGTTCTGGATCACCATCGCCACC
GGAACGACCGCCGTCGCGATGGGCGGCCTGTATTCCAAGCTGTTTCGGCTCGAGCTGTCT
GAGCACCTGCCCTACGTCACGCTCGGGCTGATCGTCTGGAACCTGATCAACGCCGCCATC
CTGGACGGCGCAGAGGTTTTCGTCGCCAACGAAGGTCTGATCAAACAGCTGCCGGCACCG
TTGAGCGTGCACGTCTATCGGTTGGTGTGGCGGCAGATGATCTTCTTCGCCCACAACATC
GTCATCTACTTCGTCATCGCGATCATCTTTCCTAAGCCGTGGTCGTGGGCGGATCTGTCG
TTTCTTCCGGCGCTGGCGCTCATTTTCCTCAATTGCGTTTGGGTGTCACTGTGTTTCGGC
ATCCTGGCGACCCGCTACCGCGACATCGGCCCGCTGCTGTTTTCCGTTGTGCAGTTGTTG
TTCTTCATGACGCCGATCATCTGGAACGACGAGACCCTGCGTCGGCAGGGCGCGGGCCGC
TGGTCGAGCATCGTCGAGCTCAACCCGCTGCTGCACTATCTGGACATCGTGCGGGCGCCA
CTGTTGGGCGCTCACCAGGAGCTGCGGCACTGGCTGGTGGTGCTGGTGTTGACCGTCGTC
GGCTGGATGCTGGCGGCGTTCGCGATGCGGCAGTATCGCGCGCGGGTGCCCTACTGGGTG
TAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv0348	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. B. Abomoelak, EA. Hoye et al. mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2009
Term	GO:0015159 polysaccharide transmembrane transporter activity - NR	active	mmcneil	2012-03-05
	ABC-transporter likely to be involved in the translocation of arabinogalactan precursors across the plasma membrane; membrane-spanning protein (phenotypic [mycobacterial recombinant strains]) authors,P. Dianiaková,J. Korduláková,H. Skovierová,D. Kaur,M. Jackson,PJ. Brennan,K. Mikuaová Investigation of ABC transporter from mycobacterial arabinogalactan biosynthetic cluster. Gen. Physiol. Biophys. 2011