Rv3820c - polyketide synthase associated protein papA2

Expression: Most Significant Conditions for Rv3820c

Protein Domains

Gene Information
Locus	Rv3820c
Symbol	papA2
Gene Name	polyketide synthase associated protein papA2
Location	4284419 - 4285825 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1407 bp Protein:469 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	19830
Related Genes	MAP3721 MAP3763c MAV_2005 MAV_4883 Mkms_3178 Mmcs_3118 MSMEG_4728 MT3928 MT3932 nfa30230 Rv3824c
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3820c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3820c Transcript 1
MFSITTLRDWTPDPGSIICWHASPTAKAKARQAPISEVPPSYQQAQHLRRYRDHVARGLD
MSRLMIFTWDLPGRCNIRAMNYAINAHLRRHDTYHSWFEFDNAEHIVRHTIADPADIEVV
QAEHQNMTSAELRHHIATPQPLQWDCFLFGIIQSDDHFTFYASIAHLCVDPMIVGVLFIE
IHMMYSALVGGDPPIELPPAGRYDDHCVRQYADTAALTLDSARVRRWVEFAANNDGTLPH
FPLPLGDLSVPHTGKLLTETLMDEQQGERFEAACVAAGARFSGGVFACAALAERELTNCE
TFDVVTTTDTRRTPTELRTTGWFTGLVPITVPVASGLFDSAARVAQISFDSGKDLATVPF
DRVLELARPETGLRPPRPGNFVMSFLDASIAPLSTVANSDLNFRIYDEGRVSHQVSMWVN
RYQHQTTVTVLFPDNPIASESVANYIAAMKSIYIRTADGTLATLKPGT*

Genomic Sequence

>Rv3820c
GTGTTTAGCATTACAACGCTCCGCGACTGGACGCCGGACCCAGGTTCGATTATCTGTTGG
CACGCATCACCGACGGCGAAGGCGAAAGCCCGGCAAGCGCCGATAAGTGAGGTGCCGCCC
AGCTATCAACAAGCTCAACACCTTCGACGTTATCGCGATCATGTAGCGCGCGGTCTCGAT
ATGTCGCGCCTGATGATCTTCACCTGGGATCTACCTGGCCGGTGCAACATCCGCGCCATG
AATTATGCGATCAACGCACACCTTCGCCGCCACGACACCTACCACAGTTGGTTTGAGTTC
GACAATGCCGAACACATCGTTCGGCATACCATCGCTGACCCTGCAGATATCGAAGTCGTC
CAAGCTGAGCATCAGAACATGACGTCGGCGGAGCTGCGCCACCACATTGCAACGCCGCAG
CCGTTGCAGTGGGACTGCTTCTTGTTCGGGATTATTCAGAGTGACGATCACTTCACCTTC
TATGCGAGTATCGCTCATCTCTGTGTCGATCCGATGATTGTGGGCGTCCTTTTCATCGAG
ATCCATATGATGTACTCCGCATTGGTGGGAGGCGACCCGCCGATCGAGCTCCCGCCGGCG
GGCCGCTACGACGACCACTGTGTCCGACAGTACGCCGACACGGCCGCCTTGACGTTGGAC
TCCGCCCGGGTGCGCCGTTGGGTCGAATTCGCTGCCAACAACGACGGAACCCTGCCGCAC
TTCCCGTTGCCGCTCGGCGATCTATCGGTGCCCCATACCGGAAAGCTGCTTACCGAAACG
CTGATGGACGAGCAACAGGGCGAGCGATTCGAAGCCGCCTGCGTCGCTGCGGGCGCCCGT
TTTAGCGGTGGCGTTTTCGCCTGCGCCGCCCTCGCTGAGCGCGAGTTGACCAACTGTGAA
ACGTTTGACGTGGTAACGACGACTGATACACGTAGGACGCCGACAGAACTCAGAACGACG
GGCTGGTTTACCGGGTTGGTGCCGATCACCGTGCCGGTCGCCTCAGGACTTTTCGATAGC
GCCGCCCGTGTCGCGCAGATCTCCTTCGATTCGGGTAAGGACCTGGCGACCGTACCATTC
GACCGCGTATTGGAGCTGGCACGCCCCGAAACGGGGCTGAGGCCGCCCCGGCCGGGCAAT
TTCGTGATGTCCTTTCTGGATGCCAGCATTGCGCCTCTTTCTACGGTCGCTAATTCCGAT
CTGAATTTTAGGATTTACGACGAAGGTAGGGTTTCTCATCAGGTCTCGATGTGGGTCAAT
CGGTATCAGCATCAGACCACAGTGACGGTATTATTCCCGGACAACCCGATCGCAAGCGAA
TCCGTCGCCAATTACATCGCGGCCATGAAATCCATCTATATCCGCACCGCCGACGGCACG
CTCGCGACACTTAAACCAGGCACATGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Name	Acyltransferase responsible for the palmitoylation of trehalose-2-sulfate at the 2'-position (using palmitoyl-CoA) to form trehalose-2-sulfate-2'-palmitate	active	mjackson	2012-10-05
	Polymethyl-branched acyltrehaloses
Name	Acyltransferase responsible for the palmitoylation of trehalose-2-sulfate at the 2'-position (using palmitoyl-CoA) to form trehalose-2-sulfate-2'-palmitate	active	mjackson	2012-10-05
	Polymethyl-branched acyltrehaloses
Other	TBPWY:Polymethyl-branched acyltrehaloses	active	mjackson	2012-03-05
	Acyltransferase responsible for the palmitoylation of trehalose-2-sulfate at the 2'-position (using palmitoyl-CoA) to form trehalose-2-sulfate-2'-palmitate (phenotypic [mycobacterial recombinant strains]; enzymatic) P. Kumar, MW. Schelle et al. PapA1 and PapA2 are acyltransferases essential for the biosynthesis of the Mycobacterium tuberculosis virulence factor sulfolipid-1. Proc. Natl. Acad. Sci. U.S.A. 2007