Rv1013 - polyketide synthase pks16

Expression: Most Significant Conditions for Rv1013

Protein Domains

Gene Information
Locus	Rv1013
Symbol	pks16
Gene Name	polyketide synthase pks16
Location	1131625 - 1133259 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1635 bp Protein:545 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	26658
Related Genes	MAP0977 MAV_1150 Mkms_4347 ML0243 Mmcs_4261 MSMEG_5435 MT1041 MUL_4648 Mvan_4798 nfa48910
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1013
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1013 Transcript 1
MSRFTEKMFHNARTATTGMVTGEPHMPVRHTWGEVHERARCIAGGLAAAGVGLGDVVGVL
AGFPVEIAPTAQALWMRGASLTMLHQPTPRTDLAVWAEDTMTVIGMIEAKAVIVSEPFLV
AIPILEQKGMQVLTVADLLASDPIGPIEVGEDDLALMQLTSGSTGSPKAVQITHRNIYSN
AEAMFVGAQYDVDKDVMVSWLPCFHDMGMVGFLTIPMFFGAELVKVTPMDFLRDTLLWAK
LIDKYQGTMTAAPNFAYALLAKRLRRQAKPGDFDLSTLRFALSGAEPVEPADVEDLLDAG
KPFGLRPSAILPAYGMAETTLAVSFSECNAGLVVDEVDADLLAALRRAVPATKGNTRRLA
TLGPLLQDLEARIIDEQGDVMPARGVGVIELRGESLTPGYLTMGGFIPAQDEHGWYDTGD
LGYLTEEGHVVVCGRVKDVIIMAGRNIYPTDIERAAGRVDGVRPGCAVAVRLDAGHSRES
FAVAVESNAFEDPAEVRRIEHQVAHEVVAEVDVRPRNVVVLGPGTIPKTPSGKLRRANSV
TLVT*

Genomic Sequence

>Rv1013
TTGAGCAGGTTCACCGAGAAGATGTTCCACAATGCCCGCACCGCGACGACGGGCATGGTC
ACAGGTGAACCGCACATGCCCGTCCGCCACACCTGGGGCGAGGTCCATGAGCGTGCTCGT
TGCATCGCGGGCGGCCTGGCCGCCGCGGGTGTCGGTCTTGGTGACGTTGTTGGGGTGCTG
GCCGGCTTCCCGGTGGAGATCGCCCCCACGGCGCAGGCCCTGTGGATGCGCGGGGCCAGC
CTGACCATGCTGCACCAGCCCACACCGCGCACCGACTTGGCCGTGTGGGCCGAGGACACC
ATGACCGTCATCGGCATGATCGAGGCCAAGGCCGTGATCGTCTCCGAGCCCTTCCTCGTG
GCCATTCCCATCCTTGAGCAGAAAGGCATGCAGGTCCTTACCGTCGCTGACCTTTTGGCG
TCGGATCCGATCGGCCCCATCGAGGTCGGCGAGGACGACCTGGCGTTGATGCAGCTGACG
TCCGGATCTACCGGCTCCCCTAAAGCCGTCCAGATCACCCACCGCAACATCTACTCCAAC
GCCGAGGCAATGTTCGTCGGCGCCCAGTATGACGTCGACAAGGACGTCATGGTCAGCTGG
TTGCCCTGCTTCCATGACATGGGCATGGTGGGCTTCTTGACTATCCCGATGTTCTTCGGT
GCGGAGCTGGTCAAGGTCACGCCAATGGACTTCCTGCGCGACACGCTGCTGTGGGCGAAG
CTCATCGACAAGTACCAGGGCACCATGACCGCGGCGCCCAACTTCGCCTACGCGCTGCTC
GCCAAGCGGTTGCGGCGCCAGGCCAAGCCCGGCGACTTCGATCTGTCGACCCTACGCTTC
GCGCTGTCCGGCGCCGAGCCCGTCGAACCCGCCGACGTCGAGGACCTGCTCGACGCGGGC
AAGCCGTTCGGCCTGAGGCCCTCAGCGATCCTGCCGGCCTACGGCATGGCCGAGACCACG
CTGGCGGTGTCCTTCTCGGAGTGCAACGCCGGCCTCGTCGTGGACGAGGTTGACGCCGAC
CTGCTGGCGGCTCTGCGCCGGGCCGTTCCCGCCACCAAAGGCAATACCCGCAGGCTGGCC
ACGCTAGGTCCGCTGCTGCAGGACCTAGAGGCCCGCATCATCGACGAACAGGGCGATGTC
ATGCCCGCCCGCGGCGTGGGTGTCATCGAGCTGCGCGGCGAGTCGCTAACTCCCGGCTAC
CTGACTATGGGTGGCTTCATCCCGGCCCAAGACGAGCATGGCTGGTACGACACGGGCGAC
CTCGGCTACCTCACCGAGGAGGGCCACGTGGTGGTATGTGGCCGCGTCAAGGATGTCATC
ATCATGGCCGGGCGCAATATTTACCCGACCGACATCGAGCGGGCGGCCGGCCGCGTCGAC
GGCGTTCGTCCGGGTTGCGCGGTGGCCGTGCGTCTCGATGCCGGACATTCGCGCGAATCC
TTTGCCGTCGCGGTCGAGTCGAACGCCTTCGAGGATCCCGCCGAGGTTCGTCGCATCGAG
CATCAAGTGGCCCACGAGGTGGTTGCCGAGGTCGACGTGCGGCCTCGCAACGTCGTGGTT
CTTGGACCCGGGACCATTCCGAAGACGCCGTCGGGCAAGCTGCGTCGGGCCAACTCCGTC
ACCCTGGTCACCTAA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv0981	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. H. He, R. Hovey et al. MprAB is a stress-responsive two-component system that directly regulates expression of sigma factors SigB and SigE in Mycobacterium tuberculosis. J. Bacteriol. 2006
Interaction	RegulatedBy Rv2711	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. GM. Rodriguez, MI. Voskuil et al. ideR, An essential gene in mycobacterium tuberculosis: role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress response. Infect. Immun. 2002