Rv1791 - PE family protein


Protein Domains

Gene Information
LocusRv1791
SymbolPE19
Gene NamePE family protein
Location2029904 - 2030203 (+)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:300 bp
Protein:100 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
Search Google Scholar
Orthologs
Orthogroup Number11498
Related GenesMAP1507 MAV_2923 MT1837 MT1840 MUL_3084 MUL_3088 Rv1788
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
Search for regulators of Rv1791
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionPhysicalInteraction Rv1793activegaat3s2012-10-05
Co-expression (Functional linkage)
KL. Lightbody, D. Ilghari et al. Molecular features governing the stability and specificity of functional complex formation by Mycobacterium tuberculosis CFP-10/ESAT-6 family proteins. J. Biol. Chem. 2008
InteractionPhysicalInteraction Rv1793activegaat3s2012-10-05
Co-expression (Functional linkage)
authors,B. Sidders,M. Withers,SL. Kendall,J. Bacon,SJ. Waddell,J. Hinds,P. Golby,F. Movahedzadeh,RA. Cox,R. Frita,AM. Ten Bokum,L. Wernisch,NG. Stoker Quantification of global transcription patterns in prokaryotes using spotted microarrays. Genome Biol. 2007
InteractionPhysicalInteraction Rv1792activegaat3s2012-10-05
Co-expression (Functional linkage)
authors,B. Sidders,M. Withers,SL. Kendall,J. Bacon,SJ. Waddell,J. Hinds,P. Golby,F. Movahedzadeh,RA. Cox,R. Frita,AM. Ten Bokum,L. Wernisch,NG. Stoker Quantification of global transcription patterns in prokaryotes using spotted microarrays. Genome Biol. 2007
InteractionPhysicalInteraction Rv1792activegaat3s2012-10-05
Co-expression (Functional linkage)
KL. Lightbody, D. Ilghari et al. Molecular features governing the stability and specificity of functional complex formation by Mycobacterium tuberculosis CFP-10/ESAT-6 family proteins. J. Biol. Chem. 2008
InteractionPhysicalInteraction Rv1793activegaat3s2012-10-05
Co-expression (Functional linkage)
authors,B. Sidders,M. Withers,SL. Kendall,J. Bacon,SJ. Waddell,J. Hinds,P. Golby,F. Movahedzadeh,RA. Cox,R. Frita,AM. Ten Bokum,L. Wernisch,NG. Stoker Quantification of global transcription patterns in prokaryotes using spotted microarrays. Genome Biol. 2007
InteractionPhysicalInteraction Rv1792activegaat3s2012-10-05
Co-expression (Functional linkage)
authors,B. Sidders,M. Withers,SL. Kendall,J. Bacon,SJ. Waddell,J. Hinds,P. Golby,F. Movahedzadeh,RA. Cox,R. Frita,AM. Ten Bokum,L. Wernisch,NG. Stoker Quantification of global transcription patterns in prokaryotes using spotted microarrays. Genome Biol. 2007
SymbolPPE25-PE19activejlew2012-03-07
Mutant is defective in ESXN and PPE41 secretion. Mutant is attenuated in macrophages and SCID mice.
authors,D. Bottai,M. Di Luca,L. Majlessi,W. Frigui,R. Simeone,F. Sayes,W. Bitter,MJ. Brennan,C. Leclerc,G. Batoni,M. Campa,R. Brosch,S. Esin Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation. Molecular microbiology 2012