Rv2950c - fatty-acid-CoA ligase fadD29
Protein Domains

Gene Information
LocusRv2950c
SymbolfadD29
Gene Namefatty-acid-CoA ligase fadD29
Location3300596 - 3302455 (-)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:1860 bp
Protein:620 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number31647
Related GenesCE2557 cg3003 DIP2009 jk0270 ML0132 ML0134 ML0135 MT3018 MT3021 MT3023 MUL_2002 MUL_2004 MUL_2005 nfa12430 Rv2946c Rv2947c Rv2948c
Transcriptional Regulation
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Regulatory Network
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Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionRegulatory Rv0348activeashwinigbhat2012-10-05
Co-expression (Functional linkage)
B. Abomoelak, EA. Hoye et al. mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2009
InteractionOperon Rv2948cactiveashwinigbhat2012-10-05
Co-expression (Functional linkage)
B. Abomoelak, EA. Hoye et al. mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2009
InteractionOperon Rv2949cactiveashwinigbhat2012-10-05
Co-expression (Functional linkage)
B. Abomoelak, EA. Hoye et al. mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2009
InteractionOperon Rv2949cactiveashwinigbhat2012-10-05
Co-expression (Functional linkage)
B. Abomoelak, EA. Hoye et al. mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2009
InteractionRegulatedBy Rv0348activeyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
B. Abomoelak, EA. Hoye et al. mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2009
InteractionRegulatedBy Rv1221activeyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
R. Manganelli, MI. Voskuil et al. The Mycobacterium tuberculosis ECF sigma factor sigmaE: role in global gene expression and survival in macrophages. Mol. Microbiol. 2001
NameFatty acyl-AMP ligase involved in the biosynthesis of phenolic glycolipids; catalyzes the activation of hydroxyphenylalkanoates which are then transferred onto PpsA to yield phenolphthiocerolactivemjackson2012-10-05
Phthiocerol dimycocerosates (PDIM), phenolic glycolipids (PGL) and para-hydroxybenzoic acid derivatives
NameFatty acyl-AMP ligase involved in the biosynthesis of phenolic glycolipids; catalyzes the activation of hydroxyphenylalkanoates which are then transferred onto PpsA to yield phenolphthiocerolactivemjackson2012-10-05
Phthiocerol dimycocerosates (PDIM), phenolic glycolipids (PGL) and para-hydroxybenzoic acid derivatives
OtherTBPWY:Phthiocerol dimycocerosates, PGL & pHBADactivemjackson2012-03-05
Fatty acyl-AMP ligase involved in the biosynthesis of phenolic glycolipids; catalyzes the activation of hydroxyphenylalkanoates which are then transferred onto PpsA to yield phenolphthiocerol (phenotypic [mycobacterial recombinant strains]; enzymatic)
authors,R. Siméone,M. Léger,P. Constant,W. Malaga,H. Marrakchi,M. Daffé,C. Guilhot,C. Chalut Delineation of the roles of FadD22, FadD26 and FadD29 in the biosynthesis of phthiocerol dimycocerosates and related compounds in Mycobacterium tuberculosis. FEBS J. 2010